Pharmaceutical Technology

JUNE 16, 2023

The Abu Dhabi Department of Health (DoH) in the UAE has made a declaration of collaboration with Mass General Brigham’s (MGB) International Center for Genetic Disease (iCGD) to advance life sciences.

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Life Science Genetic Disease Genome Genomics 130

Scienmag

JULY 22, 2021

of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology. . — A new study by Fergus Couch, Ph.D.,

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Genetics Clinical Research Research Medicine 74

Cloudbyz

JUNE 26, 2023

Generative artificial intelligence (AI) techniques are increasingly being applied in clinical research to enhance various aspects of medical data analysis, diagnosis, treatment planning, and drug discovery. This can aid in personalized medicine, disease management, and risk assessment, leading to improved patient care and outcomes.

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Clinical Research Research Clinical Trials Clinical Trials 97

XTalks

SEPTEMBER 9, 2024

Diversity, equity and inclusion (DEI) have become important elements in the landscape of clinical research. Xtalks spoke with Stacy Weil, DHI, Senior Vice President, Business Operations and Patient Centricity, Premier Research, to gain insights into incorporating DEI practices and plans in clinical research.

Clinical Research 101

Clinical Research Research Clinical Trials Clinical Trials 101

XTalks

APRIL 13, 2022

About 80 percent of rare diseases have a genetic basis. Most rare diseases are chronic conditions, and many are clinically progressive and potentially fatal. Aspects of Pediatric Medical Research. Challenges in Pediatric Rare Disease Clinical Trials. Trial Considerations for Pediatric Rare Disease Clinical Research.

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Clinical Trials Clinical Trials Clinical Research Trials 98

XTalks

NOVEMBER 15, 2024

Drug resistance in DEEs often stems from genetic and molecular factors unique to each syndrome, limiting standard treatments’ effectiveness. Bexicaserin’s development has also gained regulatory support in Europe, where the European Medicines Agency’s (EMA) Paediatric Committee endorsed its potential use in children as young as two.

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Trials Clinical Trials Clinical Trials Genetics 97

Scienmag

MAY 26, 2021

Findings published in Science Translational Medicine Credit: Cleveland Clinic May 26, 2021, CLEVELAND: According to new findings published in Science Translational Medicine, Cleveland Clinic researchers have identified a promising drug target for treating and preventing aggressive, drug-resistant prostate cancer.

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Clinical Research Research Drugs Medicine 61

Worldwide Clinical Trials

NOVEMBER 27, 2023

Due to inherited genetic mutations, the red blood cells of patients with severe sickle cell disease become misshaped and jagged, leading to obstructed blood vessels, intense pain, damaged organs, and other serious complications such as stroke.

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Gene Editing Gene Gene Therapy In-Vivo 189

Worldwide Clinical Trials

MARCH 20, 2024

In the increasingly advancing world of medicine, personalized care is a key factor that can progress your drug development efforts. One way to ensure customized disease management is to utilize pharmacogenomics (PGx) in your clinical trial. Reduces Trial Failures Oftentimes, clinical trials may fail due to a lack of efficacy.

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Clinical Trials Clinical Trials Trials Genetics 130

ACRP blog

JUNE 7, 2023

If you hadn’t already noticed, the clinical research enterprise has well and truly entered the era of “big data,” artificial intelligence (AI), and machine learning. Undoubtedly, the expectations for precision medicine are high,” Olsen adds.

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Big Data Clinical Research Research Clinical Trials 59

XTalks

JUNE 12, 2024

It leverages various patient-specific factors, including genetics, age, weight, organ function and even lifestyle, to determine the most appropriate dosage for each individual. Her career spans pediatric clinical pharmacy, clinical research and pharmacogenomics with leadership roles at University of Chicago Medical Center and PipelineRx.

