Scienmag

MARCH 25, 2021

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (..)

Genetics 75

Genetics Gene Scientist Research 75

Scienmag

FEBRUARY 17, 2021

Credit: Mark Bauer/FSU College of Medicine Nearly a half-million people a year die from sudden cardiac death (SCD) in the U.S. A leading cause of SCD in young athletes is arrhythmogenic cardiomyopathy (ACM), a genetic disease in which healthy heart muscle is replaced over time […].

Medicine 55

Medicine Genetic Disease Development Genetics 55

Scienmag

DECEMBER 3, 2020

Associated collaboration with the New York Genome Center to expand patient access to advanced genomic technologies Seeking to advance the scope of precision medicine, Weill Cornell Medicine, NewYork-Presbyterian Hospital, and Illumina, Inc.

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Genome Genomics Medicine Genetics 52

Scienmag

MARCH 31, 2021

But now, scientists at Washington University School of Medicine in St. […].

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Scienmag

MAY 5, 2021

Study published in JAMA Cardiology Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

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Cardiology Genetics Gene Research 53

Scienmag

APRIL 28, 2021

In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […].

Genetics 52

Genetics Research Gene Cardiology 52

Scienmag

JUNE 3, 2021

Conducted in partnership with the University of Reading, the world-first study used a genetic-approach to investigate causal […].

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Scienmag

AUGUST 20, 2020

In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can […]. (..)

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Genetics Gene Genome Genomics 41

FDA Law Blog

NOVEMBER 10, 2024

These have included clinical trials for rare diseases across metabolic (n=5), oncology (n=5), cardiology (n=3), dermatology (n=3), pulmonary (n=3), hematology (n=2), hepatology (n=2), ocular (n=2), transplant (n=1), gastrointestinal (n=1), immunology (n=1), infectious (n=1), neurology (n=1), orthopedic (n=1), and toxicology (n=1) indications.

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Production Clinical Development Development Regulation 69

Scienmag

AUGUST 31, 2020

Sophia Antipolis, France – 31 Aug 2020: Losing weight could prevent or even reverse diabetes, according to late breaking research presented today at ESC Congress 2020.1 In 2019, approximately 463 million people worldwide had diabetes, of which the vast majority (around 90%) was type 2 diabetes.2

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Scienmag

NOVEMBER 25, 2020

Gerszten, MD, Chief of the Division of Cardiovascular Medicine at Beth Israel Deaconess Medical Center (BIDMC) […]. . – Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren’t sure why some people experience mild to no symptoms while others become critically ill.

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Scienmag

NOVEMBER 18, 2020

— Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. ROCHESTER, Minn. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease ?

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Genetics RNA Protein Research 40

Scienmag

SEPTEMBER 7, 2020

Credit: Felix Petermann, MDC Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

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Medicine Research Bioinformatics Allergies 58

Scienmag

APRIL 20, 2021

Researchers at Penn Medicine uncover more genetic mutations that predispose women to peripartum cardiomyopathy, with implications for the future of increased genetic testing PHILADELPHIA– Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), (..)

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Genetics Development Medicine Research 45

Scienmag

MAY 18, 2021

Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the […].

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Bacteria Genetics Scientist Gene 74

The Pharma Data

OCTOBER 28, 2020

28, 2020 — There may be a positive causal relationship between elevated birth weight and risk for future atrial fibrillation in adulthood, according to a study presented at the annual Great Wall International Congress of Cardiology, held virtually from Oct. WEDNESDAY, Oct. The genome-wide association study included 321,223 individuals.

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Cardiology Genetics Genome Genomics 40

Scienmag

FEBRUARY 17, 2021

In a world first genetic study, researchers from the Australian Centre for Precision Health at the University of South Australia found that that long-term, […].

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Genetics Research Cardiology Medicine 65

The Pharma Data

OCTOBER 22, 2020

Pre-pregnancy care for a woman with known aortic disease would include evaluation of maternal and fetal risk, counseling and possible genetic testing, followed by ongoing monitoring and testing, study co-author Dr. Melinda Davis, a cardio-obstetrics expert at University of Michigan Medicine, said in a university news release.

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Cardiology Hormones Genetics Research 52

Scienmag

FEBRUARY 24, 2021

According to a new study published in The American Journal of Human Genetics, more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. Credit: UEF/Raija Törrönen.

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Gene Genetics Regulation Cardiology 52

Scienmag

DECEMBER 3, 2020

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say. Eugene Chen, M.D., […].

