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NSF backs bioinformatics approach to understanding plant RNA modifications

Scienmag

Led by Boyce Thompson Institute’s Andrew Nelson, four partners will identify RNA modifications and develop resources that may lead to hardier crops Credit: Photo credit: Anna Nelson Dittrich ITHACA, NY, August 4, 2020 — RNA perform a variety of functions in cells, helping with everything from regulating genes to building proteins.

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PanOmics: Advancing drug discovery

Drug Discovery World

The technologies cover the whole range of biomolecules from genes to protein to metabolites. Using classical bulk (deep) RNA-Seq on thousands of human blood and tissue samples, Evotec has been building a high-quality molecular patient database – E.MPD. phosphorylations or ubiquitinations).

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Researchers hone in on the best software for detecting microRNAs in plants

Scienmag

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

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Key early steps in gene expression captured in real time by CSU researchers

Scienmag

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function.

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Sensyne, Oxford University deploy AI to find asthma targets

pharmaphorum

The partners will also examine the transcriptomes of around 60 participants – in other words the messenger RNA coded for by genes that in turn is used to produce proteins – and carry out bioinformatic analyses to tease out new pathways involved in asthma.

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Looking ahead to AACR  

Drug Discovery World

These topics will be represented across a range of session types, including methods workshops, minisymposia, poster and plenary sessions, as well as keynotes, awards and lectures.

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STAT+: Foundation charges cancer patients $83,000 for unproven but promising experimental drug

STAT News

Cambridge-based Moderna recently reported encouraging results from a study of another type of personalized cancer vaccine it developed with the pharmaceutical giant Merck; it uses messenger RNA technology to target advanced melanoma. Neoantigen vaccines are designed to target certain proteins called neoantigens on tumor cells.