XTalks

SEPTEMBER 5, 2023

Vaccines have been an integral piece of the global public health toolbox for over 200 years, but the COVID-19 pandemic brought about a new era in vaccine development with renewed interest in mRNA technology and unprecedented accelerated regulatory approvals. What are the major challenges you’re facing right now in vaccine development?

Vaccination 96

Vaccination Vaccine Development Clinical Trials 96

pharmaphorum

APRIL 12, 2022

Separating the amount of antibiotic used from the payment model could entice pharma companies – who have abandoned antimicrobial R&D in their drives in the last decades – to enter the category once again and help to develop new drugs that will tackle the pressing issue of antimicrobial resistance (AMR).

Pharma Companies 119

Pharma Companies Development Drugs Medicine 119

Outsourcing Pharma

MARCH 14, 2022

The pharma company and academic institution will explore the viability of a psychedelic treatment to help patients suffering from cancer-related distress.

Pharma Companies 122

Pharma Companies Clinical Development Development 122

Outsourcing Pharma

OCTOBER 10, 2024

The big pharma company AstraZeneca has forged a licensing pact worth $2 billion with the Chinese firm CSPC Pharmaceutical Group for access to an experimental small molecule treatment for dyslipidemia.

Licensing 109

Licensing Licensing Pharma Companies Drugs 109

pharmaphorum

SEPTEMBER 3, 2020

King’s Cross is also home to Google’s DeepMind artificial intelligence company, which has already been involved in life sciences projects such as using the technology to predict acute kidney injury. She added: “Using technologies like AI is a critical part of helping us to discover and develop medicines for serious diseases.”.

Life Science 114

Life Science Scientist Engineer Pharma Companies 114

Pharmaceutical Technology

NOVEMBER 25, 2022

Pharmaceutical companies are looking to paediatric indications of approved adult dosage forms (ADFs) to sustain and fuel growth. But the challenges for drug producers developing PDFs are numerous and varied. Cambrex and its customers currently have multiple clinical and commercial PDF programs underway.

Manufacturing 130

Manufacturing Production Pharma Companies Development 130

pharmaphorum

DECEMBER 15, 2021

Going from the vital activity of patient engagement to the more encompassing state of patient centricity requires big steps in the evolution of new-drug discovery, development, and delivery. It is drug developers, patients, advocates, and caregivers in active conversations—more likely to involve clean sheets of paper than prepared scripts.

Pharma Companies 145

Pharma Companies Development Medicine Drugs 145

Outsourcing Pharma

APRIL 17, 2024

Pharma companies need to take greater ownership to make sure data quality and governance is accomplished - and it is important to keep in mind the ethics of AI use will remain front and centre for the pharma industry.

Pharma Companies 93

Pharma Companies Clinical Development Development 93

Outsourcing Pharma

JANUARY 9, 2024

Pharma company Mercaptor has announced its new âbreakthroughâ technology at J.P. Morgan HealthCare Conference which it says could transform Alzheimer's, TBI, and epilepsy treatment.

Pharma Companies 95

Pharma Companies Clinical Development Development 95

pharmaphorum

AUGUST 4, 2020

The company’s shares were valued as high as 95p on the London Stock Exchange following the announcement, the highest they had been since 2015. AstraZeneca has bought an exclusive global licence to develop and market RXC006, a porcupine inhibitor for fibrotic diseases including idiopathic pulmonary fibrosis (IPF).

Drugs 109

Drugs Clinical Trials Clinical Trials Pharma Companies 109

pharmaphorum

FEBRUARY 26, 2021

UCB and Microsoft have announced a multi-year strategic collaboration to advance the digitalisation of the Belgian pharma company and accelerate its research efforts. The companies have already been working together on the COVID Moonshot Project, which aimed to create an orally available antiviral to combat the SARS-CoV-2 coronavirus.

Drugs 97

Drugs Medicine Pharma Companies Clinical Development 97

pharmaphorum

SEPTEMBER 29, 2020

As of 2018, there were over 1,100 cancer therapies in development, and as of 2020, 362 of them were cell and gene therapies. As a result, there is a need for continued innovation and increased efficiency in terms of drug development to manage cost, complexity and speed to provide potentially transformative therapies for cancer patients.

