Scienmag

SEPTEMBER 23, 2020

– Viral and bacterial pathogens wield pathogenic or virulent proteins that interact with high-value targets inside human cells, attacking what is known as the host interactome. The host interactome is the network map of all the protein-protein […]. Credit: UAB BIRMINGHAM, Ala.

Protein 85

Protein Drugs Bioinformatics Genetics 85

pharmaphorum

JULY 5, 2022

The new partnership will apply Mogrify’s cellular reprogramming and bioinformatics expertise to try to identify transcription factors – proteins which can turn specific genes on or off – that can be used to generate new cochlear hair cells. An estimated 1.57

In-Vivo 110

In-Vivo Bioinformatics Genetics Licensing 110

Scienmag

JULY 15, 2021

A subset of fibroblasts located in small foci of tissue on the edges of extensive scarring produce a protein that protects against cell aging. Credit: Nakahara Y, Hashimoto N, Sakamoto K, et al.

RNA 98

RNA Protein Bioinformatics Medicine 98

Scienmag

JANUARY 27, 2021

The thought of eating insects is stomach turning for many, but new Edith Cowan University (ECU) research is shedding light on allergy causing proteins which could pose serious health risks for those suffering from shellfish allergy Credit: Edith Cowan University The thought of eating insects is stomach turning for many, but new Edith Cowan University (..)

Allergies 98

Allergies Protein Research Bioinformatics 98

Scienmag

MAY 27, 2021

CAV1 is a protein associated with poor outcomes in aggressive breast and prostate cancer. Credit: SFU SFU computing science professor Ghassan Hamarneh is using his medical imaging analysis expertise to help UBC researchers understand the role of caveolin-1 (CAV1) in certain cancer types.

Research 92

Research Protein Bioinformatics Engineer 92

The Pharma Data

DECEMBER 16, 2020

Evotec and Bristol Myers Squibb (the successor in interest to Celgene ) initiated their long-term strategic drug discovery and development partnership in the field of targeted protein degradation in 2018 with the goal to identify novel drug targets.

Protein 40

Protein Bioinformatics Containment Drugs 40

pharmaphorum

APRIL 1, 2021

“For example, you can simulate what would happen if you inhibited thousands of different proteins in thousands of different cell models.”. They go into bioinformatics”. They go into bioinformatics.”. There are a lot of scientists who want to better understand biology but don’t have the money to do it in wet settings.

Bioinformatics 123

Bioinformatics Drugs Development Scientist 123

pharmaphorum

SEPTEMBER 16, 2022

A mere six months ago Verily launched the study with Sosei Heptares – a global leader in GPCR structure-based drug design – with an aim to “prioritise protein targets for therapeutic targeting in immune-mediated disease”. What, then, is the solution? About the interviewee.

Development 135

Development Research Drugs Clinical Trials 135

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. Bioinformatic techniques are then used to piece together the reads into a continuous genomic sequence by aligning them to the reference human genome.

Genomics 119

Genomics Genome Medicine Gene 119

Scienmag

OCTOBER 27, 2020

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential drug targets, in proteins. BiteNet can analyze 1,000 protein structures in 1.5 The research […].

Drugs 59

Drugs Protein Engineer Scientist 59

pharmaphorum

MARCH 28, 2022

AION Labs’ third call for applications seeks computational biologists, bioinformatics and cheminformatics scientists, AI researchers, and antibody or protein engineers at academic and industry research labs worldwide to assemble a fully funded start-up company.

Pharma Companies 98

Pharma Companies Antibody Protein Development 98

pharmaphorum

OCTOBER 20, 2021

In the new trial, Ionian University’s Bioinformatics and Human Electrophysiology Laboratory (BiHeLab) will deploy analytical methods to the data generated in the trial and monitor the molecular events underpinning the development of Alzheimer’s, including protein misfolding.

