pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. Bioinformatic techniques are then used to piece together the reads into a continuous genomic sequence by aligning them to the reference human genome.

Genome 119

Genome Genomics Medicine Gene 119

XTalks

SEPTEMBER 5, 2023

The EMA and other agencies have stringent regulations and guidelines that cover the design of clinical development programs for new vaccines intended to provide pre- and post-exposure prophylaxis against infectious diseases.

Vaccine 96

Vaccine Vaccination Development Clinical Trials 96

pharmaphorum

APRIL 15, 2021

Collaboration when innovating in areas of high unmet medical need is critical and at Astellas, it means experts with highly specialised knowledge of these new discoveries often work in close partnership with regulators. “We We connect these subject matter experts with the regulatory authorities to facilitate information exchange.

Development 76

Development Manufacturing Production Bioinformatics 76

Trialfacts

SEPTEMBER 12, 2024

Their work is driven by a profound understanding of disease biology and supported by advanced discovery platforms such as genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and various animal models.

Research 52

Research Gene Editing Biobanking Bioinformatics 52

STAT News

MARCH 6, 2023

“There isn’t a member of the board of JLF who wouldn’t rather be able to do this without charging people,” said Andrew Jacobs, who sits on the boards of the foundation and NorRD Bio, a small Cambridge bioinformatics firm that helps make the vaccines. “It really was a choice of this or nothing.”

Vaccine 98

Vaccine Vaccination Drugs Clinical Trials 98

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. 2020 Was Educational for Industry & Regulators.

Vaccination 52

Vaccination Vaccine Regulation Drugs 52

XTalks

NOVEMBER 7, 2022

Optimal methods for bioinformatic analysis are still needed. Regulators may ask at some point to provide that documentation, so it’s important to track that across the study. There is a high risk of false positives and false negatives (variant allele frequencies [VAFs] at frequencies <0.5 percent show less reliability).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

The Pharma Data

JULY 27, 2021

Teneobio’s discovery platform, TeneoSeek, comprises genetically engineered animals (UniRat® and OmniFlic®), next-generation sequencing, bioinformatics and high-throughput vector assembly technologies. About Teneobio Teneobio, Inc. Our business may be impacted by government investigations, litigation and product liability claims.

Production 52

Production Antibody Sales Development 52

XTalks

MARCH 11, 2025

These methods often require extensive sample preparation, complex bioinformatics or specialized lab environments, making them less ideal for quality control and release testing, where multiple mRNA constructs are already mixed.

Vaccine 64

Vaccine Vaccination Development Manufacturing 64