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Life Science Pharmacy Doctors Doctor 97

Worldwide Clinical Trials

JUNE 21, 2024

The 2024 ASCO Annual Meeting from the American Society of Clinical Oncology is a fantastic platform for clinical researchers to discuss the latest advancements and challenges in oncology research.

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Antibody Clinical Trials Clinical Trials In-Vitro 162

ACRP blog

APRIL 24, 2023

Courtney Burnett’s personal story, a brief history, and endless gratitude For patients and physicians alike, clinical research provides hope that ongoing innovation will offer new options to treat and even cure challenging illnesses. points out that modern healthcare and evidence-based medicine would not exist without clinical trials.

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Clinical Trials Clinical Trials Trials Medicine 98

pharmaphorum

NOVEMBER 27, 2022

The Scottish Precision Medicines Industry Group (SPMIG) – set up by AstraZeneca, Lilly, Novartis and Roche – is calling on NHS Scotland to make genomic testing available for every cancer patient in the country, so they can receive drugs based on the molecular profile of their tumours, if available.

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Genome Genomics Genetics Medicine 104

Cloudbyz

JULY 31, 2024

The landscape of modern medicine is rapidly evolving, driven by groundbreaking advancements in diagnostics. This revolution is enabling the growth of innovative biomarker-based precision medicine and cell and gene therapy, transforming both clinical research and post-market care.

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Gene Therapy Gene Medicine In-Vitro 52

Roots Analysis

MARCH 24, 2022

Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. This approach is often employed to determine the effect of genetic modifications or therapeutics in pharmacokinetic studies of drug metabolism. Untargeted Metabolomics. Our Social Media Platform. Web: [link].

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Velocity Clinical Research

AUGUST 8, 2024

Before that, he’d spent 36 years in primary care, treating patients skewed toward the age group most at risk of Alzheimer’s, and it was this experience that, in part, encouraged him to cross over into clinical research. “It If you took a pill today, that was backed by research.” But that requires the tools to build a regime.

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Clinical Trials Clinical Trials Genetics Clinical Research 105

pharmaphorum

APRIL 26, 2022

Diversity is complex and successfully incorporating it into clinical trial designs requires a multilevel and intersectional approach. Potential barriers that exclude communities from clinical research. Read and download the full Achieving diversity, equity and inclusion in clinical trials whitepaper.

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Clinical Trials Clinical Trials Trials Clinical Research 98

pharmaphorum

OCTOBER 7, 2021

However, developments in genomic medicine are making huge strides to improve this situation, and these will also be discussed during the webinar. He also serves as haematology consultant to the NICU and genetics service and is co-director of the NIH/Johns Hopkins Pediatric Hematology/Oncology Fellowship Program. About IQVIA.

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Genome Genomics Medicine Life Science 98

pharmaphorum

SEPTEMBER 12, 2022

Everyone’s genetic makeup differs, and each person’s cancer experience is unique to them – how cancer develops, how fast it spreads, which drugs it responds to, and more. Furthermore, each cancer has various gene changes – also referred to as the genetic makeup of cancer. Tailored oncology. Navigating barriers to access.

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Genome Genomics Clinical Trials Clinical Trials 105

Medical Xpress

FEBRUARY 21, 2025

A clinical research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and international genetic researchers led a global research study using multi-omics analysis and identified a novel gene, DDX39B, for a rare disease.

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Gene Research Genetics Clinical Research 40

XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. What is it Like to Work as a Clinical Scientist? A clinical scientist is often synonymous with: Clinical Research / Clinical Laboratory Scientist.

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Scientist Life Science Clinical Research Doctors 105

Scienmag

FEBRUARY 19, 2021

Anaylsis shows different genetic risk landscape for IBD In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

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XTalks

DECEMBER 1, 2020

Over the past several years, personalized medicine has led the charge in medical innovation, leading drug development efforts as well as furthering the research community’s understanding of human disease states. A Global Lab Service Platform.