Trials 78

Trials Genomics Genome Bioinformatics 78

Scienmag

JULY 1, 2021

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

RNA 60

RNA Protein Research Gene 60

Scienmag

DECEMBER 22, 2020

Credit: Kanazawa University Nowadays nanotechnology allows to observe single proteins at work. Under atomic force microscopy (AFM), e.g., their surface can be rapidly scanned, and functional motions monitored, which is of great importance for applications in all fields of Life science.

Life Science 52

Life Science Protein Bioinformatics Engineer 52

Roots Analysis

AUGUST 28, 2022

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS), single-cell analysis, flow cytometry and mass spectrometry.

Genomics 52

Genomics Genome RNA Genome Project 52

Scienmag

MAY 27, 2021

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function.

Gene Expression 41

Gene Expression RNA DNA Protein 41

Scienmag

MARCH 4, 2021

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

Protein 46

Protein Medicine Drugs Research 46

Scienmag

AUGUST 11, 2020

Researchers from Skoltech, Lomonosov Moscow State University, and the Kharkevich Institute for Information Transmission Problems have studied the genomes of some 200 strains of bacteria to determine which proteins in the ribosome, part of the key cell machinery, can be safely lost and why.

Bacteria 41

Bacteria Genomics Genome Protein 41

XTalks

DECEMBER 13, 2023

This impressive growth can be attributed to Fulgent’s distinctive chemistries and advanced proprietary bioinformatics pipeline, which have been instrumental in fueling the company’s rapid advancement in recent years. Alpine Immune Sciences has recently announced an augmentation in its R&D investment. million and $38.8 million and $33.9

Genetics 111

Genetics Vaccination Vaccine DNA 111

STAT News

MARCH 6, 2023

“There isn’t a member of the board of JLF who wouldn’t rather be able to do this without charging people,” said Andrew Jacobs, who sits on the boards of the foundation and NorRD Bio, a small Cambridge bioinformatics firm that helps make the vaccines. “It really was a choice of this or nothing.”

Vaccination 98

Vaccination Vaccine Drugs Clinical Trials 98

XTalks

NOVEMBER 7, 2022

Optimal methods for bioinformatic analysis are still needed. Exosomes are extracellular vesicles that contain molecular cargoes (such as various proteins, RNAs and DNAs) specific to the origin cell. There is a high risk of false positives and false negatives (variant allele frequencies [VAFs] at frequencies <0.5

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

The Pharma Data

JULY 27, 2021

Teneobio’s discovery platform, TeneoSeek, comprises genetically engineered animals (UniRat® and OmniFlic®), next-generation sequencing, bioinformatics and high-throughput vector assembly technologies. TeneoSeek rapidly identifies large numbers of unique binding molecules specific for therapeutic targets of interest.

Production 52

Production Antibody Sales Development 52

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. Moving on From the Amyloid Hypothesis. “I A Whole New ‘Science Matters’ Perspective . “I

Vaccination 52

Vaccination Vaccine Regulation Drugs 52

The Pharma Data

SEPTEMBER 1, 2020

Inhibition of drug transporter breast cancer resistance protein has no effect on the pharmacokinetics of major active metabolites of ozanimod. Presentation Topic: Biomarkers and Bioinformatics. Presentation Number: P1133. Presentation Topic: Reproductive Aspects and Pregnancy. Studies Evaluating Zeposia Benefit to Risk Profile.

Trials 52

Trials Clinical Trials Clinical Trials Vaccine 52

Roots Analysis

JANUARY 27, 2025

Protein therapeutics have completely revolutionized the healthcare segment, greatly influencing the study and treatment of human diseases by conferring precise targeting ability to therapeutic modalities. Considering their vast potential, close to 50% of the top selling drugs in 2023 were protein therapeutics.

Protein 40

Protein Reagent Marketing Gene 40

XTalks

MARCH 11, 2025

These methods often require extensive sample preparation, complex bioinformatics or specialized lab environments, making them less ideal for quality control and release testing, where multiple mRNA constructs are already mixed.

Vaccination 64

Vaccination Vaccine Development Manufacturing 64