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First hybrid gene therapy shows early promise in treating long QT syndrome

Scienmag

— In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. ROCHESTER, Minn.

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Research identifies new cause of heart failure condition in children

Medical Xpress

In an effort to determine the cause behind a rare condition that causes heart failure in children, University of Maryland School of Medicine (UMSOM) researchers have identified new gene mutations responsible for the disorder in an infant patient.

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New mutation raises risk for AFib, heart failure for people of color

Scienmag

Study published in JAMA Cardiology Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

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Many genes associated with the risk of coronary artery disease act through the liver

Scienmag

According to a new study published in The American Journal of Human Genetics, more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. These variants have an impact on the expression of genes regulating cholesterol metabolism, among other things. […].

Gene 52
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Advancing gene editing with new CRISPR/Cas9 variant

Scienmag

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say. Eugene Chen, M.D., […].

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New insight into a placental gene pathway and its association with vitamin D

Scienmag

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

Gene 52
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How Phosphorus’ GeneCompass Preventative Genetic Test Can Help People Manage Their Health

XTalks

The test’s NGS technology achieves a clinical specificity of over 99 percent per condition and the test can detect over 99 percent of potential variants in each gene. As a preventative tool, the test can assist people in taking early action to help mitigate and even prevent health problems.