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US researchers examined geneexpression in more than a million brain cells collected post-mortem from 191 donors. Those with schizophrenia and older adults were found to have a comparitively reduced expression of specific genes in both […]
XTALKS WEBINAR: How to Overcome Trial Planning and Patient Recruitment Challenges Live and On-Demand: Friday, January 24, 2025, at 11am EST (4pm GMT/UK) Register for this free webinar to obtain insights to improve trial planning, stakeholder engagement and patient recruitment outcomes. in mSLEDAI-2K compared to placebo.
The authors of the study say their research is the first to link COVID-19 to molecular signatures of brain aging. “We observed that geneexpression in the brain tissue of patients who died […].
The company is currently testing its lead candidate, EXG-34217 — an autologous cell therapy in Phase I/II trials for treating telomere biology disorders (TBDs), conditions known to cause bone marrow failure with treatments mainly limited to complicated bone marrow transplants. This metaphor captures the essence of their therapeutic approach.
Further evidence of its potential efficacy as a drug candidate was also established based on diminished hypothalamic inflammatory geneexpression. Demonstrating a robust safety profile can be considered a major milestone because previous melanocortin-based drug candidates had significant cardiovascular side-effects in clinicaltrials.
based weight loss intervention in adults with obesity: A randomized clinicaltrial. ClinicalResearch Strategies for Fructose Metabolism. Reduced Reward-driven Eating Accounts for the Impact of a Mindfulness-Based Diet and Exercise Intervention on Weight Loss: Data from the SHINE Randomized Controlled Trial.
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