Scienmag

JUNE 16, 2022

Sophia Antipolis, 17 June 2022: Recommendations on how to use gene testing to prevent sudden cardiac death in athletes and enable safe exercise are published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).1

Cardiology 58

Cardiology Genetics Gene 58

Scienmag

JANUARY 28, 2021

— In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. ROCHESTER, Minn.

Gene Therapy 74

Gene Therapy Gene In-Vitro Clinical Research 74

Scienmag

SEPTEMBER 28, 2020

28, 2020 — A veteran’s study identified more than a dozen genes associated with abdominal aortic aneurysm (AAA) that could be used to better identify people at risk for the often-deadly condition, according to new research published today in the American Heart Association’s flagship journal Circulation.

Gene 74

Gene Research Cardiology Medicine 74

Medical Xpress

NOVEMBER 7, 2022

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association's Scientific Sessions (..)

Gene Editing 67

Gene Editing Gene Protein Research 67

Scienmag

MAY 5, 2021

Study published in JAMA Cardiology Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

Cardiology 53

Cardiology Genetics Gene Research 53

Scienmag

FEBRUARY 24, 2021

According to a new study published in The American Journal of Human Genetics, more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. These variants have an impact on the expression of genes regulating cholesterol metabolism, among other things. […].

Gene 52

Gene Genetics Regulation Cardiology 52

STAT News

JULY 12, 2022

Somewhere in New Zealand, the first patient ever has been dosed with a kind of gene-editing treatment known as a base editor, a newer way of utilizing CRISPR for gene editing. The company studying the treatment, Verve Therapeutics, announced the news Tuesday. Continue to STAT+ to read the full story…

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Gene Editing Gene Therapy Gene Cardiology 98

Scienmag

NOVEMBER 9, 2020

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

Gene 52

Gene Gene Expression Research Cardiology 52

XTalks

JULY 19, 2021

The test’s NGS technology achieves a clinical specificity of over 99 percent per condition and the test can detect over 99 percent of potential variants in each gene. As a preventative tool, the test can assist people in taking early action to help mitigate and even prevent health problems.

Genetics 98

Genetics Genome Genomics Gene 98

Medical Xpress

JANUARY 26, 2023

Research in a mouse model of diet-induced obesity has found greater disruption to genes involved in heart function when coupled with vitamin A deficiency using a combined dietary and genetic approach. The study is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology.

Genetics 107

Genetics Gene Research Cardiology 107

Medical Xpress

FEBRUARY 6, 2023

A genetic score may be able to identify higher stroke risk—but only for people living in the most privileged neighborhoods, according to new research that highlights inequities related to wealth and health.

Gene 75

Gene Genetics Research Cardiology 75

Scienmag

AUGUST 20, 2020

In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can […]. (..)

Genetics 41

Genetics Gene Genomics Genome 41

Medical Xpress

MAY 10, 2023

In an effort to determine the cause behind a rare condition that causes heart failure in children, University of Maryland School of Medicine (UMSOM) researchers have identified new gene mutations responsible for the disorder in an infant patient.

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Research Gene Medicine Drugs 98

Scienmag

DECEMBER 3, 2020

Those two key problems – safety and efficacy – are what continue to hold CRISPR-Cas9 gene targeting back from its full clinical potential, explains co-senior author Y. Eugene Chen, M.D., […].

Gene Editing 41

Gene Editing Gene DNA Genetics 41

Medical Xpress

JANUARY 20, 2023

A team of researchers at the University of Texas Southwestern Medical Center has found that it is possible in mice to protect the heart from ischemia-reperfusion using the CRISPR-Cas9 gene editing system.

Gene Editing 80

Gene Editing Genomics Genome Gene 80

Scienmag

APRIL 28, 2021

— A national, University at Buffalo-led study on genes in pediatric cardiomyopathy demonstrates strong evidence for routine genetic screening in children with the disease. The study, published April 28 in […].

Genetics 93

Genetics Gene Clinical Trials Clinical Trials 93

XTalks

APRIL 15, 2021

Dr. Benoit Tyl, MD, FESC, medical and scientific director, cardiology at Servier, says that the disconnect between correlation and causality in cardiovascular disease trials is partially responsible for the lack of approved HFpEF therapies. However, these drugs have shown limited effectiveness in treating HFpEF.

Development 98

Development Drugs Genome Genomics 98

Scienmag

JANUARY 26, 2021

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

Regulation 40

Regulation Gene Research Cardiology 40

Scienmag

MARCH 25, 2021

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (..)

Genetics 75

Genetics Gene Scientist Research 75

Scienmag

SEPTEMBER 24, 2020

New light is being shed on a little-known role of Y chromosome genes, specific to males, that could explain why men suffer differently than women from various diseases, including Covid-19.

Gene 60

Gene Research Cardiology Genetics 60

XTalks

SEPTEMBER 4, 2024

The data, presented at the European Society of Cardiology Congress 2024, suggest that vutrisiran could significantly reduce the risk of death and heart-related issues, marking a potential treatment breakthrough. Vutrisiran works by silencing the gene responsible for producing TTR, reducing both mutant and wild-type TTR proteins.

