XTalks

MARCH 19, 2025

This week, were celebrating a significant milestone: the release of our 200th episode of the Xtalks Life Science Podcast ! We’re excited to continue our journey by bringing you more in-depth conversations with industry leaders, highlighting the innovations and trends that shape the future of life sciences.

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Pharmaceutical Technology

JUNE 2, 2023

Anavex Life Sciences has secured new US intellectual property compositions patent for its ANAVEX 2-73 (blarcamesine). Anavex’s orally available drug candidate restores cellular homeostasis by targeting sigma-1 and M1 muscarinic receptors.

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Pharmaceutical Technology

DECEMBER 14, 2022

GSK has entered a strategic partnership with Wave Life Sciences to progress the discovery and development of oligonucleotide therapies for new genetic targets. On completion of the first-in-patient clinical trial by Wave, GSK will be in charge of the development and marketing works.

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XTalks

MARCH 14, 2025

Novo Nordisks investigational obesity combination drug, CagriSema (a fixed dose combination of cagrilintide 2.4 mg), underperformed in its latest clinical trial, leading to a dip in the companys share price. In response to the trial outcomes, Novos shares declined by approximately 8% this week. mg and semaglutide 2.4

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Velocity Clinical Research

MARCH 23, 2025

Clinical trials have been steadily leaving the UK for years. of patients recruited to global trials were from the UK. Thats not to say we dont still have some clout (the UK ranks fourth globally for Phase II trials ), but the trending outflow needs to be addressed. In 2021, just 2.2% Whats Causing the Outflow?

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XTalks

FEBRUARY 14, 2023

The life science industry is constantly evolving, making it difficult to stay ahead of the curve. There’s no doubt that pharmaceutical and biotechnology organizations are utilizing innovative technology solutions across all sectors of drug development, research and development, supply chain, manufacturing and more.

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Camargo

NOVEMBER 22, 2021

This year, Camargo is highlighting one of our own, Manager of Life Science Solutions Andrea Miller, who cared for her husband Tom throughout his battle with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease. We wanted to participate in a clinical trial. And I started researching trials.

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XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables.

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XTalks

SEPTEMBER 12, 2023

Life science podcasts have emerged as an invaluable tool for building connections with audiences in the digital era. Furthermore, we’ll explore the unique advertising opportunities that this platform offers, positioning brands at the forefront of the life science industry. The result?

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XTalks

DECEMBER 4, 2024

In this episode, Ayesha spoke with John Yu, MD, CEO of Kairos Pharma , a company advancing therapies to overcome challenges in cancer drug resistance and immune suppression. Kairos is developing therapeutics that reverse cancer drug resistance in cancers such as prostate and lung cancer. Dr. Yu has also led numerous clinical trials.

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Cloudbyz

MARCH 17, 2024

In the dynamic world of life sciences, where innovation is paramount, the integration of cutting-edge technologies is crucial for accelerating clinical operations and driving breakthroughs in healthcare. Salesforce’s recent announcement of its Life Sciences Cloud marks a significant stride towards this goal.

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Pharmaceutical Technology

APRIL 14, 2023

The first-in-class, clinical-stage antibody-drug conjugate (ADC) targeting Claudin 6 (CLDN 6), TORL-1-23 is being developed to treat patients across several cancer types. The lead drug programmes of the company target CLDN 6 and Claudin 18.2 CLDN 18.2). It intends to advance one or two new compounds each year.

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XTalks

DECEMBER 9, 2024

The US Food and Drug Administration (FDA) has released a new draft guidance titled Expedited Program for Serious Conditions Accelerated Approval of Drugs and Biologics Guidance for Industry refining the accelerated approval pathway for drugs and biologics targeting serious or life-threatening conditions.

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XTalks

JUNE 14, 2023

The FNIH recently announced that the AMP Bespoke Gene Therapy Consortium has selected eight rare diseases for its clinical trial portfolio. Xtalks spoke with Dr. Silverthorm about the consortium’s new rare disease clinical trial portfolio. Subscribe to the Xtalks Life Science Podcast to never miss a new episode.

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XTalks

JANUARY 17, 2024

Oncology is recognized as having the largest drug pipeline of any therapeutic area. Given this hotbed of activity, innovation in the space to drive faster decisions and more efficient trials is intense. It’s very positive and it’s going to help move forward the pathway for new drugs.”

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XTalks

AUGUST 23, 2023

BriaCell is developing cell therapies for the treatment of advanced breast cancer and has promising compounds, including Bria-IMT, that are currently being evaluated in clinical trials. Subscribe to the Xtalks Life Science Podcast to never miss a new episode.

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XTalks

JANUARY 8, 2024

Getting a drug to market used to be a relatively simple and straightforward affair. Whether it’s for a treatment for a chronic ambulatory condition, precision medicine or cell and gene therapy, there is a massive uptick in clinical trial complexity. That’s just not the case anymore.

