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In a new commentary, members of the NIH Pragmatic Trials Collaboratory’s Ethics and Regulatory Core explore the potential of pragmatic trials to improve demographic representativeness and health equity in clinicalresearch. appeared first on Rethinking ClinicalTrials. ” Read the full article.
The research team looked at the comparative effectiveness of HBPTM alone versus HBPTM plus telephone-based NCM when administered to Black and Hispanic stroke survivors with uncontrolled hypertension. The research team found that both groups experienced significant SBP reduction at both the six-month and 12-month mark.
An elderly woman in Russia’s Far East was revealed on Wednesday to have lived for 80 years with an inch-long needle in her brain, after doctors made the unexpected discovery during a CT scan. Doctors believe the woman was the victim of a failed infanticide carried out by her parents, and said they would not […]
In an invited commentary published this month in Circulation: Cardiovascular Quality and Outcomes , authors from the NIH Pragmatic Trials Collaboratory’s Ethics and Regulatory Core describe the recurring and emerging ethical issues in pragmatic clinicaltrials. Learn more about the Ethics and Regulatory Core.
recent retrospective study, however, suggests the thymus gland is not nearly as expendable as experts once thought US researchers found that those who get their thymus removed face an increased risk of death from any cause […]
Teleconsultation is seen as a viable alternative with low doctor-to-population ratio and shortage of specialists doctors. In fact, teleconsultation is seen to bridge this gap by allowing patients in remote areas to receive earlier diagnosis and treatment with low cost and faster follow-up check-ups.
Speaking at the NIH Pragmatic Trials Collaboratory’s 2024 Annual Steering Committee Meeting in May, Commissioner of Food and Drugs Robert Califf and NIH Director Monica Bertagnolli discussed the intersection of pragmatic research and national health priorities. View the full materials from the 2024 Annual Steering Committee Meeting.
India’s smart doctor promoters are seeking help of professional healthcare management companies to introduce best healthcare management practices in their establishments, said Raj Sehgal associate director, TR Lifesciences. This is because these clinics encounter challenges even as there are growth prospects.
In this Q&A, Andrea discusses their experience, especially as it relates to the two clinicaltrials Tom participated in. We wanted to participate in a clinicaltrial. But our original doctor doesn’t work with clinicaltrials—it’s just not his thing. And I started researchingtrials.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
Today, unsweetened cranberry juice is often recommended by doctors as a treatment for urinary tract infections (UTIs), and yet given a lack of solid scientific evidence, some researchers have argued that “any continued promotion” of […]
Drugs like Ozempic are very effective at helping most people who take them lose weight. Semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro) are the most well known in the class of drugs that mimic hormones to reduce feelings of hunger. But does weight come back when you stop using […]
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinicaltrial design.
For individuals living with a condition like melanoma, volunteering to participate in a clinicaltrial can be a rewarding experience. Individuals with Jamie’s specific diagnosis are given a 14% 5-year survival rate — but through participating in an immunotherapy clinicaltrial, Jamie is living without evidence of the disease.
In 2011, I participated in a Type 1 diabetes clinicaltrial and have continued exploring study opportunities ever since. I always kept up with my doctor’s appointments and insulin. Then in 2019, my doctor suggested a continuous glucose monitor (CGM) for better control. Still, I refused to let diabetes define me.
Positive results from a late-stage clinicaltrial of the drug, called lecanemab, were a surprising success for a field used to setbacks. But doctors and researchers point out that the reported benefit appears relatively modest.
Over the last year, we’ve noticed that “connectivity” doesn’t always equate to “connected” – and that’s just as true in the realm of clinicaltrials as it is in our personal lives. Amanda Barrell reports from a panel at the Patients as Partners Europe conference on remote clinicaltrials. Patients as Partners.
In her own words, a daughter shares how a career in cancer research helped support her mother’s courageous battle with late-stage ovarian cancer. By Cathy Purvis, MBA; Site Activation Manager, Oncology and Rare Disease, Worldwide ClinicalTrials. I landed in oncology thanks to the luck of the draw.
Over the last two years, Sahyadri Hospitals in Pune has observed a troubling trend of increase in cases of pulmonary embolism (PE) associated with long-haul international travel.
Following the increased use of telemedicine during the Covid-19 pandemic, the potential of digital technologies in communication, data collection, and analysis has become increasingly realised by patients, healthcare systems, and clinicaltrial sponsors.
As many as 20% to 50% of clinicaltrials do not accrue participants at the site level, leading to wasted time and financial resources. This waste can be minimized by early selection of trials most likely to succeed. Clinicalresearch is a business that should focus on viable studies.
