pharmaphorum

SEPTEMBER 12, 2022

Alongside drugs and therapeutics, data collection and technology enhancements have redefined the traditional healthcare experience, especially within oncology, and genomic profiling has become a significant factor in allowing for personalised care. In other words, every person’s cancer has its own genetic construct. Tailored oncology.

Genome 105

Genome Genomics Clinical Trials Clinical Trials 105

Medical Xpress

JANUARY 5, 2023

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care. This approach contrasts with the typical phenotype-first approach to clinical research, which starts with clinical findings.

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Genome Genomics Genetics Genotype 67

Cloudbyz

JUNE 26, 2023

Generative artificial intelligence (AI) techniques are increasingly being applied in clinical research to enhance various aspects of medical data analysis, diagnosis, treatment planning, and drug discovery. These notes have been used to advance research in NLP and clinical decision support systems.

Clinical Research 97

Clinical Research Research Clinical Trials Clinical Trials 97

Medical Xpress

DECEMBER 20, 2022

Southampton clinical researchers, working as part of a UK team, have shed new light on causes of bronchiectasis, a long-term lung condition currently effecting more than 200,000 people in the UK.

Genome 102

Genome Genomics Clinical Research Research 102

Scienmag

FEBRUARY 19, 2021

Anaylsis shows different genetic risk landscape for IBD In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

Genome 50

Genome Genomics Genetics Clinical Research 50

XTalks

JUNE 12, 2024

It leverages various patient-specific factors, including genetics, age, weight, organ function and even lifestyle, to determine the most appropriate dosage for each individual. Her career spans pediatric clinical pharmacy, clinical research and pharmacogenomics with leadership roles at University of Chicago Medical Center and PipelineRx.

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Life Science Pharmacy Doctors Doctor 97

pharmaphorum

OCTOBER 7, 2021

However, developments in genomic medicine are making huge strides to improve this situation, and these will also be discussed during the webinar. He also serves as haematology consultant to the NICU and genetics service and is co-director of the NIH/Johns Hopkins Pediatric Hematology/Oncology Fellowship Program. About IQVIA.

Genome 98

Genome Genomics Medicine Life Science 98

ACRP blog

JUNE 7, 2023

If you hadn’t already noticed, the clinical research enterprise has well and truly entered the era of “big data,” artificial intelligence (AI), and machine learning. It also includes search and support services that help patients understand, find, and enroll in clinical trials.”

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Big Data Clinical Research Research Clinical Trials 59

pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. The potential to leverage genomic data.

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Development Genome Genomics Drugs 98

Roots Analysis

MARCH 24, 2022

Scientific fields involved in high throughput measurement of biological molecules are referred with the suffix- omics including, transcriptomics, genomics, proteomics and metabolomics. Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. Web: [link].

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Medical Xpress

DECEMBER 29, 2022

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

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RNA Genome Genomics Clinical Research 68

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Partnerships and Establishing Research Cohorts. Genomic biomarker discovery helps drive the development of innovative new personalized therapies.

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Medical Xpress

NOVEMBER 21, 2022

In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS).

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Gene Therapy Gene Genome Genomics 55

The Pharma Data

OCTOBER 27, 2020

.” The single-reaction panel targets five regions of the viral genome and provides excellent accuracy and sensitivity. “Most real time qPCR-based assays target only two or three targets on the viral genome.” “Most real time qPCR-based assays target only two or three targets on the viral genome.”

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Genetic Analysis Genome Genomics Reagent 52

XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. What is it Like to Work as a Clinical Scientist? A clinical scientist is often synonymous with: Clinical Research / Clinical Laboratory Scientist.

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Scientist Life Science Clinical Research Doctors 105

WCG Clinical

NOVEMBER 17, 2023

This change expanded the definition of HGT research to include research using nucleic acids that are able to replicate, be transcribed, translated into protein, and/or integrate into the host genome. Since then, however, certain genetic engineering technologies (e.g.,

Genome 52

Genome Genomics Gene Editing Genetic Engineering 52

XTalks

DECEMBER 1, 2020

Fortunately, technological advances — such as those pioneered by Menarini Silicon Biosystems — have allowed researchers and healthcare practitioners to decipher these issues, drilling down to single-cell genomic levels to uncover variations that may account for reduced drug efficacy or biochemical resistance.

Clinical Trials 96

Clinical Trials Clinical Trials Trials Clinical Research 96

WCG Clinical

AUGUST 27, 2024

The NIH Guidelines also stipulate that at least two members of each IBC come from the surrounding community and be unaffiliated with the institution where the research is occurring apart from their membership on the IBC. Many of those original concerns of the 1970s and 1980s surrounding genetic engineering have lessened over time.

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Genetic Engineering Engineer Compliance Genetics 52

pharmaphorum

MAY 18, 2022

To support the wide range of patients this complex disease impacts, who suffer from a diverse range of symptoms, it is critical that research into this area continues. “At Charl believes we are witnessing the ‘decade of the brain’ with significant leaps in scientific understanding of disease pathways and genetic correlations.

