The Pharma Data

MARCH 30, 2021

In Europe, KEYTRUDA is approved for the treatment of adult patients with advanced or metastatic urothelial carcinoma (bladder cancer) who are not eligible for cisplatin-containing chemotherapy and whose tumors express PD-L1 with a Combined Positive Score (CPS) ?10. Merck has the industry’s largest immuno-oncology clinical research program.

FDA Approval 52

FDA Approval Containment Trials Genome 52

WCG Clinical

NOVEMBER 17, 2023

Although the NIH Guidelines were originally written with non-clinical laboratory research in mind, they also apply to human gene transfer (HGT) research, wherein rsNA or rsNA-containing products are administered to research participants.

Genome 52

Genome Genomics Gene Editing Genetic Engineering 52

XTalks

OCTOBER 7, 2024

In addition, recent clinical research and new therapeutic approvals bring promising advances in managing rheumatic and musculoskeletal diseases (RMDs). The primary endpoint targets a 50 percent improvement in psoriatic arthritis symptoms (American College of Rheumatology 50 [ACR50]) at Week 16. Top-line results are anticipated in 2026.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Research 52

The Pharma Data

OCTOBER 18, 2020

This study is the first to show that by increasing NAD + , NR helped protect telomeres which are important in addressing life-threatening telomere-related diseases, paving the way for future clinical research.

DNA 52

DNA Scientist Genetic Disease Research 52

pharmaphorum

AUGUST 5, 2021

Protein-protein interactions (PPIs) are becoming increasingly relevant in the pathology of many diseases, including cancer. PPIs are an integral part of the physiology of living organisms, as complexes which control biological pathways mediated by proteins. These regions are critical for optimal interactions between proteins.

Protein 126

Protein Gene Bioassay DNA 126

The Pharma Data

NOVEMBER 16, 2020

I want to thank the NIH, particularly NIAID, for their scientific leadership including through years of foundational research on potential pandemic threats at the Vaccine Research Center that led to the discovery of the best way to make Spike protein antigens that are being used in our vaccine and others’. About mRNA-1273.

Vaccination 52

Vaccination Vaccine Clinical Trials Clinical Trials 52

The Pharma Data

JANUARY 25, 2021

The AD-SAB will work closely with NervGen as the Company plans its upcoming preclinical studies and clinical trials and in the analyses of the results from these studies. NervGen’s platform technology targets protein tyrosine phosphatase sigma (“PTP?”), ”), a neural receptor that impedes nerve repair.

Clinical Development 40

Clinical Development Containment Development Research 40

Advarra

MARCH 10, 2023

SCD’s significant impact on African Americans also means it predominantly impacts a minority community historically underserved by clinical research. Red blood cells contain hemoglobin, a protein that carries oxygen.

Clinical Trials 98

Clinical Trials Clinical Trials Trials Doctors 98

The Pharma Data

JULY 6, 2021

Food and Drug Administration (FDA)-approved test, with disease progression on or after two or more prior lines of therapy including fluoropyrimidine- and platinum-containing chemotherapy and if appropriate, human epidermal growth factor receptor 2 (HER2)/neu-targeted therapy. 1)] as determined by a U.S.

FDA Approval 52

FDA Approval Containment Trials Genome 52

The Pharma Data

JULY 8, 2021

KEYTRUDA has shown meaningful efficacy in patients with locally advanced or recurrent or metastatic cutaneous squamous cell carcinoma that cannot be cured by surgery or radiation,” said Dr. Vicki Goodman, vice president, clinical research, Merck Research Laboratories. 1) as determined by an FDA-approved test.

FDA Approval 52

FDA Approval Containment Trials Genome 52

XTalks

SEPTEMBER 30, 2024

XTALKS CLINICAL EDGE: Issue 3 — Interview with Clene Nanomedicine Xtalks Clinical Edge is a magazine for clinical research professionals and all who want to be informed about the latest trends and happenings in clinical trials. High levels of Nf-L are a sign of active neurodegeneration.

Research 59

Research Clinical Trials Clinical Trials Drugs 59

The Pharma Data

JANUARY 10, 2021

Editas Medicine is preparing to initiate the RUBY clinical trial, a Phase 1/2 trial designed to assess the safety and efficacy of EDIT-301 for the treatment of sickle cell disease. The Company has identified a lead principal investigator and engaged a Clinical Research Organization (CRO).

