Medical Xpress

NOVEMBER 14, 2022

Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine (UMSOM) researchers continue to report on new findings from the landmark transplant.

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Medical Xpress

JANUARY 26, 2023

Research in a mouse model of diet-induced obesity has found greater disruption to genes involved in heart function when coupled with vitamin A deficiency using a combined dietary and genetic approach. The study is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology.

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Scienmag

MAY 5, 2021

Study published in JAMA Cardiology Credit: UIC/Jenny Fontaine A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

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Scienmag

APRIL 28, 2021

In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […].

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Scienmag

JUNE 3, 2021

Credit: Unsplash A dash of milk could make all the difference to a healthy heart as new research from the University of South Australia finds that people who regularly consume milk have a lower risk of heart disease.

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Scienmag

AUGUST 31, 2020

Sophia Antipolis, France – 31 Aug 2020: Losing weight could prevent or even reverse diabetes, according to late breaking research presented today at ESC Congress 2020.1 In 2019, approximately 463 million people worldwide had diabetes, of which the vast majority (around 90%) was type 2 diabetes.2

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Scienmag

NOVEMBER 25, 2020

New research led by Robert E. . – Even as tens of thousands of Americans test positive for COVID-19 each day, physicians still aren’t sure why some people experience mild to no symptoms while others become critically ill.

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Scienmag

DECEMBER 10, 2020

Jefferson researchers find that the genetic underpinnings of a skin disorder at birth indicate future heart problems PHILADELPHIA – Our skin tells us when we’ve spent too much time in the sun or when the dry air of winter has sucked away too much moisture.

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Scienmag

NOVEMBER 18, 2020

— Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. ROCHESTER, Minn. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease ?

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Medical Xpress

FEBRUARY 6, 2023

A genetic score may be able to identify higher stroke risk—but only for people living in the most privileged neighborhoods, according to new research that highlights inequities related to wealth and health.

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Scienmag

FEBRUARY 17, 2021

A leading cause of SCD in young athletes is arrhythmogenic cardiomyopathy (ACM), a genetic disease in which healthy heart muscle is replaced over time […]. Credit: Mark Bauer/FSU College of Medicine Nearly a half-million people a year die from sudden cardiac death (SCD) in the U.S.

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Scienmag

FEBRUARY 17, 2021

In a world first genetic study, researchers from the Australian Centre for Precision Health at the University of South Australia found that that long-term, […].

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Scienmag

NOVEMBER 19, 2020

Precise treatment leads to resolution of patient’s debilitating symptoms and complete remodeling of her lymphatic system Philadelphia, November 20, 2020–Researchers at Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, (..)

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Scienmag

FEBRUARY 7, 2021

Beer-Sheva, Israel…February 8, 2021 – A new discovery by researchers from Ben-Gurion University of the Negev (BGU) and its affiliated Soroka University Medical Center shows that medical cannabis may reduce blood pressure in older adults.

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The Pharma Data

OCTOBER 22, 2020

22, 2020 — Pregnancy can increase the risk of a rare, dangerous heart condition called aortic dissection, researchers report. Researchers analyzed data from 29 women who were unexpectedly hospitalized for aortic dissection while pregnant. 14 in the journal JAMA Cardiology. THURSDAY, Oct. Patients require lifesaving care.

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Scienmag

APRIL 20, 2021

Researchers at Penn Medicine uncover more genetic mutations that predispose women to peripartum cardiomyopathy, with implications for the future of increased genetic testing PHILADELPHIA– Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), (..)

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Scienmag

OCTOBER 15, 2020

Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)

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The Pharma Data

OCTOBER 28, 2020

28, 2020 — There may be a positive causal relationship between elevated birth weight and risk for future atrial fibrillation in adulthood, according to a study presented at the annual Great Wall International Congress of Cardiology, held virtually from Oct. WEDNESDAY, Oct. The genome-wide association study included 321,223 individuals.

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Scienmag

DECEMBER 3, 2020

In a randomized, controlled clinical trial, researchers found that patients who received genetic test results about the side effects of cholesterol-lowering medications did not have worse outcomes after one year A person’s genetic make-up can influence whether they might experience side effects from certain medications.

