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Such therapies may involve small interfering RNA (siRNA) or oligonucleotides in viral transfection platforms, large molecules and antibodies. Biogen’s nusinersen (brand name Spinraza) is an antisense oligonucleotide (ASO) therapy that is administered directly into the CNS by intrathecal injection through lumbar puncture.
The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. Meanwhile, don’t chalk one up for Sanofi, who makes the branded formulation (Plaquenil) of hydroxychloroquine (HCQ). Fujifilm Favipiravir (Avigan) Inhibits RNA-dependent RNA polymerase.
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