Pharmaceutical Technology

JULY 8, 2024

Myricx Bio has secured £90m ($114m) in its Series A financing round to propel its NMTi-ADC therapeutics into the clinical development stage.

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Development Clinical Development 264

XTalks

JUNE 4, 2024

In the ever-evolving landscape of pharmaceutical development, the complexity of early phase clinical trials is increasing. This surge in complexity is driven by escalating drug development costs, heightened competition and advanced scientific innovations. And that has a lot of downstream consequences.” This trend, which Dr.

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Clinical Development Development Clinical Trials Clinical Trials 91

pharmaphorum

JANUARY 10, 2024

Ensuring R&D investments deliver maximum potential: Notable ways to enhance clinical development strategy and design Mike.Hammerton Wed, 10/01/2024 - 11:23 Bookmark this

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Clinical Development Development 118

pharmaphorum

MARCH 7, 2024

Digital tools must be used in pharma manufacturing to keep pace with drug discovery and clinical development Mike.Hammerton Thu, 07/03/2024 - 09:43 Bookmark this

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Clinical Development Manufacturing Development Drugs 113

XTalks

MAY 28, 2024

Our discussion delved into the potential of DHTs to reshape how clinical trials are conducted, making them not only faster and less costly but also more patient-centric and reflective of real-world outcomes. This approach can speed up development and improve data quality, potentially leading to more effective and personalized therapies.

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Clinical Development Development Clinical Trials Clinical Trials 110

Pharmaceutical Technology

JULY 12, 2022

The post Acute lymphocytic leukaemia leads in cell therapy clinical development appeared first on Pharmaceutical Technology. Despite the market size for B-cell non-Hodgkin’s lymphoma (NHL) being at least five times that of ALL, NHL has a smaller pipeline of cell therapies.

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Clinical Development Development Production Sales 130

CTTI (Clinical Trials Transformation Initiative)

OCTOBER 15, 2024

The Potential of Disease Progression Modeling to Advance Clinical Development and Decision Making The post The Potential of Disease Progression Modeling to Advance Clinical Development and Decision Making appeared first on CTTI.

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Pharmaceutical Technology

SEPTEMBER 5, 2024

ArsenalBio has secured $325m in a Series C financing round to propel its programmable cell therapy programmes through clinical development.

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Development Clinical Development 130

Pharmaceutical Technology

JUNE 9, 2023

It is also preparing for a swift transition to Phase III development. Upstream Bio will use the funds to advance its UPB-101 into Phase II trials to treat asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). It targets the human thymic stromal lymphopoietin receptor to inhibit signalling.

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Clinical Development Development Life Science Clinical Trials 147

Outsourcing Pharma

JANUARY 9, 2024

Equally, OSP was delighted to speak to him to discuss the evolution of data management in clinical development and how intelligent data use can reduce clinical trial cancellations, minimise protocol amendments, and accelerate patient recruitment. Gen Li is president and founder of Phesi.

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Clinical Development Development Clinical Trials Clinical Trials 59

Outsourcing Pharma

APRIL 7, 2022

Experts from the Decentralized Trials and Research Alliance and Rafael Pharmaceuticals discuss progress and possibilities during Clinical Development Advances.

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Clinical Development Development Trials Research 75

FDA Law Blog

NOVEMBER 10, 2024

Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.

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Production Clinical Development Development Regulation 67

Medical Xpress

APRIL 26, 2023

A successful gene therapy trialed at Michigan State University in dogs with an inherited eye disease is ready to be developed for clinical use in human patients with a rare condition called retinitis pigmentosa.

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Clinical Development Gene Therapy Development Gene 133

Pharma Mirror

JUNE 23, 2021

Vectura Group plc, an industry leading inhalation CDMO, today announced it has signed an agreement with Incannex Healthcare Limited, an Australian cannabinoid medicines development company, to provide pre-clinical development services for IHL-216A, Incannex’s proprietary inhaled drug product for the treatment of traumatic brain injury (TBI).

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Clinical Development Development Manufacturing Medicine 130

Pharmaceutical Technology

MAY 22, 2024

AltruBio has secured $225m in an oversubscribed Series B financing round to propel the clinical development of its ICE programme.

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Development Clinical Development 130

Advarra

OCTOBER 4, 2023

When it comes to clinical development, precision, compliance, and quality assurance are paramount. For clinical development organizations, an effective CAPA serves as an essential compass, directing a path towards continuous improvement while maintaining steadfast regulatory compliance.

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Compliance Clinical Development Development Clinical Trials 52

BioSpace

JULY 22, 2021

Shares of Adverum Biotechnologies plunged more than 20% in premarket trading after the company announced it was revising its clinical development plan for investigational gene therapy candidate ADVM-022 based on safety concerns in patients with diabetic macular edema (DME).

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Gene Therapy Clinical Development Gene Development 96

Fierce Pharma

OCTOBER 26, 2023

By Thomas Pietsch, Global Head of Scientific Data Technology and AI, Parexel International | AI holds unlimited potential to change today’s clinical development paradigm. Explore three broad areas where it could be especially useful today.

