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Amarin’s Vazkepa cardiology drug has been backed by the UK’s drugs regulator, following approval in Europe at the end of March. . The Medicines and Healthcare products Regulatory Agency (MHRA) granted a marketing authorisation for Vazkepa (icosapent ethyl) as a treatment to reduce risk of cardiovascular events in high-risk patients.
Tom Zhang, PhD, Chief Scientific Officer, Large Molecule Bioanalysis Revolutionizing Therapeutic Development with Cutting-Edge Bioanalysis Automation Cutting-edge advancements in bioanalysis (BioA) and drug R&D are reshaping the future of preventative and interventional care, but how do we harness these to their fullest potential?
It can be used as a monotherapy or along with cholesterol-lowering medicines. Participants treated with LODOCO had a 31% reduction in the overall risk of cardiovascular death, spontaneous myocardial infarction or ischaemic stroke when added to statins and other cardiology prevention therapies, compared to those treated with placebo.
Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.
Using machine learning and clinical data from electronic health records, researchers at the Icahn School of Medicine at Mount Sinai in New York constructed an in silico, or computer-derived, marker for coronary artery disease (CAD) to better measure clinically important characterizations of the disease.
LUCA Science Announces Joint Research With Division of Cardiology, Field of Internal Medicine, Nagoya University Graduate School of Medicine on the Development of Mitochondrial Therapy for Myocardial Infarction (Cardiac Ischemic-reperfusion Injury) LUCA Science Announces Joint Research With Division of Cardiology, … Continue reading →
A Marketing Authorization Application has been submitted to the European Medicines Agency (EMA), with a decision anticipated in 2025. BridgeBio is also working to address gaps in ATTR-CM diagnosis through its TRACE-AI Network Study , a collaboration with the Cardiovascular Data Science Lab (CarDS Lab) at the Yale School of Medicine.
A research team from Wake Forest University School of Medicine has developed an open-source, web-based application that allows users to generate customized hypertension statistics using National Health and Nutrition Examination Survey (NHANES) data.
Diversity in clinical trials is important for generalizability of results, to provide equal opportunities, practice precision medicine, tailor practical guidelines, improve public health outcomes, detect potential differences in safety and efficacy, and to address health disparities. We have to change how we are practicing.
“Without clinical research, there would be little if any development of new medicines,” says Isabelle Schenkenberger, MD. An Internal Medicine Specialist since 2000, Dr. Schenkenberger has practiced at her own clinic since 2002. The post PI Savors Opportunity to Advance Medicine appeared first on Velocity Clinical Research.
of the Division of Cardiovascular Medicine, Department of Internal Medicine) have developed an AI that uses multiple kinds of test data to predict the location of surplus pathways in the heart called ‘accessory pathways’, which cause the heart […].
Smidt Heart Institute Chair of Cardiology presents new findings at American Heart Association Scientific Sessions Credit: Photo by Cedars-Sinai LOS ANGELES (Nov.
Credit: Mark Bauer/FSU College of Medicine Nearly a half-million people a year die from sudden cardiac death (SCD) in the U.S. — the result of malfunctions in the heart’s electrical system.
Nudges and other behavioral interventions are prevalent in industries like business and entertainment, but there is an opportunity for nudges in medicine and health care delivery. Launched in 2016, the Penn Medicine Nudge Unit is the world’s first behavioral design team embedded within a health system.
Mann Department of Biomedical Engineering have developed a "heart attack on a chip," a device that could one day serve as a testbed to develop new heart drugs and even personalized medicines. Researchers at the University of Southern California Alfred E.
Distinguished Professor of Medicine Professor of Nursing Duke University Neha J. This was a cluster-randomized trial of 42 cardiology clinics across the U.S., The cardiology clinics were randomized to one of two groups. Speaker Christopher B. Granger, MD Donald F. Fortin, M.D.
We look forward to welcoming our new colleagues at Alexion so that we can together build on our combined expertise in immunology and precision medicines to drive innovation that delivers life-changing medicines for more patients.” ” Ludwig Hantson , Ph.D., Strategic rationale.
An algorithm developed using artificial intelligence could soon be used by doctors to diagnose heart attacks with better speed and accuracy than ever before, according to new research from the University of Edinburgh published in Nature Medicine.
Department of Molecular Pharmacology, Shinshu University School of Medicine, Japan Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment. Credit: Mitsuhiko Yamada MD, PhD.,
Credit: Dr Maik Pietzner at the MRC Epidemiology Unit A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, cancer, chronic respiratory disease and diabetes.
Baynes, head of Global Clinical Development (GCD) and Chief Medical Officer, Merck Research Laboratories (MRL), will be retiring from Merck in July. Under his leadership, Merck has become a leading oncology company and achieved more than 140 medicine and vaccine approvals globally across numerous therapeutic areas.
Neurimmune has announced that primary results of its phase 1 proof-of-concept study of NI006, a recombinant human antibody to deplete amyloid deposits in ATTR cardiomyopathy, have been presented in Prague at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC), and published in The New England Journal of Medicine.
Using sophisticated modeling techniques, University of Maryland School of Medicine (UMSOM) researchers have developed a new tool that can predict the risk of heart disease in those over 40 based on their total exposure, through the years, to heart disease risk factors.