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XTalks

APRIL 15, 2021

Dr. Benoit Tyl, MD, FESC, medical and scientific director, cardiology at Servier, says that the disconnect between correlation and causality in cardiovascular disease trials is partially responsible for the lack of approved HFpEF therapies. Figure 1: The use of Mendelian randomization to validate genetic drug targets.

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Scienmag

JANUARY 14, 2021

14, 2021 — Adults who smoke or who are genetically predisposed to smoking behaviors are more likely to experience a serious type of stroke called subarachnoid hemorrhage (SAH), according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. […].

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Scienmag

DECEMBER 3, 2020

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say. Eugene Chen, M.D., […].

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XTalks

SEPTEMBER 4, 2024

The data, presented at the European Society of Cardiology Congress 2024, suggest that vutrisiran could significantly reduce the risk of death and heart-related issues, marking a potential treatment breakthrough.

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FDA Law Blog

NOVEMBER 10, 2024

Background on the Grants Program Launched as part of the Orphan Drug Act of 1983, this program aims to encourage research and development of drugs, biologics, medical devices, and medical foods for rare diseases, defined as conditions that affect fewer than 200,000 people in the U.S. The seven awardees included six early-stage trials (e.g.,

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The Pharma Data

JANUARY 5, 2021

For the study, the researchers reviewed medical records of close to 119,000 kids, aged 4 to 17, who were treated at Texas Children’s Hospital in Houston more than once between 2011 and 2016. The defects range from mild to severe and sometimes require immediate or multiple surgeries. Of those, 1,164 had congenital heart disease.

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Scienmag

OCTOBER 22, 2020

Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.

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The Pharma Data

AUGUST 30, 2021

Wilson disease is a rare and progressive genetic condition in which the body’s pathway for removing excess copper is compromised. Wilson disease is a rare and progressive genetic condition in which the body’s pathway for removing excess copper is compromised. Wilson disease. 1 It affects one in 30,000 live births in the US.

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Scienmag

JUNE 17, 2021

Researchers from University of Tsukuba, Japan, collaborating with scientists from Germany, develop a mouse model for restrictive cardiomyopathy and uncover the underlying mechanisms of the disease Ibaraki, Japan – Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that (..)

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Scienmag

SEPTEMBER 7, 2020

Credit: Felix Petermann, MDC Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

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Scienmag

SEPTEMBER 24, 2020

The findings were published this month in Scientific Reports by Université de Montréal professor Christian Deschepper, director of the Experimental Cardiovascular Biology research unit of […].

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Scienmag

NOVEMBER 9, 2020

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

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Scienmag

OCTOBER 7, 2020

What could researchers learn by following hundreds of […].

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Scienmag

AUGUST 7, 2020

Research points to potential to reduce triglyceride levels without the risk of unpleasant and serious side effects in the intestines and liver Credit: Image is courtesy of Navid Marvi.

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The Pharma Data

DECEMBER 8, 2020

The company’s commercial priorities are three-fold: (1) Initially focusing its commercial efforts on rare diseases within its prolific neurology and cardiology franchises (2) pioneer new markets where there are no available treatments (3) create new standards of care where there has been a lack of innovation to optimize patient care.

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The Pharma Data

AUGUST 30, 2021

Results were presented at the ESC Congress 2021, organized by the European Society of Cardiology (ESC). In the first analysis, patients with established CeVD treated with Leqvio achieved an average 55.2% reduction in LDL-C from baseline to Day 510 compared with placebo ( P < 0001) 1. a statin or ezetimibe).

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The Pharma Data

SEPTEMBER 15, 2020

I am proud of the truly transformational science that our research and clinical teams are bringing to the fight against disease, as well as the unprecedented speed with which we are advancing our clinical programs in the battle against COVID-19. THERAPEUTIC AREAS OF FOCUS. and -50.4%

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XTalks

SEPTEMBER 11, 2024

Women encounter specific health issues that require specialized research and healthcare solutions, ranging from breast cancer to endometriosis. Despite advancements in medical research, women’s health has historically been underrepresented and underfunded, leading to disparities in treatment efficacy and safety for women.

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