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Gene Editing Gene DNA Genetics 41

Scienmag

OCTOBER 15, 2020

Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)

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DNA Genetics Scientist Research 54

Scienmag

DECEMBER 3, 2020

In a randomized, controlled clinical trial, researchers found that patients who received genetic test results about the side effects of cholesterol-lowering medications did not have worse outcomes after one year A person’s genetic make-up can influence whether they might experience side effects from certain medications.

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Scienmag

FEBRUARY 7, 2021

The study, published in the European Journal of Internal Medicine, is the first of its kind to focus on the […].

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Scienmag

MAY 17, 2021

Patients’ genetic profile strongly influences size of effect in early-phase trial People with extremely high levels of triglycerides (a type of fat in the blood) and a specific genetic profile saw a substantial reduction in triglycerides after taking the human monoclonal antibody evinacumab compared with those taking a placebo, in a study presented (..)

Genetics 42

Genetics Antibody Trials Gene Therapy 42

The Pharma Data

AUGUST 30, 2021

Wilson disease is a rare and progressive genetic condition in which the body’s pathway for removing excess copper is compromised. ALXN1840, a potential new once-daily, oral medicine, demonstrated approximately three times greater copper mobilisation than SoC. Wilson disease. 1 It affects one in 30,000 live births in the US.

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Trials Genetics Cardiology Medicine 52

XTalks

JANUARY 3, 2025

FCS is a rare genetic disorder that prevents the body from properly breaking down triglycerides (a type of fat in the blood), leading to dangerously high levels. This can result in acute pancreatitis (inflammation of the pancreas), a life-threatening condition causing severe abdominal pain and other health complications.

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Scienmag

JANUARY 14, 2021

14, 2021 — Adults who smoke or who are genetically predisposed to smoking behaviors are more likely to experience a serious type of stroke called subarachnoid hemorrhage (SAH), according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. […].

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Genetics Research Cardiology Medicine 46

The Pharma Data

DECEMBER 8, 2020

The company’s commercial priorities are three-fold: (1) Initially focusing its commercial efforts on rare diseases within its prolific neurology and cardiology franchises (2) pioneer new markets where there are no available treatments (3) create new standards of care where there has been a lack of innovation to optimize patient care. .

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Pharma Marketing Network

FEBRUARY 27, 2025

Scientific blogs discussing new advancements in oncology, cardiology, or rare diseases. A live Q&A on precision medicine in oncology can attract oncologists looking for updated treatment protocols. Publish thought leadership articles on digital health, AI in pharma, or precision medicine.

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The Pharma Data

JANUARY 5, 2021

.” “They are frequently hospitalized and often undergo multiple invasive procedures or surgeries early in childhood and throughout their lifetime,” said Dr. Vincent Gonzalez, a pediatric cardiology fellow at Baylor College of Medicine/Texas Children’s Hospital in Houston.

Cardiology 52

Cardiology Doctor Doctors Genetics 52

Delveinsight

DECEMBER 29, 2020

X-linked myotubular myopathy (XLMTM) is a rare genetic neuromuscular disorder and leads to muscle weakness, respiratory failure, and early death. The ASPIRO trial is a two-part, open-label ascending dose study, and is examining the safety and preliminary efficacy of AT132 in children with XLMTM younger than five years old.

Trials 52

Trials Drugs Hormones Radiology 52

Scienmag

OCTOBER 22, 2020

Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.

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Scienmag

OCTOBER 8, 2020

M2D2 $200K Challenge provides funding, in-kind support to promising ventures LOWELL, Mass. – A medical-device startup that aims to improve the health of pregnant women is the top winner in an annual pitch contest presented by the Massachusetts Medical Device Development Center (M2D2).

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Development Clinical Trials Clinical Trials Cardiology 71

Scienmag

JUNE 17, 2021

Researchers from University of Tsukuba, Japan, collaborating with scientists from Germany, develop a mouse model for restrictive cardiomyopathy and uncover the underlying mechanisms of the disease Ibaraki, Japan – Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that (..)

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Scienmag

NOVEMBER 19, 2020

Precise treatment leads to resolution of patient’s debilitating symptoms and complete remodeling of her lymphatic system Philadelphia, November 20, 2020–Researchers at Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, (..)

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Scienmag

SEPTEMBER 24, 2020

New light is being shed on a little-known role of Y chromosome genes, specific to males, that could explain why men suffer differently than women from various diseases, including Covid-19.

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Gene Research Cardiology Genetics 60

Scienmag

NOVEMBER 9, 2020

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

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