Bayer and Evotec link to develop precision cardiology therapeutics
Pharmaceutical Technology
MAY 1, 2024
Bayer and Evotec have expanded collaboration to focus on the development of precision treatments for cardiovascular diseases (CVDs).
NBA Legend Pau Gasol Invests in AI Cardiology Company Idoven
XTalks
SEPTEMBER 7, 2023
Los Angeles Lakers and Spain’s basketball legend Pau Gasol is investing in artificial intelligence (AI) company Idoven , which is developing an AI-powered cardiology service platform. Gasol joins Iker Casillas, Spain’s winning World Cup goalkeeper, as the second athlete to invest in the AI cardiology company.
Cardiology 
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UK regulator backs Amarin’s cardiology drug Vazkepa
pharmaphorum
APRIL 23, 2021
Amarin’s Vazkepa cardiology drug has been backed by the UK’s drugs regulator, following approval in Europe at the end of March. . The post UK regulator backs Amarin’s cardiology drug Vazkepa appeared first on. Icosapent ethyl also demonstrated a 26% relative risk reduction and a 3.6%
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Cardiology collaboration advances machine learning predictions for AFib after stroke
Medical Xpress
NOVEMBER 22, 2024
A team of artificial intelligence engineers, in collaboration with a team of physicians from Penn State Heart and Vascular Institute, is working to develop novel algorithms for point-of-care, in-house use and for technology licensing.
Cardiology 106
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Pfizer buys immuno-inflammatory firm Arena Pharmaceuticals for $6.7b
Outsourcing Pharma
DECEMBER 13, 2021
The pharmaceutical company currently has several promising treatments in development for gastroenterological, dermatological, and cardiological conditions.
Cardiology 145
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AGEPHA Pharma’s LODOCO gets US FDA approval for cardiovascular disease
Pharmaceutical Technology
JUNE 21, 2023
Participants treated with LODOCO had a 31% reduction in the overall risk of cardiovascular death, spontaneous myocardial infarction or ischaemic stroke when added to statins and other cardiology prevention therapies, compared to those treated with placebo.
FDA Approval 246
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Preeclampsia in mothers linked with four-fold higher risk of heart attack in decade after childbirth
Medical Xpress
JANUARY 25, 2023
Women with preeclampsia develop a higher likelihood of heart attack and stroke than their peers within just seven years of delivery, with risks remaining elevated more than 20 years later. The study of more than one million pregnant women is published today in the European Journal of Preventive Cardiology.
Cardiology 98
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Frequent marijuana use linked to heart disease
Medical Xpress
FEBRUARY 24, 2023
People who used marijuana daily were found to be about one-third more likely to develop coronary artery disease (CAD) compared with people who have never used the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.
Cardiology 75
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Developing a digital marker for coronary artery disease
Medical Xpress
DECEMBER 20, 2022
Using machine learning and clinical data from electronic health records, researchers at the Icahn School of Medicine at Mount Sinai in New York constructed an in silico, or computer-derived, marker for coronary artery disease (CAD) to better measure clinically important characterizations of the disease.
Development 145
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Study: Vitamin D, fish oil don’t lower atrial fibrillation risk
Scienmag
NOVEMBER 13, 2020
Smidt Heart Institute Chair of Cardiology presents new findings at American Heart Association Scientific Sessions Credit: Photo by Cedars-Sinai LOS ANGELES (Nov.
Cardiology 85
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Severe COVID-19 linked with 16-fold risk of life-threatening heart rhythm within 6 months
Medical Xpress
APRIL 18, 2023
Patients with severe COVID-19 requiring mechanical ventilation are 16 times more likely to develop ventricular tachycardia within six months compared to their peers without severe infection, according to research presented at EHRA 2023, a scientific congress of the European Society of Cardiology (ESC).
Cardiology 89
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Technology-assisted pregnancies have twice the risk of preeclampsia
Medical Xpress
FEBRUARY 24, 2023
People who became pregnant using assisted reproductive technologies were found to be over twice as likely to develop preeclampsia than those with traditional pregnancies, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.
