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In a new commentary, members of the NIH Pragmatic Trials Collaboratory’s Ethics and Regulatory Core explore the potential of pragmatic trials to improve demographic representativeness and health equity in clinical research. Representativeness in Pragmatic ClinicalTrials,” was published online ahead of print in JAMA.
An elderly woman in Russia’s Far East was revealed on Wednesday to have lived for 80 years with an inch-long needle in her brain, after doctors made the unexpected discovery during a CT scan. Doctors believe the woman was the victim of a failed infanticide carried out by her parents, and said they would not […]
QUICK READ: Patients are returning to their doctor’s office, and it’s not uncommon for appointments, or routine visits, to be scheduled weeks or months in advance. When I sent an email to my doctor’s office, I was shocked when she said the earliest appointment she had for physicals was in September.
At a medical conference, the companies detailed clinicaltrial results that could help support approval of their drug, lecanemab. However, some doctors aren’t yet convinced the medicine’s risks are worth its potential benefits.
Congratulations to the study team on reaching this important milestone for all NIH Collaboratory Trials! IMPACt-LBP is evaluating the effect of first-contact patient referral to physical therapists and doctors of chiropractic for low back pain. Read the full study design paper.
Teleconsultation is seen as a viable alternative with low doctor-to-population ratio and shortage of specialists doctors. In fact, teleconsultation is seen to bridge this gap by allowing patients in remote areas to receive earlier diagnosis and treatment with low cost and faster follow-up check-ups.
India’s smart doctor promoters are seeking help of professional healthcare management companies to introduce best healthcare management practices in their establishments, said Raj Sehgal associate director, TR Lifesciences. This is because these clinics encounter challenges even as there are growth prospects.
This was a multisite, practice-based, comparative effectiveness randomized clinicaltrial conducted at six public hospitals and three academic medical centers in New York City. Front-line doctors were instrumental in helping the research teams onboard the sites and think through recruitment.
Drugs like Ozempic are very effective at helping most people who take them lose weight. Semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro) are the most well known in the class of drugs that mimic hormones to reduce feelings of hunger. But does weight come back when you stop using […]
In an invited commentary published this month in Circulation: Cardiovascular Quality and Outcomes , authors from the NIH Pragmatic Trials Collaboratory’s Ethics and Regulatory Core describe the recurring and emerging ethical issues in pragmatic clinicaltrials. Learn more about the Ethics and Regulatory Core.
(Science Photo Library/Getty Images) Has your doctor asked you to stick out your tongue and say “aaah”? The doctor will look for any changes in the tongue’s surface or how it moves. While the GP assesses your throat, they’re also checking out your tongue, which can reveal a lot about your health.
Over the last two years, Sahyadri Hospitals in Pune has observed a troubling trend of increase in cases of pulmonary embolism (PE) associated with long-haul international travel.
On the other hand, we did make a thought elder, who worked on clinicaltrials of a cancer drug, to take questions from other physicians about those clinicaltrials. Finally, after the storm of the pandemic, many doctors re suddenly overwhelmed with patients. What you have to say and how you say are more important.
The Siddha medical practitioners working under the Kerala ISM department and assigned with various Central and state government projects have joined hands to form an organisation of government Siddha medical officers on the lines of the Kerala Government Ayurveda Medical Officers Association.
On closer inspection using a CT scan, the doctors discovered his severe headaches were the result of several cysts throughout his brain. A 52-year-old Florida man presented to hospital with complaints that his usual migraines had worsened over the past four months.
Positive results from a late-stage clinicaltrial of the drug, called lecanemab, were a surprising success for a field used to setbacks. But doctors and researchers point out that the reported benefit appears relatively modest.
Today, unsweetened cranberry juice is often recommended by doctors as a treatment for urinary tract infections (UTIs), and yet given a lack of solid scientific evidence, some researchers have argued that “any continued promotion” of […]
Bertagnolli emphasized this, stating the EHR needed to become a learning environment, facilitating both the collection and dissemination of knowledge even for busy doctors. “We We need to make it possible for busy doctors and clinics to be in a learning environment,” she said.
Not just because of the physical pains it causes, but because it can also be such a pain to go to the doctor, provide a urine sample, and wait for your results. If you’ve ever had a urinary tract infection (UTI) before, you know what a pain it can be. Skip advert UTIs are extremely […].
