This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Yet researchers have suspected there could be more to the story. Now two new studies raise the possibility of complex interactions between hormones and […]
The constant ebb and flow of hormones that guide the menstrual cycle don’t just affect reproductive anatomy. Led by neuroscientists Elizabeth Rizor and Viktoriya Babenko of the University of California Santa Barbara, a team of researchers tracked 30 women […]
New research by our team has identified sensitivity to a hormone made in abundance by the developing pregnancy, GDF15, […] Sickness in pregnancy, or hyperemesis gravidarum, is common and is thought to affect seven out of ten women at some time in their pregnancy.
Millions around the world must inject the crucial hormone underneath their skin several times a day to keep their glucose levels in balance. The most effective way for people with diabetes to deliver insulin is also incredibly intrusive.
The pill, called Opill – the brand name for the tablet formulation of norgestrel – is an oral contraceptive containing only progestin hormone, which helps prevent pregnancy […]
Pfizer has been going strong on the approval front, having secured its fifth US Food and Drug Administration (FDA) approval in the past five weeks, with the most recent being for the company’s once-weekly human growth hormone analog Ngenla (somatrogon-ghla).
Unlike drugs that alter metabolism or appetite by interacting with hormones, the pill functions entirely mechanically. Traditional methods like diet and exercise often fail to provide long-term success, and newer pharmacological options like hormone-based GLP-1 agonists, while effective, can be expensive and carry side effects.
Semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro) are the most well known in the class of drugs that mimic hormones to reduce feelings of hunger. Drugs like Ozempic are very effective at helping most people who take them lose weight. But does weight come back when you stop using […]
If you’re someone who has to deal with a period regularly, you’re probably all too familiar with just how much your energy levels can change throughout your cycle thanks to hormonal fluctuations.
Eneboparatide (AZP-3601), an investigational parathyroid hormone 1 receptor (PTH1R) agonist, met its primary endpoint in the CALYPSO Phase III trial, offering new data for adults with chronic hypoparathyroidism. AstraZeneca received eneboparatide during its $1.05 Without proper PTH function, patients may face kidney and bone complications.
Latin America’s genetic diversity and unique health challenges are driving groundbreaking clinicalresearch, offering new insights into disease prevention, innovative medicine, and treatments. The barbasco root is a plant used in Mexican traditional medicine that has been used to develop synthetic hormones. [1]
The US Food and Drug Administration (FDA) has approved Itovebi (inavolisib) for the treatment of adults with hormone receptor-positive (HR-positive), human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with a PIK3CA mutation. Why Target PIK3CA Mutations?
You can help with STI research while also getting treatment for your own infections. DM ClinicalResearch is currently running studies on a new product that may protect against STIs. Migraine Research. If you suffer from migraines, then a clinical trial might help you find relief. Click here to learn more.
Sweden-based biotech Camurus shared positive Phase III trial data for CAM2029, one of its lead candidates, in patients with the rare hormonal disorder acromegaly. Octreotide is a synthetic analog of somatostatin, a hormone in the body that inhibits the release of several other hormones, including growth hormone (GH), glucagon and insulin.
Standard treatment strategies include combinations of antibiotics, hormonal therapies and biologic agents most notably adalimumab (Humira), the only FDA-approved biologic for moderate to severe cases while surgery remains an option for advanced disease.
The San Antonio Breast Cancer Symposium (SABCS) has highlighted some of the most promising clinicalresearch being undertaken by drugmakers in the category, with AstraZeneca leading the charge with a trio of major trial readouts.
Petrelintide, administered once a week under the skin, targets obesity through its action as an amylin analog, a hormone co-secreted with insulin from the pancreas. By mimicking this hormone, petrelintide may offer an alternative or complement to incretin-based therapies, known for their role in weight management.
Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Douglas collaborates with scientific researchers and external medical experts to advance clinicalresearch.
Douglas provides products in various therapeutic areas which include psoriasis, eczema, dermatitis, chicken pox, constipation, laxative, neonatal, hormone regulation, dermatology, cardiovascular and measles, among others. Douglas collaborates with scientific researchers and external medical experts to advance clinicalresearch.
Pediatric growth hormone deficiency (PGHD) is one such condition, affecting a child’s growth and development. This rare endocrine disorder, characterized by inadequate secretion of growth hormone from the pituitary gland, has profound impacts on physical and sometimes cognitive development.
Not surprisingly, hormone shifts are to blame for this head pain. This is because of estrogen, a key hormone for women. Falling estrogen levels are typically the cause of migraines and other hormonal headaches. Not all women will get hormonal headaches. Here’s How to Find Relief appeared first on DM ClinicalResearch.
Merck has said it will abandon the KEYNOTE-991 study of PD-1 inhibitor Keytruda (pembrolizumab) in patients with metastatic hormone-sensitive prostate cancer (mHSPC) after it showed no benefit on either overall survival (OS) or radiographic progression-free survival (rPFS) when the data was analysed midway though.
What do you know about your hormones? However, hormones are about much more than making babies. Your body releases dozens of hormones every single day. The endocrine system is a network of glands that help to manage these hormones. The post Endocrine System Questions for Patients appeared first on DM ClinicalResearch.
How Hormones Affect Migraine Headaches. A woman’s hormones will become unpredictable leading up to menopause, which can cause unpredictable headaches. Some women feel better after using hormone replacement therapy. Consider a Clinical Trial. Migraine Research in Houston. But what causes these headaches?
