Outsourcing Pharma

NOVEMBER 15, 2021

The pharma company has completed enrollment of amyotrophic lateral sclerosis patients in its study investigating drugs like verdiperstat, an oral treatment.

Clinical Trials 69

Clinical Trials Clinical Trials Pharma Companies Trials 69

Outsourcing Pharma

SEPTEMBER 26, 2024

The US big pharma company Pfizer has voluntarily withdrawn the oral sickle cell disease treatment Oxbryta from the market and halted clinical trials of the drug as data indicate a high risk of severe adverse events.

Pharma Companies 76

Pharma Companies Drugs Clinical Trials Clinical Trials 76

XTalks

MAY 11, 2023

Clinical trials are essential for the development of new treatments for rare diseases, but they can be complex and challenging to execute. I’m interested to learn more about the history of rare disease trials as it relates to the patient voice. Wendy: I do think it varies significantly from place to place.

Clinical Trials 97

Clinical Trials Clinical Trials Trials Development 97

pharmaphorum

AUGUST 4, 2020

AstraZeneca has bought an exclusive global licence to develop and market RXC006, a porcupine inhibitor for fibrotic diseases including idiopathic pulmonary fibrosis (IPF). Redx will receive up to $17m in early payments between signing the deal and the successful start of the first clinical trial.

Drugs 109

Drugs Clinical Trials Clinical Trials Trials 109

pharmaphorum

DECEMBER 21, 2021

Novartis has joined the ranks of big pharma companies developing TIGIT-targeted drugs for cancer, and found its candidate in an existing partner, Chinese biotech BeiGene. Pharma companies are looking at whether blocking TIGIT as well as PD-1/PD-L1 can improve the efficacy of cancer immunotherapy.

Drugs 98

Drugs Antibody Pharma Companies Development 98

Outsourcing Pharma

OCTOBER 24, 2023

Clinical stage pharma company PharmaKure believe their combined drug targeting amyloid deposits associated with Alzheimerâs Disease can bring quality of life to patients.

Pharma Companies 52

Pharma Companies Trials Drugs Clinical Development 52

pharmaphorum

DECEMBER 15, 2021

Dialogue requires humility on the drug company’s side—accepting that sometimes we are wrong about matters we think we understand—and trust on the patients’ side that representatives of large, for-profit entities really have come to listen. Previously, Anthony served as the Global Head of Patient Insights, Solutions and Outcomes at Sanofi.

Pharma Companies 145

Pharma Companies Development Medicine Drugs 145

XTalks

MAY 30, 2024

Over the years, his career has evolved from routine case processing at large pharma companies to a more strategic role in smaller settings, where he feels his impact more directly. He notes that the patient voice is critical, and with more involvement, patient advocacy groups will play an important role in clinical development.

Compliance 105

Compliance Clinical Development Pharmacy Development 105

pharmaphorum

MAY 4, 2022

In testing new treatments, what is promising in animal models may not transfer particularly well to humans, which helps to explain why there is a 90% failure rate during clinical development. Once selected, Quris can in-license them, progress them through to phase 1 trials and, those that succeed, can be licensed to pharma companies.

Drugs 143

Drugs Licensing Licensing Pharma Companies 143

pharmaphorum

JANUARY 24, 2022

Francisco Partners is picking up a range of databases and analytics tools – including Health Insights, MarketScan, Clinical Development, Social Programme Management, Micromedex and other imaging and radiology tools – for an undisclosed sum estimated to be in the region of $1 billion.

Radiology 111

Radiology Marketing Genome Genomics 111

The Pharma Data

DECEMBER 21, 2020

The trial will be conducted at 10 sites across Germany and led by principal investigator Prof. The FOCUS trial is Ultimovacs’ fourth Phase II clinical trial with UV1 and comes in addition to the collaboration Phase II trial announced in May 2020. “We Mascha Binder, M.D.,

Vaccination 52

Vaccination Vaccine Trials Clinical Trials 52

pharmaphorum

DECEMBER 22, 2021

Gyroscope Therapeutics and its gene therapy for the sight-robbing disease geographic atrophy (GA) has been acquired by a big pharma company – but likely not the one you would expect.

Gene Therapy 105

Gene Therapy Gene Licensing Licensing 105

Outsourcing Pharma

JULY 27, 2020

Elucid Digital Healthâs Pill Connect is designed to enable CROs and pharma companies to monitor patient adherence during a clinical trial.