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Clinical Trials Clinical Trials Trials Clinical Research 96

Medical Xpress

DECEMBER 29, 2022

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

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RNA Genome Genomics Clinical Research 68

pharmaphorum

SEPTEMBER 28, 2022

NIH’s All of Us is building an extensive, diverse biomedical dataset to learn how biology, lifestyle, and environment affect one’s health, and to accelerate research and improve personalised medicine options. The datasets accelerate research primarily by acting as a resource to researchers, Mendoza says.

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XTalks

MAY 17, 2023

The Foundation for the National Institutes of Health (FNIH) announced this week that the Accelerating Medicines Partnership Bespoke Gene Therapy Consortium (AMP BGTC) has selected eight rare diseases for its clinical trial portfolio. Of the more than 10,000 rare diseases, more than 80 percent are caused by genetic defects.

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Gene Therapy Clinical Trials Clinical Trials Gene 98

XTalks

AUGUST 11, 2021

Xtalks and Genuity Science recently hosted a webinar where lupus experts from around the world gathered to discuss the progress and challenges of their research. Lupus Experts Reflect on their Research. He describes how geneticists have identified at least 100 genetic variants that are enriched in lupus patients.

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Development Drugs Clinical Trials Clinical Trials 105

Medical Xpress

NOVEMBER 21, 2022

In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS).

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Gene Therapy Gene Genome Genomics 55

FDA Law Blog

NOVEMBER 10, 2024

FY2024 Awardees & Observations For the FY2024 Orphan Products Clinical Trials Grants Program, FDA received 51 grant applications and awarded only seven new clinical trials a grant, providing more than $17.2 million to clinical researchers over the next four years to advance the development of medical products for rare diseases.

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Production Clinical Development Development Regulation 69

Cloudbyz

MARCH 5, 2024

In the intricate dance of drug discovery and development, two protagonists emerge as the cornerstones of modern medicine: biologics and small molecules. Monitoring and managing immunogenicity is a complex aspect of clinical trials for biologics.

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Development Drugs Immune Response Manufacturing 97

pharmaphorum

MARCH 31, 2022

UK startup Sano Genetics has raised $11 million in first-round financing to develop its go-between service, which aims to overcome one of the big challenges in clinical research by connecting patients with trial sponsors.

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Trials Genetics DNA Clinical Trials 52

pharmaphorum

APRIL 22, 2021

Cell therapy is a treatment involving the genetic modification and reprogramming of a patient’s immune cells to target their own specific cancer, making it a truly individualised medicine. This thought leadership series has been paid and developed by Kite, a Gilead Company. But we can’t – and don’t – do this alone.

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Research Clinical Trials Clinical Trials Trials 98

pharmaphorum

DECEMBER 21, 2021

Additionally, the work being done within Rare Disease networks, formed of specialty sites, pharma companies, CROs, researchers, and other stakeholders, can all benefit from the value generated by real world genomic data, as outlined by panellist Dr Joanne Hackett, Head of Genomic and Precision medicine at IQVIA.

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Development Genome Genomics Drugs 98

Olympian Clinical Research

NOVEMBER 30, 2023

The exact cause of vitiligo is still under investigation, with factors like genetics , autoimmune responses, and environmental triggers all playing potential roles. The Evolution of Vitiligo Treatments From ancient remedies to modern medicine, the treatment of vitiligo has undergone a remarkable transformation.

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Clinical Research Clinical Trials Clinical Trials Immune Response 52

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. This includes precision medicine strategies which can be effectively guided through high-level translational research led by clinical data.

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Cloudbyz

NOVEMBER 30, 2021

Although you may hear some argue that with regulations catching up, and a few COVID-19 setbacks and challenges, change isn’t happening fast enough, these 6 trends we’ve identified in clinical research will prove to you that change in the clinical trial industry shows no sign of slowing down anytime soon. Personalized Medicine.

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Clinical Trials Clinical Trials Trials Clinical Research 52