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Gene Therapy Gene Genetics Development 92

XTalks

SEPTEMBER 16, 2024

Lung-MAP is a pioneering clinical trial designed to simultaneously test multiple treatments for non-small cell lung cancer (NSCLC) under a single, comprehensive “umbrella” protocol. Lung-MAP is testing several different treatments that target genetic changes found in NSCLC.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Clinical Research 52

Cloudbyz

JULY 31, 2024

This revolution is enabling the growth of innovative biomarker-based precision medicine and cell and gene therapy, transforming both clinical research and post-market care. For instance, in oncology, patients with specific genetic mutations (e.g.,

Gene Therapy 52

Gene Therapy Gene Medicine In-Vitro 52

Trialfacts

SEPTEMBER 12, 2024

About the Research Center: Boston Children’s Hospital The research enterprise at Boston Children’s Hospital, involving over 3,000 researchers, is the largest in the world at a pediatric center. This includes the pathogenesis of Atopic Dermatitis Location What’s Next?

Research 52

Research Gene Editing Biobanking Bioinformatics 52

Advarra

NOVEMBER 29, 2022

The BGTC will act as a traffic light for these therapies, providing information on basic and clinical research, manufacturing, production, and regulatory requirements. While each ultra-rare genetic disorder may have a very small patient population, when these conditions are grouped together, they make up a significant number.

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Gene Therapy Gene Production Clinical Trials 52

XTalks

FEBRUARY 27, 2024

Rare Disease Day 2024, which falls on February 29 this year, is an opportunity to unite under a common cause: to bring attention to the challenges faced by those living with rare diseases and to push for advancements in research, treatment and policy.

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Research Drugs Gene Therapy Clinical Trials 59

Worldwide Clinical Trials

APRIL 7, 2025

Solid tumors present a significant challenge to clinical research due to their complex and heterogeneous nature. Proactively Address Key Recruitment Challenges in Solid Tumor Clinical Research Solid tumor clinical research is challenging, especially because of tumor heterogeneity.

Medicine 100

Medicine Research Clinical Trials Clinical Trials 100

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. Why should research be any different?

Genetic Disease 97

Genetic Disease Genetics Research Genome 97

pharmaphorum

AUGUST 5, 2021

A recent clinical research paper highlights the importance of targeting of PPIs in stem cells of cancer. A PPI network was constructed from nine colon stem cell markers in order to identify potential genetic targets in patients. This innovative method now brings technology closer to developing genome-wide PPI networks.

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pharmaphorum

SEPTEMBER 16, 2022

Essentially, the collaboration brought together both “the right expertise and the right technology”, opening up myriad possibilities for targeting GPCRs within the human genome. It also bodes well for improving clinical trial success rates. A notable issue with clinical trials is the homogeneity of the patient database.

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Development Research Drugs Clinical Trials 135

XTalks

MARCH 25, 2021

Ayesha obtained an MSc in Cancer & Genetics from McMaster University and a PhD in Medical Biophysics from the University of Toronto. She has presented her research at international conferences and published several peer-reviewed papers.

Life Science 105

Life Science HR Clinical Trials Clinical Trials 105

XTalks

SEPTEMBER 12, 2023

Biomedical Research and Technologies: Get access to the most recent biomedical research news from both industry and academia, including preclinical studies and technological breakthroughs in genomics, single cell analysis, proteomics, metabolomics and much more.

Life Science 105

Life Science Branding Clinical Trials Clinical Trials 105

XTalks

APRIL 24, 2023

Approximately 72 percent of rare diseases are genetic, and around 70 percent of rare genetic diseases emerge in childhood. Watch the free, on-demand webinar and gain valuable insights from this team of clinical research experts. Rare diseases can often be progressive, chronic and fatal.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Dr. Bahassi explained that technological advances in genetic sequencing of cfDNA have enabled liquid biopsies and led to marked increase in the detection of therapeutically-targetable mutations.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

pharmaphorum

DECEMBER 20, 2022

Through the use of genomic, proteomic, epigenetic, immunopeptidomic, and microscopy technologies, scientists are better able to examine cancer cells, molecules, and ecosystems at unprecedented resolution. ICR will use its discovery science to understand the genetic and molecular basis of cancer, and the cancer ecosystem.

Scientist 98

Scientist Research Genetics Drugs 98

The Pharma Data

JANUARY 10, 2021

Nasdaq: EDIT), a leading genome editing company, today announced the U.S. Food and Drug Administration (FDA) has cleared the initiation of the safety phase of the Company’s EDIT-301 clinical trial, and the Company can begin dosing patients. Clinical trial materials are being manufactured by Editas Medicine. CAMBRIDGE, Mass.,

Medicine 52

Medicine Development Clinical Trials Clinical Trials 52

XTalks

JUNE 18, 2024

XTALKS CLINICAL EDGE: Issue 2 — Elixirgen Therapeutics’ Interview Xtalks Clinical Edge is a magazine for clinical research professionals and all who want to be informed about the latest trends and happenings in clinical trials.

Protein 52

Protein RNA Genetics Gene Expression 52

WCG Clinical

OCTOBER 8, 2024

Latin America’s genetic diversity and unique health challenges are driving groundbreaking clinical research, offering new insights into disease prevention, innovative medicine, and treatments. The region’s drive for the development of innovative treatment and prevention strategies contributes to the advancement of global health.

Clinical Research 52

Clinical Research Research Vaccination Vaccine 52

pharmaphorum

DECEMBER 7, 2021

The researchers from the Cleveland Clinic discovered the association between Viagra and a lower risk of Alzheimer’s as part of a wide-ranging study that looked at more than 1,600 FDA-approved medicines to try to find drugs that could be re-purposed as dementia therapies.

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