Pharma Companies 52

Pharma Companies Clinical Trials Clinical Trials Drugs 52

Pharmaceutical Technology

NOVEMBER 25, 2022

In many cases, pharma companies select a contract development and manufacturing organisation (CDMO) to develop products versus doing the work themselves for reasons related to cost, convenience, and capacity. The differences between adult and paediatric dosage forms are typically significant.

Manufacturing 130

Manufacturing Production Pharma Companies Development 130

pharmaphorum

JULY 1, 2021

Merck and its partners are hoping to have initial data from trials of the bioelectronic device by the end of 2022 , which will then be used to establish a clinical development plan with an eye on getting approvals in major markets like Europe and the US.

Drug Delivery 94

Drug Delivery Pharma Companies Clinical Development Development 94

pharmaphorum

NOVEMBER 3, 2022

As we strive to improve the medical product development process and speed the development of effective new therapies to patients, digital health solutions are becoming increasingly available, affordable, and anticipated in healthcare settings by patients, clinicians, and caregivers alike, driving expectations for trial participants.

Clinical Trials 81

Clinical Trials Clinical Trials Trials Medicine 81

XTalks

SEPTEMBER 5, 2023

Xtalks spoke with Maria Reyes Boceta-Muñoz, Clinical Operations Head of Development R&D at GlaxoSmithKline in Spain, Portugal & Israel, to understand the current vaccine development climate and where the sector is headed.

Vaccination 96

Vaccination Vaccine Development Clinical Trials 96

pharmaphorum

MAY 3, 2022

The new drug – Quviviq (daridorexant) – has been approved by the European Commission for adults who have been suffering insomnia for at least three months and are experiencing “considerable impact” on daytime functioning, according to the Swiss pharma company.

Marketing 97

Marketing Drugs Sales Pharma Companies 97

pharmaphorum

SEPTEMBER 29, 2020

As summarised by The National Institutes of Health, this includes reducing the number of redundant clinical trials, enhancing the statistical strength of studies, reducing overall costs and risks, and improving study participant recruitment, all while triggering creativity and innovation between collaborators.

Research 132

Research Gene Editing Development Gene 132

Pharmaceutical Technology

JUNE 15, 2023

AI in pharma R&D is one of the latest innovations helping teams apply existing knowledge to new problems. Artificial intelligence (AI) has many implications for pharmaceutical companies, including on research, drug discovery and development, manufacturing and trials.

Pharma R&D 130

Pharma R&D Production Manufacturing Development 130

pharmaphorum

MAY 7, 2021

This philosophy was behind Xperiome’s recent decision to split into two different functions – Raremark, a community where patients and carers can share their experiences of living with rare diseases, and Xperiome, which leverages those insights for pharma companies looking to develop drugs for these conditions. About the author.

Development 126

Development Pharma Companies Clinical Trials Clinical Trials 126

pharmaphorum

JUNE 16, 2021

California biotech Ambrx Biopharma is hoping to raise $126 million from a listing on the New York Stock Exchange (NYSE) that will be used in part to fund clinical development of ARX-788, its HER2-targeting antibody drug conjugate (ADC). The company plans to list on the NYSE with the AMAM ticker.

Antibody 59

Antibody Sales Drugs Trials 59

Delveinsight

NOVEMBER 29, 2020

Key players such as Novartis , Annexin Pharmaceuticals , Gene Signal , Ocular Therapeutics , and Asclepix Therapeutics along with other pharma companies are investigating their candidates proactively in a quest to launch their therapies as soon as possible in the Retinal vein occlusion market.

Marketing 52

Marketing Drug Delivery Pharma Companies Clinical Trials 52

pharmaphorum

FEBRUARY 18, 2021

After a year in which the need for digital transformation in pharma reached white heat levels, the sector mustn’t cool off in 2021 and revert to business-as-usual. A return to normal is the longed for goal for many of us, but pharma companies must decide what their future normal should look like.

Medicine 109

Medicine Pharma Companies Development Clinical Trials 109

pharmaphorum

NOVEMBER 23, 2021

GSK gets worldwide rights to the potentially first-in-class drug, with the exception of China, and will be wholly responsible in its markets for clinical development and commercialisation. Preliminary data has shown that the drug can reduce levels of HSD17B13 protein as well as other liver enzymes that are biomarkers for NASH.