Cardiology 74
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LUCA Science Announces Joint Research With Division of Cardiology, Field of Internal Medicine, Nagoya University Graduate School of Medicine on the Development of Mitochondrial Therapy for Myocardial Infarction (Cardiac Ischemic-reperfusion Injury)
BioTech 365
DECEMBER 1, 2020
LUCA Science Announces Joint Research With Division of Cardiology, Field of Internal Medicine, Nagoya University Graduate School of Medicine on the Development of Mitochondrial Therapy for Myocardial Infarction (Cardiac Ischemic-reperfusion Injury) LUCA Science Announces Joint Research With Division of Cardiology, … Continue reading →
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STAT+: Heart repair, risky genes, and AI: the buzz from a giant cardiovascular conference
STAT News
MARCH 6, 2023
NEW ORLEANS — Aptly or paradoxically, thousands of the world’s leading cardiologists descended on the home of beignets, bouillabaisse, and beers sold to-go for a weekend-long dive into the latest developments in the science of keeping hearts beating healthily.
Cardiology 98
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Researchers develop a web application to analyze hypertension statistics
Medical Xpress
APRIL 27, 2023
A research team from Wake Forest University School of Medicine has developed an open-source, web-based application that allows users to generate customized hypertension statistics using National Health and Nutrition Examination Survey (NHANES) data.
Development 93
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Grand Rounds December 15, 2023: Diversifying Clinical Trials: A Path Forward (Roxana Mehran, MD, FACC, FAHA, MSCAI, FESC)
Rethinking Clinical Trials
DECEMBER 20, 2023
Further efforts are urgently needed to increase diversity in the cardiology workforce, which will improve clinical trial diversity and cardiovascular health for all. Approaches from the whole scientific community to tackle the inequality in workforce, trial leadership and trial participants have to be developed.
Clinical Trials 140
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Alcohol may be more risky to the heart than previously thought
Scienmag
MAY 22, 2022
Madrid, Spain – 22 May 2022: Levels of alcohol consumption currently considered safe by some countries are linked with development of heart failure, according to research presented at Heart Failure 2022, a scientific congress of the European Society of Cardiology (ESC).1
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Regulator and Funder? FDA’s Orphan Products Grants Program awards significant funding to help move promising treatments through clinical development
FDA Law Blog
NOVEMBER 10, 2024
Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.
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Aircraft noise exposure increases damage from myocardial infarction, finds study
Medical Xpress
FEBRUARY 15, 2023
Traffic noise may play an essential role in the development and deterioration of ischemic heart disease.
HFpEF vs. HFrEF: How To Improve Heart Failure Drug Development
XTalks
APRIL 15, 2021
Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. The reverse could also be true whereby the development of coronary artery disease may impact heart rate. HFrEF vs. HFpEF.
Development 98
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Team studies immune response, proteins in blood of young adults who develop rare complication after COVID vaccination
Medical Xpress
JANUARY 4, 2023
In a new study by researchers from Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, a team extensively investigated the immune response of 16 adolescents and young adults who developed myocarditis after receipt of the COVID mRNA vaccine.
Autism tied to higher risk for developing cardiometabolic disease
Medical Xpress
FEBRUARY 1, 2023
Autism spectrum disorders may be associated with a higher risk for developing cardiometabolic diseases, according to a review published online Jan. 30 in JAMA Pediatrics.
Development 73
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Researchers develop a training app for post-stroke care
Medical Xpress
FEBRUARY 8, 2023
Rytis Maskeliūnas, a researcher at KTU's Faculty of Informatics, Lithuania together with an international team, has developed an app that will teach how to take care of a person who has suffered a stroke in a virtual environment. It is a condition that usually leaves the patient disabled, often requiring constant care.