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Clinical Development Development 57

Pharma Mirror

FEBRUARY 25, 2022

This joint service offering, DRIVE™-Biologics, will leverage Abzena’s strength in design and developability, and cell line development through to commercial manufacturing.

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Clinical Development Development Manufacturing Medicine 130

Pharmaceutical Technology

MARCH 4, 2024

FogPharma has secured $145m in a Series E financing round to support the clinical development of its cancer therapy, FOG-001.

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Development Clinical Development 130

Scienmag

JULY 19, 2022

July 19, 2022, New York—Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI) driven drug discovery company, has appointed Dr. Sujata Rao as Senior Vice President (SVP) with responsibility for the global clinical development strategy of Insilico Medicine’s therapeutic programs.

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Clinical Development Medicine Development Drugs 83

Outsourcing Pharma

SEPTEMBER 12, 2024

Recent investments by major pharmaceutical companies signal a growing confidence in artificial intelligenceâs (AI's) potential to transform drug development.

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Clinical Development Development Drugs 59

Pharma Times

JULY 9, 2024

Myricx Bio’s therapies include treatments for breast, lung and colorectal cancer

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Clinical Development Development 145

Pharmaceutical Technology

APRIL 3, 2023

Ablaze Pharmaceuticals is set to develop a new GPC3-targeted peptide drug candidate for the treatment of liver cancer in China. The agreement allows Ablaze to clinically develop and commercialise the drug in Greater China. The company is licensing the first-in-class drug candidate under an existing deal with RayzeBio.

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Development Drugs Clinical Development Licensing 246

Outsourcing Pharma

MAY 9, 2023

Xequel Bio has selected Societal CDMO to support the ongoing clinical development of a patented new chemical entity based on its aCT1 (alpha-Connexin carboxyl-Terminal 1 peptide) platform.

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Clinical Development Development Contract Manufacturing Manufacturing 52

XTalks

NOVEMBER 1, 2023

Stephanie Manson Brown, VP & Head of Clinical Development & Scientific Innovation of R&D at Allergan Aesthetics at AbbVie. She also spoke about clinical trials in the space, including Allergan Aesthetics’ commitment to increasing diversity in trials and developing products that do not cater to any one beauty standard.

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Life Science Clinical Trials Clinical Trials Clinical Development 93

Pharmaceutical Technology

OCTOBER 2, 2024

The funds will support the development of LoQus23’s lead candidate, its MutSβ inhibitor, as it enters clinical development.

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Clinical Development Development 264

Pharmaceutical Technology

NOVEMBER 14, 2023

MBrace Therapeutics has secured $85m in a Series B funding round to advance clinical development of ADCs for oncology targets.

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Development Clinical Development 130

Pharmaceutical Technology

AUGUST 24, 2023

FORE Biotherapeutics has raised $75m in its Series D investment round led by SR One to expedite the clinical development of plixorafenib.

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Development Clinical Development 130

BioSpace

SEPTEMBER 15, 2020

Clinical-stage biopharmaceutical firm ESCAPE Bio has snagged a $73 million crossover financing deal, led by Wellington Management Company, which will help advance the company’s two clinical development programs of precision neurology medicines for patients with genetic neurodegeneration.

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Clinical Development Development Genetics Medicine 89

Pharmaceutical Technology

MAY 17, 2023

Chinook Therapeutics and Ionis Pharmaceuticals have entered a partnership to develop an antisense oligonucleotide (ASO) therapy to treat a rare, severe chronic kidney disease. The collaboration aims to discover, develop and commercialise an ASO therapy.

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Development Protein RNA Genetics 246

Pharmaceutical Technology

OCTOBER 21, 2022

Hookipa Pharma and Roche have signed a strategic partnership and licence agreement for developing HB-700 and another undisclosed arenaviral immunotherapy. Under the deal, Hookipa will carry out research and initial clinical development through Phase Ib for HB-700 to treat KRAS-mutated cancers.

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Development Production Licensing Licensing 278

Pharmaceutical Technology

OCTOBER 28, 2022

Drug discovery and development is an incredibly expensive and time-consuming process, taking between 12 and 18 years, and costing on average between $2 billion and $3 billion. Robots can improve drug discovery and development. Lab-specific industrial co-bots can carry out both complex and repetitive tasks such as liquid handling.

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Development Drugs Pharma Companies Life Science 311

Pharmaceutical Technology

AUGUST 2, 2023

The grant will support the early development of Amygdala’s ALDH2 Inhibitor currently in pre-clinical development.

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Development Clinical Development 130

Pharmaceutical Technology

OCTOBER 25, 2022

Ast ellas Pharma has announced plans to make a strategic investment to back the development of Taysha Gene Therapies’ adeno-associated virus (AAV) development programmes for Rett syndrome and giant axonal neuropathy (GAN). This would allow the companies to boost the development of new therapy options for Rett syndrome and GAN patients.

Gene Therapy 264

Gene Therapy Gene Development Genetics 264

Pharmaceutical Technology

OCTOBER 14, 2022

German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs.

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Vaccination Vaccine Development Immune Response 289