Research 132

Research Gene Editing Development Gene 132

pharmaphorum

MAY 4, 2022

In testing new treatments, what is promising in animal models may not transfer particularly well to humans, which helps to explain why there is a 90% failure rate during clinical development. Quris has taken its technology and used it to develop its own drug candidate pipeline.

Drugs 143

Drugs Licensing Licensing Pharma Companies 143

XTalks

MAY 30, 2024

“That’s where I developed the curiosity and a desire to contribute to patient safety. Over the years, his career has evolved from routine case processing at large pharma companies to a more strategic role in smaller settings, where he feels his impact more directly. “I So, there are lots of pieces to it,” he adds.

Compliance 106

Compliance Clinical Development Pharmacy Development 106

pharmaphorum

DECEMBER 21, 2021

Novartis has joined the ranks of big pharma companies developing TIGIT-targeted drugs for cancer, and found its candidate in an existing partner, Chinese biotech BeiGene. Pharma companies are looking at whether blocking TIGIT as well as PD-1/PD-L1 can improve the efficacy of cancer immunotherapy.

Drugs 98

Drugs Antibody Pharma Companies Development 98

Outsourcing Pharma

SEPTEMBER 26, 2024

The US big pharma company Pfizer has voluntarily withdrawn the oral sickle cell disease treatment Oxbryta from the market and halted clinical trials of the drug as data indicate a high risk of severe adverse events.

Pharma Companies 76

Pharma Companies Drugs Clinical Trials Clinical Trials 76

pharmaphorum

DECEMBER 22, 2021

Gyroscope Therapeutics and its gene therapy for the sight-robbing disease geographic atrophy (GA) has been acquired by a big pharma company – but likely not the one you would expect. Last year, it also signed a licensing deal with Dyno Therapeutics for its AAV capsid-based gene delivery technology focused on ocular diseases.

Gene Therapy 105

Gene Therapy Gene Licensing Licensing 105

pharmaphorum

MAY 7, 2021

Real-world data is a vital part of rare disease drug development, but to get a true picture of patients’ unmet needs pharma should take a broader view of their lived experiences, says Xperiome’s Jeremy Edwards. He says he would like to see the industry engaging rare disease patients at every stage of drug development.

Development 126

Development Pharma Companies Clinical Trials Clinical Trials 126

Outsourcing Pharma

OCTOBER 6, 2022

The Danish company becomes the latest large pharma company to invest in NLRP3 assets, with these types of treatments holding the potential to treat a variety of diseases linked to inflammation.

Pharma Companies 78

Pharma Companies Clinical Development Development 78

pharmaphorum

JANUARY 24, 2022

Francisco Partners is picking up a range of databases and analytics tools – including Health Insights, MarketScan, Clinical Development, Social Programme Management, Micromedex and other imaging and radiology tools – for an undisclosed sum estimated to be in the region of $1 billion.

Radiology 111

Radiology Marketing Genome Genomics 111

Outsourcing Pharma

OCTOBER 6, 2022

is the first startup to emerge from the alliance of pharma companies and investors that created AION Labs, and will focus on improving the efficacy and safety of drug candidates.

Pharma Companies 72

Pharma Companies Drugs Clinical Development Development 72

pharmaphorum

JULY 1, 2021

The German startup has developed a cuff electrode that allows selective stimulation of fibres in the vagus nerve, which carries an extensive range of signals from the body to the brain and vice versa.

Drug Delivery 94

Drug Delivery Pharma Companies Clinical Development Development 94

Outsourcing Pharma

NOVEMBER 15, 2021

The pharma company has completed enrollment of amyotrophic lateral sclerosis patients in its study investigating drugs like verdiperstat, an oral treatment.

Clinical Trials 69

Clinical Trials Clinical Trials Pharma Companies Trials 69

pharmaphorum

MAY 3, 2022

The new drug – Quviviq (daridorexant) – has been approved by the European Commission for adults who have been suffering insomnia for at least three months and are experiencing “considerable impact” on daytime functioning, according to the Swiss pharma company.

Marketing 97

Marketing Drugs Sales Pharma Companies 97

Pharmaceutical Technology

JUNE 15, 2023

Developing a new drug is a monumental achievement — the reward of years of research and innovation. Successful innovation requires enormous effort from countless project teams that build on the medical, scientific and technological research and development of generations before them.