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Newly developed AI uses combination of ECG and X-ray results to diagnose arrhythmic disorders
Scienmag
APRIL 22, 2021
of the Division of Cardiovascular Medicine, Department of Internal Medicine) have developed an AI that uses multiple kinds of test data to predict the location of surplus pathways in the heart called ‘accessory pathways’, which cause the heart […].
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Boehringer-backed digital health academy set for launch in UK
pharmaphorum
DECEMBER 3, 2021
The Digital Health Academy – developed with pharma company Boehringer Ingelheim – is part of a drive to get digital health tools and apps used more routinely in the management of health conditions, according to ORCHA. More than third (37%) of those polled were also HCPs themselves.
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Developing a smartwatch to detect unwitnessed out-of-hospital cardiac arrests
Medical Xpress
NOVEMBER 25, 2022
The University of Twente and its partners are developing a smart wearable to automatically and reliably detect out-of-hospital cardiac arrest (OHCA), and to trigger an immediate emergency response.
Development 75
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AI-powered stethoscope from Eko spots heart failure in seconds
pharmaphorum
FEBRUARY 1, 2022
A study has shown that a ‘smart’ stethoscope developed by US digital health company Eko can be used to screen people for heart failure in a few second during a standard physical examination. The device tested in the independent study combines a stethoscope used to listen to heart sounds with a single-lead electrocardiogram (ECG).
Cardiology 140
140 
Women more likely to die after heart emergency than men
Scienmag
MARCH 19, 2022
Sophia Antipolis – 19 March 2022: Women are less likely to receive lifesaving treatment for cardiogenic shock than men, according to research presented today at ESC Acute CardioVascular Care 2022, a scientific congress of the European Society of Cardiology (ESC).1
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STAT+: Pharmalittle: Pfizer scaling back early-stage research into rare diseases; BioNTech and U.K. partner on cancer trials
STAT News
JANUARY 6, 2023
… Pfizer told employees it plans to pull back on early-stage research into treatments for rare diseases, including the development of new viral-based gene therapies , Barron’s reports. Among the assets on the chopping block is a gene therapy manufacturing facility in Durham, N.C.,
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Pregnancy-related hypertension can increase short-term risk
Scienmag
JUNE 13, 2022
fold increased risk of developing hypertension 10 years post pregnancy compared to women who did not experience any hypertensive disorders of pregnancy (HDP), according to a study published today in the Journal of the American College of Cardiology. Women who experience gestational hypertension or preeclampsia have a 2.4-fold
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Is cardiovascular disease a ‘pandemic hiding in plain sight’?
pharmaphorum
JUNE 25, 2021
But Dr Craig Granowitz, chief scientific officer of cardiology drug developer Amarin, says that this is only the tip of the iceberg when it comes to the devastating impact of CVD on global populations. “In Granowitz says that the most sobering statistic from the REDUCE-IT study actually comes from the control group. Think about that.
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Big babies could be at higher risk of common heart rhythm disorder in adulthood
Scienmag
OCTOBER 18, 2020
Beijing, China 19 Oct 2020: Elevated birth weight is linked with developing atrial fibrillation later in life, according to research presented at the 31st Great Wall International Congress of Cardiology (GW-ICC). Faculty from the European Society of Cardiology (ESC) will participate in joint scientific […].
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AstraZeneca to Acquire Alexion, Accelerating the Company’s Strategic and Financial Development
The Pharma Data
DECEMBER 12, 2020
Chief Executive Officer, Alexion , said: “For nearly 30 years Alexion has worked to develop and deliver transformative medicines to patients around the world with rare and devastating diseases. More recently, AstraZeneca has increased its efforts in immunology research and the development of medicines for immune-mediated diseases.
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Grand Rounds February 9, 2024: Pragmatic Recruitment of Underrepresented Groups – Experience From the Diuretic Comparison Project (Cynthia Hau, MPH)
Rethinking Clinical Trials
FEBRUARY 14, 2024
DCP developed an EHR-based workflows and integrated workflows within the local VA primary care setting. DCP developed 3 electronic workflows with 6 major configurations including applications needed outside of the EHR system. DCP developed a patient tracking tool that nurses could use to make sure patients got through each step.