Beijing, China 19 Oct 2020: Elevated birth weight is linked with developing atrial fibrillation later in life, according to research presented at the 31st Great Wall International Congress of Cardiology (GW-ICC). Faculty from the European Society of Cardiology (ESC) will participate in joint scientific […].
New USDA-NIFA funding brings together research, academics, and Extension to improve knowledge, access, and self-monitoring skills for hypertension management Credit: Edwin Remsberg, University of Maryland To address the significant health burden of hypertension (characterized by consistently high blood pressure), the University of Maryland (UMD) was (..)
A KAIST research team led by Professor Keon Jae Lee from the Department of Materials Science and Engineering and the College of Medicine of the Catholic University of Korea has developed a highly sensitive, wearable piezoelectric blood pressure sensor.
With that in mind, the American College of Cardiology came up with some safety recommendations in May, which have now been revised. How many athletes with COVID-19 develop heart problems isn’t known, but the group said those who have moderate to severe coronavirus symptoms should be screened. 26 in JAMA Cardiology.
Identifies people at high risk of heart attack despite average LDL cholesterol levels Rome, Italy, March 8, 2021 – Allelica, a leading genomics software company specialising in developing polygenic risk scores (PRS) for personalised medicine, today announced publication of a study in Circulation (Vol.
The data could help doctors diagnose and treat athletes recovering from COVID-19 who have developed myocarditis, an inflammation of the heart. Chung is an electrophysiologist and sports cardiologist at Michigan Medicine and member of the Big Ten Cardiac Registry Steering Committee. She is on the steering committee for the registry.
A scientific review has found evidence that a disruption in blood clotting and the first line immune system could be contributing factors in the development of psychosis.
However, it wasn’t until 1959 – 73 years and two major acquisitions later – that J&J developed its significant presence in the pharmaceutical industry. These two acquisitions enabled the company to gain a significant presence in the field of pharmaceutical medicines for the first time. Where it all began.
Researchers at Penn Medicine uncover more genetic mutations that predispose women to peripartum cardiomyopathy, with implications for the future of increased genetic testing PHILADELPHIA– Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), (..)
Phosphorus, a leading preventative genomics company, has developed the first comprehensive preventative genetic test for consumers. Phosphorus may be a familiar name as it was one of the first to develop an FDA-authorized at-home test for COVID-19 ; it was also the first test to have received an asymptomatic, direct-to-consumer FDA approval.
Sophia Antipolis – 28 June 2021: A study in more than 200,000 individuals has found that patients with heart failure are more likely to develop cancer compared to their peers without heart failure.
Tools for clinicians in point-of-care use UTICA, NY — More than 2 million coronary artery stents are implanted each year to help protect or restore normal blood flow to the heart, to treat patients suffering from angina or a heart attack due to coronary artery disease (CAD). While stents are highly effective and safe devices, […].
Novo Nordisk is paying $55 million upfront to secure rights to a cell therapy for heart failure developed by Japanese startup Heartseed. Working out which are more likely to benefit from stem cell therapy is likely to be a key challenge for developers. An interim look at the results is due later this month.
The approval is based on the results of the pivotal Phase III VICTORIA trial, published in The New England Journal of Medicine (NEJM) in March 2020. Vericiguat is being jointly developed with MSD (a tradename of Merck & Co., The vericiguat program is being co-developed by Bayer and MSD. Verquvo (vericiguat) 2.5
Empagliflozin, a recently developed diabetes drug, can effectively treat and reverse heart failure in both diabetic and non-diabetic patients, according to researchers at the Icahn School of Medicine at Mount Sinai.
Heerspink, Professor of Clinical Trials and Personalized Medicine and a clinical pharmacologist/trialist at the Department of Clinical Pharmacy and Pharmacology at the University center Groningen, Netherlands, and Co-Chair of the study’s Executive Committee. The Bayer brand stands for trust, reliability and quality throughout the world.
An efficient intervention assessed by UACR reduction may provide long-term benefits for patients,” said Rajiv Agarwal, MD, Professor of Medicine, Indiana University School of Medicine and VA Medical Centre, Indianapolis, USA and Chair of the study’s Steering Committee. “If
He has used innovative and collaborative strategies to develop and refine a multi-modality ‘recruitment engine’ and led one of the UK’s first ‘virtual’ interventional trials. His main interest is in improving access to clinical trials through community-based participation, consent for contact registries and a digital media platform.
Boston, MA (May 1, 2021) – A new study presented today at the AATS 101st Annual Meeting, found that the percentage of patients undergoing esophagectomy for cancer who suffer Venous Thromboembolism (VTE) post-operatively is much higher than previously reported, with as many as 24 percent suffering from Deep Vein Thrombosis (DVT) or Pulmonary Embolism (..)
.–(BUSINESS WIRE)– Bristol Myers Squibb (NYSE: BMY) today announced that data from its cardiovascular portfolio will be presented at the American College of Cardiology’s 71st Annual Scientific Session (ACC.22), senior vice president, head of cardiovascular development and global drug development at Bristol Myers Squibb. “We
This blog provides a comprehensive look at the medical device giants, ranked by market capitalization , leading the charge into the future of medicine. Billion Boston Scientific continues to shape the future of medical technology with innovations across cardiology, neuromodulation and interventional procedures.
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