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An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years. The breakthrough, published in Cardiovascular Research and led by scientists at the University of Bristol and the MultiMedica Group in Italy, offers a potential target for patients with heart failure.
Independent of cholesterol, gene variants raise risk of heart disease, diabetes, high blood pressure Credit: In-Hyuk Jung, PhD, Stitziel Lab High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.
Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (..)
Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the […].
Adding in Regeneron’s antibody resulted in a 49% drop in cholesterol levels from the start of the study compared to patients sticking with their current therapy alone, according to results presented earlier this year at the American College of Cardiology’ congress in March.
LA JOLLA–(September 8, 2020) Salk scientists have used skin cells called fibroblasts from young and old patients to successfully create blood vessels cells that retain their molecular […].
Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)
Team led by scientists at Cincinnati Children’s discover molecular process behind dangerous loss of heart muscle Credit: Cincinnati Children’s In many situations, heart muscle cells do not respond to external stresses in the same ways that skeletal muscle cells do.
Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.
Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A. 2022 was the first year on market for cell-based gene therapies Abecma (Idecabtagene vicleucel) and Breyanzi (lisocabtagene maraleucel) , which generated $388 million and $182 million, respectively. Both are anti-CD20 agents.
Hal will become the Board’s third designated Scientific and Medical Expert alongside Dr Jesse Goodman, former Chief Scientist at the US FDA, and Dr Laurie Glimcher, President and CEO of the Dana-Farber Cancer Institute. Dr Dietz completed his BS at Duke University and received his MD from the SUNY Upstate School of Medicine.
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