Pharma R&D 130

Pharma R&D Production Manufacturing Development 130

pharmaphorum

APRIL 22, 2021

Biosensor firm physIQ has licensed its technology to Johnson & Johnson’s Janssen pharma unit in a multi-year deal, to investigate use of wearable sensors in virtual clinical trials. The pharma company will use the technology known as accelerateIQ to collect data across its clinical studies through a variety of wearable biosensors.

Licensing 72

Licensing Licensing Trials Clinical Trials 72

pharmaphorum

MARCH 12, 2021

That was the message from ‘The New Normal: Balancing the rapid evolution of trial design with patient need’ panel at the NIHR’s Clinical Research Network Virtual Event on Delivering Complex and Innovative Design (CID) Studies. Thankfully, many pharma companies seem to be gradually improving on this.

Trials 132

Trials Research Pharma Companies Clinical Trials 132

pharmaphorum

AUGUST 24, 2022

The Food and Drug Administration’s (FDA) draft guidance, Diversity Plans to Improve Enrollment of Participants from Underrepresented Racial and Ethnic Subgroups in Clinical Trials , recommends sponsors develop and submit a race and ethnicity diversity plan early in clinical development. Why, not how.

Clinical Trials 111

Clinical Trials Clinical Trials Trials Development 111

pharmaphorum

NOVEMBER 11, 2022

” Most large pharma companies have also ramped up public commitments to close clinical trial diversity gaps, says the report, including operational measures like inclusive early trial planning, diversity metric tracking, selection of sites, and execution of study participant recruitment programmes.

Clinical Trials 97

Clinical Trials Clinical Trials Trials Pharma Companies 97

pharmaphorum

OCTOBER 15, 2021

Pharma companies are embracing patient centricity in drug development more than ever before. Over the last decade, leaders in the industry have championed patient engagement, putting it at the heart of commercial strategies. I don’t want to be called a patient, and I’m not on a journey.”. “I

Pharma Companies 40

Pharma Companies Clinical Development Medicine Development 40

pharmaphorum

NOVEMBER 3, 2022

We see how digital measures of adherence ensure that sample size calculations hold and drug developers can accurately evaluate the safety and efficacy of new molecules. Pharma companies with more mature digital strategies are able to focus on questions of scale. Moving towards implementation. To us, the benefits are clear.

Clinical Trials 81

Clinical Trials Clinical Trials Trials Medicine 81

pharmaphorum

FEBRUARY 18, 2021

After a year in which the need for digital transformation in pharma reached white heat levels, the sector mustn’t cool off in 2021 and revert to business-as-usual. A return to normal is the longed for goal for many of us, but pharma companies must decide what their future normal should look like.

Medicine 109

Medicine Pharma Companies Development Clinical Trials 109

Outsourcing Pharma

JULY 27, 2020

Elucid Digital Healthâs Pill Connect is designed to enable CROs and pharma companies to monitor patient adherence during a clinical trial.

Pharma Companies 52

Pharma Companies Clinical Trials Clinical Trials Drugs 52

BioPharma Reporter

NOVEMBER 3, 2022

Purdue University and the pharma company will create a scholarship program and renew their strategic research collaboration as part of the agreement.

Manufacturing 52

Manufacturing Pharma Companies Research Clinical Development 52

pharmaphorum

NOVEMBER 12, 2020

The mid-sized pharma group has also signed a collaboration with Florida, US-based Lacerta Therapeutics , adding more AAV capsids – well established as a staple for delivering gene therapy sequences – as well as another gene therapy candidate.

Gene Therapy 52

Gene Therapy Gene Manufacturing Contract Manufacturing 52

Outsourcing Pharma

OCTOBER 24, 2023

Clinical stage pharma company PharmaKure believe their combined drug targeting amyloid deposits associated with Alzheimerâs Disease can bring quality of life to patients.

Pharma Companies 52

Pharma Companies Trials Drugs Clinical Development 52

Outsourcing Pharma

OCTOBER 24, 2023

Clinical stage pharma company PharmaKure believe their combined drug targeting amyloid deposits associated with Alzheimerâs Disease can bring quality of life to patients.

Pharma Companies 52

Pharma Companies Drugs Clinical Development Development 52