As hematologists (blood doctors), we are often asked for advice when people are worried they might bruise too easily. But what if we find ourselves bruising without any noticeable cause? What might be behind it? Should we worry? Around 18 percent of adults report easy bruising. Here […]
In 2011, I participated in a Type 1 diabetes clinicaltrial and have continued exploring study opportunities ever since. I always kept up with my doctor’s appointments and insulin. Then in 2019, my doctor suggested a continuous glucose monitor (CGM) for better control. Still, I refused to let diabetes define me.
This is why doctors recommend regular screening for several common cancer types, using a variety of methods. Detecting cancer early before it spreads throughout the body can be lifesaving. Colonoscopies, for example, screen for colon cancer, while mammograms screen for breast cancer.
A prohibition against puberty blocking hormones and gender-affirming surgeries for minors in Florida was tightened further after a board overseeing doctors eliminated an exception for clinicaltrials Friday at the request of Florida Gov. Ron DeSantis' administration.
In this Q&A, Andrea discusses their experience, especially as it relates to the two clinicaltrials Tom participated in. We wanted to participate in a clinicaltrial. But our original doctor doesn’t work with clinicaltrials—it’s just not his thing. How was your husband diagnosed with ALS?
Rishi Chakraborty Co-led by investigators at Duke University and Dartmouth University, IMPACt-LBP is a cluster randomized trial of a multidisciplinary collaborative team approach for low back pain versus usual care.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
For individuals living with a condition like melanoma, volunteering to participate in a clinicaltrial can be a rewarding experience. Individuals with Jamie’s specific diagnosis are given a 14% 5-year survival rate — but through participating in an immunotherapy clinicaltrial, Jamie is living without evidence of the disease.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
Over the last year, we’ve noticed that “connectivity” doesn’t always equate to “connected” – and that’s just as true in the realm of clinicaltrials as it is in our personal lives. Amanda Barrell reports from a panel at the Patients as Partners Europe conference on remote clinicaltrials. Building engagement.
The Kolkata headquartered All India Chemists and Distributors Federation (AICDF), a breakaway group of the AIOCD and a body of pharmaceutical distributors and retailers across the country, has informed the government of West Bengal that a period of use or an expiry date, on the lines of the use of therapeutics, is necessary for doctors’ […]
The vacancies of teaching faculties in the two government ayurveda medical colleges in the state of Telangana still remain vacant despite pressures from association of ayurveda doctors and educational experts on the government wanting appointment of regular faculties.
By Cathy Purvis, MBA; Site Activation Manager, Oncology and Rare Disease, Worldwide ClinicalTrials. I quickly became intrigued by the complex nature of the study/site processes and did whatever I could to meet and beat targets, despite the additional oversight that often accompanies oncology trials.
In our ClinicalTrials blog series, we’ve covered topics such as how to find the right clinicaltrial , how to find and pay for clinicaltrials , and even if you have rights in a clinicaltrial. Today, we want to de-bunk some common clinicaltrial myths. You are not alone!
Following the increased use of telemedicine during the Covid-19 pandemic, the potential of digital technologies in communication, data collection, and analysis has become increasingly realised by patients, healthcare systems, and clinicaltrial sponsors.
They found widespread combination prescribing of drugs classified as Schedule II controlled substances with a high potential for psychological or physical dependence and with limited combined clinicaltrial testing.
In-home nurse visits, using familiar mobile devices to upload health data, and telemedicine calls with a doctor are the elements of decentralized clinicaltrials with the biggest positive impact on participation in future studies, according to a survey.
There are many aspects of oncology drug development that are driven by the unique nature of the treatments being developed and the needs of the patients, their caregivers and the doctors that treat them. Evolution in Oncology ClinicalTrial Design Recent discussions at ESMO highlight a shift in how clinicaltrials are designed and conducted.
The FDA approval is based on findings from the multicentre Phase II CENTAUR clinicaltrial that enrolled 137 ALS patients. For the first three weeks, the recommended dose is one packet a day. Following this time period, the dosage is raised to one packet twice daily.
SUMMARY: Doctors said they were dissatisfied were marketing emails (46%), telephone sales calls with sales reps (42%), and both webinars and websites (each at 39%) from pharma companies, according to Indegene. Also, one message to ALL doctors sold not make sense. They especially like data about clinicaltrial updates.
doctors surveyed in the same time period, 77% said their trust in the CDC has decreased and 48% said their trust in the FDA has decreased. According to Medscape, “doctors and nurses reported relatively lower trust in the CDC than WebMD readers. Out of nearly 450 U.S.
Her organization, along with BlackDoctors.org and Black Doctors Against Covid, also presented multiple webinars that reached tens of thousands online. “We I think that that has resonated with people because at Morehouse School of Medicine we did not have any challenges with enrolling persons in the clinicaltrials.”.
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