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Researchers develop myocardial infarction treatment patch
Medical Xpress
DECEMBER 16, 2022
Myocardial infarction is an ischemic disease in which a coronary artery supplying blood to the heart muscle is stenotic or obstructed, resulting in cardiac tissue necrosis. Due to the irreversible loss of cardiomyocytes, damaged heart tissue cannot be naturally regenerated.
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Grand Rounds July 14, 2023: Lessons From the COORDINATE-Diabetes Trial (Christopher B. Granger, MD; Neha J. Pagidipati, MD, MPH)
Rethinking Clinical Trials
JULY 19, 2023
This was a cluster-randomized trial of 42 cardiology clinics across the U.S., The cardiology clinics were randomized to one of two groups. It is essential to scale this intervention across cardiology practices in order to improve the quality of care being delivered more broadly to ensure the implementation of these trial results.
Trials 100
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UMD Develops a DASH-Plus community-based hypertension management program for older adults
Scienmag
JULY 22, 2021
New USDA-NIFA funding brings together research, academics, and Extension to improve knowledge, access, and self-monitoring skills for hypertension management Credit: Edwin Remsberg, University of Maryland To address the significant health burden of hypertension (characterized by consistently high blood pressure), the University of Maryland (UMD) was (..)
Development 93
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Velocity Hosts Global CARE Council Summit
Velocity Clinical Research
MARCH 19, 2024
The summit focused on Velocity’s Diabetes + Obesity, MASH, Vaccine, Cardiology, and Women’s Health CARE Councils, along with a few areas in development.
Cardiology 52
52 Grand Rounds April 7, 2023: A Nudge Towards Cardiovascular Health: Incorporating Insights From Behavioral Science to Improve Cardiovascular Care Delivery (Srinath Adusumalli, MD, MSHP, MBMI, FACC)
Rethinking Clinical Trials
APRIL 13, 2023
The context and stakeholder input have been key in developing and implementing nudges. Discussion Themes – In the last few years, there has been great reception to the value of behavioral science and implementation science in the field of cardiology.
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Predicting development of postoperative acute kidney injury after coronary artery bypass grafting
Medical Xpress
FEBRUARY 16, 2023
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication that increases morbidity and mortality after cardiac surgery. Most established predictive models are limited to the analysis of nonlinear relationships and do not adequately consider intraoperative variables and early postoperative variables.
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Neurimmune announces ‘promising’ results for cardiomyopathy treatment
BioPharma Reporter
MAY 23, 2023
Neurimmune has announced that primary results of its phase 1 proof-of-concept study of NI006, a recombinant human antibody to deplete amyloid deposits in ATTR cardiomyopathy, have been presented in Prague at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC), and published in The New England Journal of Medicine.
Cardiology 52
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Heart failure is associated with an increased risk of cancer
Scienmag
JUNE 27, 2021
Sophia Antipolis – 28 June 2021: A study in more than 200,000 individuals has found that patients with heart failure are more likely to develop cancer compared to their peers without heart failure.
Cardiology 40
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Most Athletes With Heart Problems After COVID Can Return to Play
The Pharma Data
OCTOBER 31, 2020
With that in mind, the American College of Cardiology came up with some safety recommendations in May, which have now been revised. How many athletes with COVID-19 develop heart problems isn’t known, but the group said those who have moderate to severe coronavirus symptoms should be screened. 26 in JAMA Cardiology.
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How Phosphorus’ GeneCompass Preventative Genetic Test Can Help People Manage Their Health
XTalks
JULY 19, 2021
Phosphorus, a leading preventative genomics company, has developed the first comprehensive preventative genetic test for consumers. Phosphorus may be a familiar name as it was one of the first to develop an FDA-authorized at-home test for COVID-19 ; it was also the first test to have received an asymptomatic, direct-to-consumer FDA approval.
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