Scienmag

MAY 13, 2021

Clinicians and scientists have long observed that cells in overstressed hearts have high levels of the simple sugar O-GlcNAc modifying thousands of proteins within cells.

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Protein Scientist Medicine Research 40

The Pharma Data

NOVEMBER 30, 2020

. “It’s well known that diet plays a critically important role in the development of heart disease and stroke,” said Dr. Amit Khera, professor of medicine and director of the preventive cardiology program at the University of Texas Southwestern Medical Center in Dallas. According to AHA statistics, an estimated 6.2

Cardiology 52

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Scienmag

JANUARY 15, 2021

Scientific Reports publishes the first study to analyze the relationships among proteomic signatures, religion and spirituality and risk of developing a clinical condition BOSTON – The Study on Stress, Spirituality and Health (SSSH), a cutting-edge proteomics analysis, suggests that religious beliefs modulate protein expression associated with (..)

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Protein Development Cardiology Medicine 58

The Pharma Data

NOVEMBER 9, 2020

For the new study, researchers focused on American Indians, “a special population that, unfortunately, is not always included in studies that show the benefit of physical activity,” said the lead researcher Dr. Ozan Unlu, chief resident of quality and patient safety at Weill Cornell Medicine in New York City.

Medicine 52

Medicine Cardiology Research Protein 52

Scienmag

APRIL 28, 2021

For the first time, researchers have identified the specific mechanism of von Willebrand Factor (vWF) — an essential blood clotting protein — that enables it to bind to platelets and initiate clotting Under normal, healthy circulatory conditions, the von Willebrand Factor (vWF) keeps to itself.

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Scientist Protein Drugs Research 53

Scienmag

OCTOBER 7, 2020

Collaborative projects funded by the awards will address important questions about neurodegenerative disease, nucleus biology, and protein turnover Credit: Dollie LaJoie, Huntsman Cancer Institute at the University of Utah Could scientists detect neurodegenerative diseases like Alzheimer’s and ALS years or decades before these disorders manifest (..)

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Protein Scientist Research Cardiology 52

Scienmag

DECEMBER 18, 2020

Scientists made the finding by running fluid spiked with a COVID-19-like protein through a 3D-printed model of the arteries of a patient who had suffered […].

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Protein Scientist Cardiology Medicine 52

The Pharma Data

MARCH 17, 2022

The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on haematology, nephrology, neurology, metabolic disorders, cardiology and ophthalmology.

Cardiology 52

Cardiology Medicine Development Protein 52

Scienmag

NOVEMBER 18, 2020

This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease ? and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. Dilated cardiomyopathy […].

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Genetics RNA Protein Research 40

The Pharma Data

APRIL 28, 2022

Patients could stay on stable standard of care medicines, with a few exceptions, for the duration of the randomised control period. The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. Source link: [link].

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Antibody Trials Medicine Cardiology 52

Scienmag

MAY 18, 2021

Predictions from this […].

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Protein Research Cardiology Engineer 43

The Pharma Data

SEPTEMBER 5, 2021

The approval follows the recommendation of the Committee for Medicinal Products for Human Use of the European Medicines Agency in July 2021. The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system.

Clinical Trials 52

Clinical Trials Clinical Trials Cardiology Medicine 52

XTalks

JANUARY 3, 2025

Tryngolza works by targeting a protein in the liver, apoC-III, which regulates triglyceride metabolism. People with FCS often have triglyceride levels higher than 880 mg/dL, compared to a healthy target level of below 150 mg/dL. FCS also severely impacts quality of life, causing chronic fatigue and recurrent stomach pain.

FDA Approval 59

FDA Approval Drugs Clinical Trials Clinical Trials 59

The Pharma Data

DECEMBER 8, 2020

The company’s commercial priorities are three-fold: (1) Initially focusing its commercial efforts on rare diseases within its prolific neurology and cardiology franchises (2) pioneer new markets where there are no available treatments (3) create new standards of care where there has been a lack of innovation to optimize patient care. .

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Medicine RNA Production Marketing 52

Scienmag

SEPTEMBER 15, 2020

Circulation: Cardiovascular Imaging Journal report DALLAS, September 15, 2020 — Patients with psoriasis treated with biologic therapy, which are protein-based infusions to suppress inflammation, had a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research published today in Circulation: Cardiovascular (..)

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Protein Research Cardiology Medicine 40

Scienmag

SEPTEMBER 2, 2020

A particular protein triggers a part of our immune system that can boost the blood’s tendency to coagulate and form clots. Why so many COVID-19 patients get blood clots (thrombosis) remains uncertain. But scientists at Uppsala University and the University Hospital have now identified a mechanism they believe to be implicated.

Protein 40

Protein Scientist Allergies Cardiology 40

The Pharma Data

AUGUST 22, 2021

The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on haematology, nephrology, neurology, metabolic disorders, cardiology, and ophthalmology.

Trials 52

Trials Clinical Trials Clinical Trials Cardiology 52

The Pharma Data

APRIL 4, 2023

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency based its positive opinion on results from the CHAMPION-NMOSD Phase III trial. 2,3 Approximately three-quarters of people with NMOSD are anti-AQP4 Ab+, meaning they produce antibodies that bind to a specific protein, aquaporin-4 (AQP4).

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Trials Medicine Antibody Clinical Trials 40

XTalks

AUGUST 2, 2023

With each passing year, pharmaceutical companies around the globe strive to deliver cutting-edge medicines, therapies and vaccines that impact the lives of millions. In this in-depth article, we embark on a captivating journey to uncover the top 30 pharma and biotech companies that have been instrumental in shaping the future of medicine.

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Sales Manufacturing FDA Approval Life Science 98

The Pharma Data

NOVEMBER 4, 2020

The antibody is designed to bind to misfolded light chain protein and amyloid and shows binding to both kappa and lambda subtypes. Food and Drug Administration and European Medicine Agency as a potential therapy for patients with AL amyloidosis. CAEL-101 has received Orphan Drug Designation from both the U.S. About AL Amyloidosis.

Antibody 52

Antibody Containment Clinical Trials Clinical Trials 52

The Pharma Data

NOVEMBER 4, 2020

The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. The medication works by inhibiting the C5 protein in the terminal complement cascade, a part of the body’s immune system. About ULTOMIRIS ®. About SOLIRIS ®. INDICATIONS. What is ULTOMIRIS? INDICATIONS.

Doctors 52

Doctors Doctor Vaccination Vaccine 52

The Pharma Data

SEPTEMBER 15, 2020

20vPnC showed a safety and tolerability profile that was similar to Prevnar 13 ® Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]. Internal Medicine. Based on the acceptable safety profile and the favorable immune response data, including the 4th dose response data, Pfizer received Breakthrough Therapy Designation.

Gene Therapy 52

Gene Therapy Vaccination Vaccine Trials 52

Scienmag

JULY 19, 2021

May also explain liver fat differences among men & women Credit: Sallam Lab/UCLA FINDINGS A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells’ protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver (..)

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RNA DNA Genetics Protein 95

The Pharma Data

MAY 13, 2021

The Yale Journal of Biology and Medicine. Preventive Medicine Reports. Experimental & Molecular Medicine. Journal of addiction medicine. Journal of the American College of Cardiology. Neuroendocrinology of obesity. Br Med Bull. 2014;109:73-82. DOI: 10.1093/bmb/ldu001. . 2012;85(3):405-414. PMID: 23012588 .

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Insulin Production Hormones Medicine 52