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The team has focused initially on non-small cell lung cancer (NSCLC), the most common form of lung cancer, but say the same principles could be applied to other tumour types, and combined with other testing approaches like genomics to inform treatment decisions.
Approximately 85% of rare diseases are genetic, offering significant opportunities to develop better treatments as our understanding of the human genome improves 1. Scientists have identified responsible genes for approximately 50% of the estimated 7000 rare diseases 2. How do you find rare disease patients?
Berlin, March 23, 2021 – Bayer announced today that the Japanese Ministry of Health, Labor and Welfare (MHLW) has granted marketing authorization for larotrectinib, under the brand name Vitrakvi , for the treatment of Neurotrophic Tyrosine Receptor Kinase ( NTRK ) fusion-positive advanced or recurrent solid tumors. Fields, M.D.,
Almost two decades after the human genome was sequenced, a trickle of new genetic medicines (i.e., those that modify the expression of an individual’s genes or repair abnormal genes) has entered clinical practice, including 11 RNA therapeutics, 2 in vivo gene therapies, and 2 gene-modified cell therapies.
Data from four distinct analyses for Vitrakvi (larotrectinib) showcase its sustained clinical benefit for patients with solid tumors harboring an NTRK gene fusion (also referred to as TRK fusion cancer). About TRK Fusion Cancer TRK fusion cancer occurs when an NTRK gene fuses with another unrelated gene, producing a chimeric TRK protein.
Israel and Taiwan under the brand name Aliqopa. While local labels might differ, the product is approved for adult and pediatric patients with solid tumors that harbor a NTRK gene fusion and have no satisfactory alternative treatments. Vitrakvi is approved in multiple countries around the world, including the U.S., EU, UK and Japan.
Another key focus at Bayer is on innovative precision oncology treatments, with an approved TRK inhibitor exclusively designed to treat tumors that have an NTRK gene fusion, the oncogenic driver of tumor growth and spread. The Bayer brand stands for trust, reliability and quality throughout the world. billion euros. billion euros.
By fostering a sense of community, addressing pain points and sharing impactful stories, podcasts can strengthen ties with an audience, drive brand loyalty and help life science organizations position themselves for long-term success in an increasingly competitive landscape.
Marieke Oudelaar (Max Planck Institute for Biophysical Chemistry in Göttingen) for her outstanding contributions in the development of methods to characterize the 3D structure of the genome and her work on the interaction between gene-regulatory elements at specific gene loci. Dr. Connor W. billion euros. billion euros.
(NYSE: TMO) today announced they have entered into a collaboration agreement to help increase local access to next-generation sequencing (NGS)-based testing for lung and breast cancer patients in more than 30 countries across Latin America, Africa, the Middle East and Asia where advanced genomic testing has previously been limited or unavailable.
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Affinia Therapeutics raises $110 million for gene therapy treatments ( STAT ).
New variant-hardy AbCellera-Lilly mAb shows utility of viral genomics surveillance ( BioCentury ).
Startup sets out to tackle the gene therapy manufacturing crisis ( Endpoints ).
Medtech.
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