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Although only a small number of gene therapies have reached the market thus far, the industry is poised to grow quickly over the next few years. According to GlobalData’s clinical trials database, there are currently 1,231 planned and ongoing trials for gene therapies and gene-modified cell therapies alone.
The most common marketed drugs in this space aim to address the hyperammonaemia caused by the defective genes in this disorder. Ultragenyx uses adeno-associated virus 8 (AAV8) gene therapy to induce stable OTC gene expression. This treatment activates the OTC gene so that ammonia can be removed from the blood.
In an interview with BioSpace, Marianne De Backer, Head of BusinessDevelopment & Licensing in Bayer’s Pharmaceuticals Division, outlined Bayer’s thought process for opening its purse strings and diving into the deep end of the cell and gene therapy space.
Marianne De Backer, Head of BusinessDevelopment & Licensing in Bayer’s Pharmaceuticals Division, pictured above. Also in December, the company partnered with Atara Biotherapeutics to develop off-the-shelf T-cell immunotherapies for high mesothelin-expressing tumors. Photo courtesy of Bayer.
.–( BUSINESS WIRE )– EdiGene, Inc. which develops genome editing technologies to accelerate drug discovery and develop novel therapeutics for a broad range of diseases, today announced the appointment of Bo Zhang, Ph.D., as Head of BusinessDevelopment. Both will report to Dr. Dong Wei, CEO of EdiGene.
All eyes may be on Moderna’s COVID-19 vaccine at the moment, but the US biotech hasn’t been idle in businessdevelopment elsewhere, signing back-to-back deals with Vertex and Chiesi that have brought in $100 million upfront. .
Senior Vice President, BusinessDevelopment, will present at the annual 2020 Cell & Gene Virtual Meeting on the Mesa. BURLINGTON, Mass., 08, 2020 (GLOBE NEWSWIRE) — Flexion Therapeutics, Inc. Nasdaq:FLXN) announced today that Adam Muzikant, Ph.D., Dr. Muzikant will provide a … Continue reading →
Senior Vice President, BusinessDevelopment, will present at the annual 2020 Cell & Gene Virtual Meeting on the Mesa. BURLINGTON, Mass., 08, 2020 (GLOBE NEWSWIRE) — Flexion Therapeutics, Inc. Nasdaq:FLXN) announced today that Adam Muzikant, Ph.D., Dr. Muzikant will provide a … Continue reading →
Before the industry is set to arrive in San Diego for Bio International 2024, we spoke with Dr. Harald Oberegger, global head businessdevelopment at Novartis Contract Manufacturing.
Fortunately, we are now experiencing significant progress in gene therapy and other platform approaches targeting rare diseases, with a number of them focused on devastating CNS conditions. This is and should be a priority for our health system. We need to work together to solve it. About the author.
Bayer strengthens gene therapy portfolio with lipid nanoparticle technology from Acuitas Therapeutics Bayer AG is joining forces with Acuitas Therapeutics, Inc., a biotechnology company specializing in the development of lipid nanoparticle (LNP) delivery systems for molecular therapeutics. Financial details were not disclosed.
CRISPR Therapeutics and Vertex are also in the running with their gene-editing candidate CTX001, in phase 1/2 trials which are due to generate final results later this year. If those results are positive the partners have said they could file for approval in the US before year-end. It comes shortly after the group closed a $6.7
The increase in the production of biological drugs such as vaccines, gene and cell therapies, and monoclonal antibodies, is increasing the volume of injectable drug products in the global healthcare market.
Now, he leads Whitelab Genomics as its artificial intelligence (AI) platform powers the development of genomic therapies – an emerging field in which genetic sequences are injected into cells to target and repair damaged genes. and France to accelerate the development of genomic therapies. The evolving field of genomic medicine.
CureLab has appointed Jihad Fakhreddine as director of businessdevelopment, representing CureLab in the region. After 20+ years of successful businessdevelopment in the USA and Switzerland , he moved to Dubai to lead international healthcare and fundraising projects.
The committee is tasked with supporting BeyondSpring’s businessdevelopment activities related to its lead asset, Plinabulin, and other pipeline assets. Mukul Agarwal, former vice president of Corporate Development, at Forty Seven, Inc., Mukul Agarwal, former vice president of Corporate Development, at Forty Seven, Inc.,
Dan McDonald, vice president, global businessdevelopment. Imogen Cheese, Imperial director of businessdevelopment, U.K. Wearables will be developed that notify patients and EMS services of precursors to adverse events. Gene counselors and genetic testing. Instead we are blasting forward at record pace.