Medicine 52

Medicine Development Clinical Trials Clinical Trials 52

The Pharma Data

OCTOBER 27, 2020

As a class, DARPin® therapeutics have demonstrated over years of clinical research a number of characteristics that enhance their profile as antiviral therapeutics for a global pandemic. ” Collaboration Terms and Share Subscription. million doses of MP0420, if it is approved in Switzerland. About DARPin® therapeutics.

Development 40

Development Protein Manufacturing Medicine 40

XTalks

AUGUST 18, 2023

Khanani, director of clinical research at Sierra Eye Associates, Reno, Nevada, in Iveric Bio’s news release. RELATED: Apellis’ Syfovre Approved as First Treatment for Geographic Atrophy Despite Uncertain Clinical Benefit What Is Geographic Atrophy? Izervay contains avacincaptad pegol sodium, an effective complement C5 inhibitor.

FDA Approval 52

FDA Approval Drugs Clinical Trials Clinical Trials 52

XTalks

NOVEMBER 7, 2022

“Liquid biopsies have demonstrated promising activity in multiple clinical settings, but the great enthusiasm and expectations around them can be harmful if not adequately managed,” said Dr. El Mustapha Bahassi, PhD, Director, Clinical Laboratory Sciences, at the global clinical research organization (CRO) Medpace.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

The Pharma Data

JANUARY 14, 2021

Associate Professor of Medicine at UCLA, Co-director of the Gastrointestinal Oncology Program and Director of Early Phase Clinical Research at the Jonsson Comprehensive Cancer Center. Five Prime collaborates with leading global pharmaceutical companies and has therapies in pre-clinical and clinical development.

Trials 52

Trials HR Containment Development 52

The Pharma Data

MARCH 23, 2021

Merck has the industry’s largest immuno-oncology clinical research program. The KEYTRUDA clinical program seeks to understand the role of KEYTRUDA across cancers and the factors that may predict a patient’s likelihood of benefitting from treatment with KEYTRUDA, including exploring several different biomarkers.

HR 52

HR FDA Approval Containment Genome 52

The Pharma Data

NOVEMBER 30, 2020

The study also included communities that have historically been under-represented in clinical research and have been disproportionately impacted by COVID-19. These medically high-risk groups represent 42% of the total participants in the Phase 3 COVE study. About mRNA-1273. Department of Defense Contract No. W911QY-20-C-0100.

Vaccination 52

Vaccination Vaccine Medicine Clinical Trials 52

The Pharma Data

AUGUST 31, 2021

The NICE recommendation was based on results from the Novartis ORION clinical research program, including Phase III trials ORION-9, ORION-10 and ORION-11, which involved over 3,600 patients and assessed the safety, efficacy and tolerability of inclisiran in lowering LDL-Cholesterol levels 7,8,9. Disclaimer.

Containment 52

Containment Production RNA Medicine 52

The Pharma Data

JANUARY 24, 2021

It will be run through the NIAID-supported Infectious Diseases Clinical Research Consortium (IDCRC), with support from the Bill & Melinda Gates Foundation. VP-102 is a proprietary drug-device combination that contains a GMP-controlled formulation of cantharidim delivered by way of a single-use applicator.

Trials 52

Trials Allergies In-Vitro Antibody 52

The Pharma Data

DECEMBER 20, 2020

It is an optimized, non-chemically modified mRNA that codes for the prefusion stabilized full-length spike protein of the SARS-CoV-2 virus. eTrueNorth is actively recruiting COVID-19-positive patients about potential participation in the NIH’s ACTIV-2 clinical research trial.

Trials 52

Trials Gene Therapy Vaccination Vaccine 52

The Pharma Data

MAY 13, 2021

Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease. Fructose-containing sugars, blood pressure, and cardiometabolic risk: a critical review. Clinical Research Strategies for Fructose Metabolism. PMID: 25003263.

Insulin 52

Insulin Production Hormones Medicine 52

The Pharma Data

SEPTEMBER 1, 2020

study investigator and Professor of Clinical Neurology, University of California San Francisco (UCSF) Weill Institute for Neurosciences and clinical research director, UCSF MS Center. Inhibition of drug transporter breast cancer resistance protein has no effect on the pharmacokinetics of major active metabolites of ozanimod.

Trials 52

Trials Clinical Trials Clinical Trials Vaccination 52

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. By the end of August, the World Health Organization (WHO) counted 33 vaccine candidates in some stage of clinical trial evaluation. The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein.

Vaccination 92

Vaccination Vaccine Antibody Life Science 92