According to research from HealthLink Dimensions, more than a third of physicians reported using social networks to communicate with their professional peers, and 59% said they see the value in social media and plan to use it as a resource in the future. When using the Internet to reach doctors, numbers don’t matter.
The Siddha medical practitioners working under the Kerala ISM department and assigned with various Central and state government projects have joined hands to form an organisation of government Siddha medical officers on the lines of the Kerala Government Ayurveda Medical Officers Association.
Not just because of the physical pains it causes, but because it can also be such a pain to go to the doctor, provide a urine sample, and wait for your results. If you’ve ever had a urinary tract infection (UTI) before, you know what a pain it can be. Skip advert UTIs are extremely […].
As hematologists (blood doctors), we are often asked for advice when people are worried they might bruise too easily. But what if we find ourselves bruising without any noticeable cause? What might be behind it? Should we worry? Around 18 percent of adults report easy bruising. Here […]
Monitoring patient safety during a clinicaltrial is one of the founding principles to be followed throughout the drug development life cycle. It can be defined as a collaborative relationship between sponsors, sites, researchers, and everyone involved in the clinicaltrial phases.
The partnership between Abbott and non-profit Women as One will train female and underrepresented physicians to help improve diversity in clinicaltrials. In a study that analyzed the demographics of clinicaltrial participants of the 102 new drugs approved between 2013 to 2015 by the FDA’s CDER, only 40.4
Born and trained in Egypt, he moved to the UK several years ago after working as a general practitioner there and deciding he loved the country and the clinicaltrial opportunities it offered. To join a clinicaltrial at Velocity, visit velocityclinicaltrials.com.
Her organization, along with BlackDoctors.org and Black Doctors Against Covid, also presented multiple webinars that reached tens of thousands online. “We I think that that has resonated with people because at Morehouse School of Medicine we did not have any challenges with enrolling persons in the clinicaltrials.”.
The clinicalresearch industry has long struggled with participant diversity. One study found that only 5% of Black or Asian United Kingdom residents had ever participated in a clinicaltrial. A study of FDA-approved vaccine trials from 2011-2020 showed that 78% of participants were white, even though only 60% of the U.S.
Josh Sackman, president and co-founder of AppliedVR, and Web Sun, president and co-founder of Komodo Health, relay how their newly formed collaboration reshapes the clinicaltrial process by using data, helping to cut costs and allowing for evaluation of broader patient populations. .
Barry Mangum talks the importance of pediatric research, its evolution over the years, and the obstacles and opportunities that the industry faces as it moves forward. How long have you been in pediatric clinicalresearch, and how did you enter the field? So I’ve been working in that space about 43 years.
Patty Spears, the Chair of the Patient Advocate Committee at the Alliance for ClinicalTrials in Oncology, shared insights about research advocacy for oncology trials, decentralized trials from the patient perspective and more. Once it is approved the clinicaltrial protocol is developed.
Behind every new treatment is the incredible team of doctors, researchers, patients, and clinicaltrial specialists who worked on the research that made it possible.
It may not be appropriate to use the word ‘failure’ when summarising the utility of clinicaltrials in the search for a curative or preventative treatment for disease. There are many reasons as to why so few eligible patients are being recruited into clinicaltrials even though infection numbers are high.
The vacancies of teaching faculties in the two government ayurveda medical colleges in the state of Telangana still remain vacant despite pressures from association of ayurveda doctors and educational experts on the government wanting appointment of regular faculties.
The Kolkata headquartered All India Chemists and Distributors Federation (AICDF), a breakaway group of the AIOCD and a body of pharmaceutical distributors and retailers across the country, has informed the government of West Bengal that a period of use or an expiry date, on the lines of the use of therapeutics, is necessary for doctors’ […]
Clinicalresearch is part of a growing industry that provides individuals with rewarding career options and a ladder to climb. Working in the clinicaltrials industry allows clinicalresearchers to work with patients and bring new drugs to market. Wondering which clinicalresearch job is right for you?
As part of our patient advocacy efforts, at FindMeCure we are dedicated to creating a bridge between patients and the world of clinicalresearch. This includes spreading clinicaltrial awareness, connecting patients to the trials they are interested in but also speaking up about the issues in the clinicalresearch industry. .
They look to their doctors to inform them of clinicaltrials and treatment options by way of medication or surgical intervention, but they are also interested in learning about nontraditional modalities to achieve relief. If you’re interested in learning more about pain therapeutics research, check out our pain expertise.
Besides her complicated duties as a doctor in neurology at the time, she came to realize that esophageal precancerous lesions were wearing on her body, leading to even greater stressful thoughts about how the health crisis would affect her career and what others would think of her, and eventually to burnout. “I
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