This type of depression may occur after childbirth and is thought to be caused by a sudden hormone change. PMDD is thought to be caused by a combination of hormonal and brain chemistry changes. Look for Clinical Studies on Depression at Olympian ClinicalResearch. Symptoms of PMDD.
With ongoing research and clinical trials , institutions like Olympian ClinicalResearch are at the forefront of finding innovative treatment options. Hormonal Changes: Hormonal fluctuations, especially during puberty, can influence the severity and onset of psoriasis. What is Pediatric Plaque Psoriasis?
From reproductive health concerns to hormonal fluctuations and societal pressures, women encounter a. Women’s health is a multifaceted journey that requires proactive care and attention to various physical, emotional, and social factors. Read more The post Empowering Women’s Health appeared first on MyLocalStudy.com.
For example, pediatric growth hormone deficiency (PGHD) affects approximately one in 3,500 to one in 10,000 children. Existing therapeutic options for PGHD consist of injectable formulations of recombinant human growth hormone (rhGH), administered subcutaneously either on a daily or weekly basis.
Knowing this, it’s no surprise that the way IBD affects women’s menstrual cycle hasn’t been thoroughly researched, even though a significant percentage of women with IBD report menstrual irregularities as well as intensifying of GI symptoms before and during their period. Other hormones, prostaglandins, may play an important role as well.
While the exact cause is unknown, factors like genetics, inflammation, and hormones play a role. Here are some common triggers of HS: Hormonal Changes: Many individuals with HS report flare-ups during periods of hormonal change, such as menstruation, pregnancy, or menopause.
“Triple-negative carcinoma grows and spreads faster than other sorts of carcinoma and consequently features a worse prognosis,” said Dr. Vicki Goodman, vice chairman , clinicalresearch, Merck Research Laboratories. Merck has the industry’s largest immuno-oncology clinicalresearch program.
Once a diagnosis is confirmed, your provider may order other clinical and microscopy exams, including: Complete blood cell count (CBC). Thyroid hormone panel. Explore New Treatments With Olympian ClinicalResearch . appeared first on Olympian ClinicalResearch. Comprehensive metabolic panel (CMP).
When we are under stress, our bodies release cortisol, a hormone that can weaken the skin’s natural barrier and make it more susceptible to irritation and inflammation. That’s why we are dedicated to conducting clinicalresearch trials to help advance the science of eczema treatment and management.
Unlike the reigning blockbuster GLP-1 drugs on the market namely Novo Nordisks Wegovy (semaglutide) and Eli Lillys Zepbound (tirzepatide), the latter of which is a dual agonist of the GLP-1 and GIP receptors Amgens MariTide is an antibody-peptide conjugate that combines a GLP-1 receptor agonist (consisting of two peptides that mimic the GLP-1 hormone) (..)
. “Trodelvy is the cornerstone of our solid tumour portfolio,” commented Bill Grossman, Gilead’s head of oncology clinicalresearch. “We look forward to rapidly advancing our development program in Asia and to realizing the clinical potential of Trodelvy across diverse tumour types.”
Advise patients of these risks and the need for effective non-hormonal contraception. WELIREG can render some hormonal contraceptives ineffective. Advise patients of these risks and the need for effective non-hormonal contraception as WELIREG can render some hormonal contraceptives ineffective.
Participants will undergo study visits, where they will have their rate of stomach emptying, blood sugar and gut hormone levels, and blood pressure measured for approximately 5-6 hours, on day 1 (before treatment), 12 weeks after treatment, and 1 and 4 weeks (after stopping the treatment). Contents About the Study Why Participate?
Unlike the reigning blockbuster GLP-1 drugs on the market — namely Novo Nordisk’s Wegovy (semaglutide) and Eli Lilly’s Zepbound (tirzepatide), the latter of which is a dual agonist of the GLP-1 and GIP receptors — Amgen’s MariTide is an antibody-peptide conjugate that combines a GLP-1 receptor agonist (consisting of two peptides that mimic the GLP-1 (..)
3, 2020 /PRNewswire/ — The National Comprehensive Cancer Network ® ( NCCN ® ) Oncology Research Program ( ORP ) today announced five projects selected to receive funding for clinical and preclinical evaluation of abemaciclib. .
PLYMOUTH MEETING, Pa. ,
While clinicalresearchers occasionally need to identify and validate a new surrogate endpoint for a given trial, choosing endpoints that have been previously used as the basis of NDAs and BLAs can clear the path to eventual approval. The tumor secretes adrenocorticotropic hormone (ACTH), which stimulates cortisol production.
Published in the November issue of JAMA Oncology , this is the first study to support clinical utility of CTC count in a randomized clinical trial. mL received hormone therapy. The results supported the reliability and clinical utility of using the CTC count to guide front line therapy choice.
CNP is a hormone produced by the body that plays an important role in the bone growth of children. Researchers at Parexel want to understand how a new study drug, TransCon CNP behaves in the body. About the Research Center: Parexel. Some children with achondroplasia may also have neurological or developmental challenges.
This research could lead to a more convenient and accessible treatment option. Trial results were presented at the ADA sessions and published in The Lancet.
Leo Chen Research centre focusing on improvement of existing treatments for depression, schizophrenia, complex trauma disorder, PMDD and other conditions. Our key areas of focus are currently hormones, cognition, TMS. Locations What’s Next?
We organize all of the trending information in your field so you don't have to. Join 21,000+ users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content