Sales 52

Sales Drugs Trials RNA 52

pharmaphorum

APRIL 28, 2022

Although they have, by definition, small addressable markets, the treatments cost just as many resources to develop as therapies for more common diseases – sometimes more, because of the added difficulty of finding sufficiently large patient populations for trials and finding disease experts to run them. So that is the trick.

Pharma Companies 59

Pharma Companies Branding Development Marketing 59

pharmaphorum

JANUARY 29, 2021

Lilly is paying $20 million upfront for exclusive rights to AK1780, a P2X7 receptor antagonist in early-stage clinical development for neuroinflammatory pain conditions, outside Japan and China.

Licensing 52

Licensing Licensing Bioavailability Antibody 52

Delveinsight

MARCH 1, 2021

The US FDA is working with stakeholders, including patients, patient advocates, product developers, and researchers, to fulfill its multiple, complex responsibilities towards improving rare disease clinical development. However, in the end, developing therapies and drugs for rare diseases is a team sport and a team effort.

Marketing 52

Marketing Clinical Trials Clinical Trials Drugs 52

pharmaphorum

MAY 14, 2021

Not only did Ploos van Amstel begin talks before big pharma rivals got wind of the development, his team was able to put forward a potentially broad development plan that could include PsA, AS and HS as well as psoriasis. It’s extremely possible a pharma company may want to partner and it can have many forms.

Drugs 66

Drugs Licensing Licensing Development 66

pharmaphorum

OCTOBER 26, 2022

For example, at the SSIEM Annual Symposium earlier this month, the company shared data on a new candidate for the treatment of Fabry disease, a rare genetic blood disorder. Chiesi’s approach to these trials presents a clear demonstration of Chiesi’s patient-centricity approach in action. Caring for a global community.

Development 96

Development Trials Marketing Life Science 96

Delveinsight

AUGUST 17, 2020

million in 2019 and is anticipated to increase at a CAGR for the study period 2017-2030 owing to dynamic pipeline therapies in the mid-/ late-stage clinical development and rising gastroparesis prevalence. However, double-blind trials have reported results on the contrary with practically no alleviation of symptoms.

Marketing 54

Marketing Trials FDA Approval Clinical Development 54

pharmaphorum

JUNE 8, 2021

Dr Jay Mei from Antengene tells us how the Asia Pacific region is opening up to innovative pharma companies, and gives tips for companies navigating this enormous market. From 2008 to 2017, he served as an executive director of the clinical development department at Celgene (now part of Bristol-Myers Squibb).

Marketing 105

Marketing Drugs Development Regulation 105

pharmaphorum

MAY 21, 2021

It builds on the company’s four partnership projects: two with the generics and biosimilars firm Hikma, one with US biotech Inhibrix and another with an unnamed biosimilars partner. Regulators may not require the large phase 3 trials needed to approve completely new drugs, as safety is proven.

Insulin 52

Insulin Drugs Production Marketing 52

Delveinsight

AUGUST 24, 2020

A few days back, AzurRx demonstrated the caliber of its recombinant lipase enzyme, MS1819 in the treatment of severe exocrine pancreatic insufficiency (EPI) in patients with cystic fibrosis (CF) in the first five patients in a Phase 2 combination therapy trial. Million in 2017. .

Marketing 52

Marketing Production Pharma Companies Containment 52

Pharma Marketing Network

JUNE 8, 2020

As Bob and I were talking about our experiences, almost every strategic kickoff meeting I would go to, the client at the pharma company or whatever would say, you know there’s X amount of people who suffer with this condition but it’s underappreciated, under acknowledged, under diagnosed and under treated. Bob (83Bar): Yes, we do.

Doctors 40

Doctors Doctor Clinical Trials Clinical Trials 40

pharmaphorum

FEBRUARY 11, 2021

Pharma companies face many challenges when involving patients in the design of clinical trials – but doing so can have huge benefits further down the line, improving the sustainability and quality of research.

Clinical Trials 101

Clinical Trials Clinical Trials Trials Clinical Research 101

Roots Analysis

MAY 21, 2024

Due to which, several big pharma companies and other industry stakeholders are actively contributing towards development of protein degradation therapies and technologies, contributing towards growth of targeted protein degradation market.

Protein 40

Protein Marketing Development Antibody 40