Trials 52

Trials RNA Protein Gene Editing 52

Scienmag

MARCH 31, 2021

Independent of cholesterol, gene variants raise risk of heart disease, diabetes, high blood pressure Credit: In-Hyuk Jung, PhD, Stitziel Lab High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

Scientist 62

Scientist Genetics Gene Medicine 62

Eye on FDA

MARCH 26, 2021

A meeting scheduled for May 8 of the Cellular, Tissue and Gene Therapies Advisory Committee was slated to be a hybrid event – with members of the committee participating virtually and FDA staff appearing onsite at the agency campus, but was altered to become an all-virtual event via Adobe Connect.

Vaccination 96

Vaccination Vaccine Cardiology Gene Therapy 96

pharmaphorum

AUGUST 13, 2020

Adding in Regeneron’s antibody resulted in a 49% drop in cholesterol levels from the start of the study compared to patients sticking with their current therapy alone, according to results presented earlier this year at the American College of Cardiology’ congress in March.

Drugs 52

Drugs Antibody Sales Cardiology 52

Scienmag

AUGUST 11, 2020

New study identifies frequency of hormone therapy use and predictors of its use in women who underwent preventive oophorectomy as a result of carrying the BRCA gene CLEVELAND, Ohio (August 12, 2020)–Removal of the ovaries before natural menopause (surgical menopause) often exacerbates menopause symptoms and places women at increased risk for (..)

Hormones 43

Hormones Gene Cardiology Medicine 43

The Pharma Data

FEBRUARY 21, 2022

Our leadership in cardiology, radiology and women’s health is recognized worldwide, and we are expanding our presence in oncology, working tirelessly to bring forward new approaches that can change the treatment paradigm for patients,” said Stefan Oelrich, Member of the Board of Management, Bayer AG and President of Bayer’s Pharmaceuticals Division.

Radiology 52

Radiology Cardiology Development Production 52

XTalks

FEBRUARY 16, 2024

Related: Vyjuvek Gets FDA Nod as First Topical Gene Therapy for Rare Skin Disease The active ingredient in Aurlumyn is iloprost, a vasodilator that opens up blood vessels and stops blood from clotting. Blisters, which can affect all layers of skin, typically form 24 hours after exposure and tissue turns black if it starts dying.

Cardiology 59

Cardiology Gene Therapy Drugs Branding 59

The Pharma Data

JANUARY 21, 2021

“While we can’t control our genes, this study gives us more data to promote lifestyle changes early on and have numbers to back us up.” 20 in the journal JAMA Cardiology. 20 in the journal JAMA Cardiology. ” Mora agreed. ” The report was published online Jan. © 2021 HealthDay. .”

Insulin 52

Insulin Cardiology Research Doctor 52

The Pharma Data

MAY 31, 2022

The Company’s cell+gene platform harnesses the power of cells to create new medicines for neurology, cardiology, immunology, and ophthalmology indications.

Trials 52

Trials Engineer Clinical Trials Clinical Trials 52

Pharma Marketing Network

FEBRUARY 27, 2025

Scientific blogs discussing new advancements in oncology, cardiology, or rare diseases. For example, a LinkedIn article on the future of gene therapy can position a brand as an authority in genetic medicine, attracting biotech investors, researchers, and prescribing physicians.

Branding 52

Branding Marketing Compliance Pharma Companies 52

The Pharma Data

SEPTEMBER 15, 2020

Pfizer’s Rare Disease late-stage pipeline currently includes three gene therapy programs that, if successful, are expected to gain regulatory approval by the end of 2023, with an additional pipeline of 10 preclinical initiatives that are at various stages of maturity. and -50.4%

Gene Therapy 52

Gene Therapy Vaccination Vaccine Trials 52

Scienmag

MAY 18, 2021

Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the […].

Bacteria 74

Bacteria Genetics Scientist Gene 74

Scienmag

FEBRUARY 10, 2021

Data demonstrates new increased diversity in genetic studies and provides new insights into population-specific diseases Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority (..)

Genetics 71

Genetics Research Medicine Bioinformatics 71

Scienmag

NOVEMBER 19, 2020

Precise treatment leads to resolution of patient’s debilitating symptoms and complete remodeling of her lymphatic system Philadelphia, November 20, 2020–Researchers at Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, (..)

Research 67

Research Gene Cardiology Genetics 67

Scienmag

OCTOBER 15, 2020

Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)

DNA 54

DNA Genetics Scientist Research 54

Scienmag

SEPTEMBER 8, 2020

Salk study is the first to reveal ways cells from the human circulatory system change with age and age-related diseases Credit: Bersini, Schulte et al.

Scientist 54

Scientist Gerontology Gene Cardiology 54

Scienmag

APRIL 28, 2021

Credit: Unsplash Whether you hanker for a hard hit of caffeine or favour the frothiness of a milky cappuccino, your regular coffee order could be telling you more about your cardio health than you think. In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […].

Genetics 52

Genetics Research Gene Cardiology 52