” ArsenalBio’s platform makes use of automation, large-scale genome engineering, using technologies like CRISPR-based gene-editing, and machine learning and artificial intelligence algorithms to design, build, and test cell therapies.
Sanofi Ventures invests in innovators working in areas including immunology and inflammation, rare diseases, oncology, cell and gene therapy, vaccines, and digital health and data science.
It has made Oxford Nanopore’s chief executive and cofounder Gordon Sanghera an on-paper fortune of £63 million, while another cofounder – chief businessdevelopment officer Spike Willcocks – is now worth £30 million. Chief technology officer Clive Brown is also sitting on a £10 million stake.
Maishman brings a wealth of experience to the cell and gene therapy-focused company, having worked at GlaxoSmithKline, Pfizer, Valneva, Alexion, and Recipharm in various leadership roles. Reagents supplier The Native Antigen Company has hired a new businessdevelopment manager, Richard White , and senior product manager, Pardeep Sharda.
The funding will offer capital to extend Blueprint’s varied pipeline toward marketing as well as to continue seeking strategic and synergistic businessdevelopment prospects. Be Bio Blueprint Medicines Endeavor BioMedicines Kallyope Metagenomi Mineralys Neuron23 Nutcracker RayzeBio Rivus Ventus Therapeutics. Innovation.
Barnett joined Array in 2000, two years after the company was founded, and played an invaluable role in successfully bringing Mektovi and Braftovi, two precision oncology medicines, to market while serving in a range of roles including research, businessdevelopment and technical operations. Liquidia Corporation – N.C. Source link.
SpringWorks Therapeutics — Badreddin Edris has been promoted from chief business officer to COO and Mary Smith, Mary Smith, currently senior vice president of Clinical Research and Development, has been promoted to chief development officer at SpringWorks. Rinri Therapeutics – Terri Gaskell was named CTO of U.K.-based
In addition, LogicBio has a collaboration with Takeda to research and develop LB-301, an investigational therapy leveraging GeneRide for the treatment of the rare pediatric disease Crigler-Najjar syndrome. LogicBio is also developing a Next Generation Capsid platform for use in gene editing and gene therapies.
Prior to joining Calliditas Therapeutics as CMO, he held roles at GlaxoSmithKline (GSK) and Takeda, focusing on clinical and businessdevelopment in rare diseases. I’ve had a great passion for drug development in rare diseases,” says Dr. Philipson, underscoring a commitment that would shape his career’s trajectory.
They are committed to capitalizing on growth opportunities primarily through the advancement of their own product pipeline and constantly improving their existing products, as well as through businessdevelopment activities. Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A.
Velders is presently chairman of HollandBIO, the association of Dutch biotech companies, and provides years of experience, specifically in the cell and gene therapy areas. Before joining Kite, he was chief scientific officer at Dutch AM-Pharma, Business Unit Manager at TNO Biosciences and chief executive officer at SomantiX.
Aimovig retains strong payer coverage and remains the segment leader within the preventive calcitonin gene-related peptide (CGRP) class. R&D expenses increased 11% primarily due to higher research and early pipeline spend and late-stage development program spend, including our recent businessdevelopment activities.
Cell and gene therapies are predicted to be the future of medical treatment by providing the body with the means to repair itself and recover from a range of serious conditions and severe diseases. While cell and gene therapies are currently much more expensive than traditional medical treatments, the ultimate savings could be significant.
Research – and money – going into even more advanced gene therapies is ramping up. Genomics is set to have a major impact on understanding, preventing, and treating a huge range of diseases; cell and gene therapies will bolster oncology investment, for example, with several such drugs currently in development.
The purchase of Viroclinics-DDL, an established global specialist virology and vaccine development contract research organisation, gives Cerba Research the opportunity to enhance solutions across therapeutic areas, explore new geographies and build best-in-class logistics services, while reducing risks for customers.
They are called: “ Accelerating time to market through digitalisation ”, “ Why digital biomarkers will power tomorrow’s Alzheimer’s therapies ”, and “ The path to improved safety of gene-based products ”. The post The far-reaching impact of drug discovery technology appeared first on Drug Discovery World (DDW).
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