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XTalks

NOVEMBER 12, 2024

World Pneumonia Day 2024 provides an opportunity to examine the latest advances in pneumonia treatment and prevention — and the role that healthcare and life sciences industries play in reducing its global impact. These innovations can help prevent viral pneumonia complications in high-risk groups.

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pharmaphorum

JANUARY 6, 2023

From enabling patient choice during clinical trials to strengthening vital partnerships across the quality ecosystem, connected data will become the lifeblood that enables life sciences teams to collaborate efficiently and effectively in 2023. Data will unlock clinical and economic value in Europe’s challenging landscape.

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XTalks

NOVEMBER 28, 2024

Axsome Therapeutics has released findings from its ENCORE Phase III trial, demonstrating that their investigational drug AXS-12 (reboxetine) significantly reduces cataplexy attacks, improves excessive daytime sleepiness and enhances overall functioning in individuals with narcolepsy. weekly cataplexy attacks compared to 10.29

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XTalks

AUGUST 22, 2023

Recruiting participants is perhaps the most challenging aspect of any clinical trial, regardless of the therapeutic area. Yet this one piece is also the most vital, with a trial’s ability to enroll and retain participants being a key predictor of a study’s future success. What is Clinical Trials For All?

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XTalks

MAY 19, 2023

Clinical trials play a vital role in advancing patient treatment and medical care. This article delves into ten trends and statistics in the world of clinical trials for 2023. Increasing Number of Registered Clinical Trials As of May 17, 2023, there are 452,604 registered clinical trials globally on ClinicalTrials.gov.

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Velocity Clinical Research

OCTOBER 21, 2024

For a clinical trials organization to achieve this level of scale is notable. The clinical trials sector in the US is typically made up of small independent businesses that collectively play an important role in trialing new protocols and aiding drug development. Velocity is among the few exceptions.

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XTalks

MAY 17, 2023

The Foundation for the National Institutes of Health (FNIH) announced this week that the Accelerating Medicines Partnership Bespoke Gene Therapy Consortium (AMP BGTC) has selected eight rare diseases for its clinical trial portfolio.

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XTalks

MAY 24, 2023

Leading health solutions company CVS Health recently disclosed that its clinical trial business will shut down just two years after its initiation in May 2021. The company will gradually wind down its CVS Health Clinical Trial Services unit with full exit by December 31, 2024.

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XTalks

NOVEMBER 14, 2024

PTC Therapeutics has gained US Food and Drug Administration (FDA) approval for its new gene therapy, Kebilidi (eladocagene exuparvovec), for treating aromatic L-amino acid decarboxylase (AADC) deficiency. Kebilidi has a known safety profile from clinical trials. for this purpose.

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Pharmaceutical Technology

APRIL 10, 2023

The HALOS platform is built using an invention from the research team led by Professor Chris Scott, who is the scientific co-founder and chief scientific officer of Aviceda and interim dean of research, faculty of medicine, health, and life sciences, at Queen’s.

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XTalks

MAY 9, 2023

Clinical trial manager jobs are vital for the development and execution of clinical trials, which are essential for developing new treatments for diseases. In this article, we discuss the job duties, education and experience requirements, outlook and salary expectations for clinical trial managers.

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pharmaphorum

OCTOBER 28, 2022

The sooner a human-centred perspective is applied to the development of either a drug or device product, the more likely the product will be adopted and used because it’s been designed around what the end consumer wants and needs. Could this candidate demonstrate clinical efficacy?

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Cloudbyz

MARCH 1, 2023

Clinical trials are a critical component of drug development in the life sciences industry. Conducting clinical trials requires significant investments of time and resources, including the management of budgets and payments.

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XTalks

MAY 16, 2023

Clinical trials for pulmonary fibrosis are being conducted to evaluate the effectiveness of novel therapies and interventions, providing hope for improved outcomes in the future. They aim to improve patient outcomes, slow disease progression and enhance quality of life.

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XTalks

MAY 4, 2023

As of now, the US Food and Drug Administration (FDA) has not approved any drugs for the treatment of celiac disease. However, there are ongoing clinical trials for celiac disease to investigate potential new treatments. How does Beyond Celiac spread awareness about research and clinical trials for celiac disease?

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XTalks

JANUARY 6, 2025

The US Food and Drug Administration (FDA) has approved Alyftrek (vanzacaftor/tezacaftor/deutivacaftor), a next-in-class triple combination cystic fibrosis transmembrane conductance regulator (CFTR) modulator, to treat cystic fibrosis (CF) in patients aged six years and older with at least one F508del mutation or another responsive CFTR mutation.

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Pharmaceutical Technology

NOVEMBER 3, 2022

Emalex Biosciences has raised Series D funds worth $250m led by Bain Capital Life Sciences to progress the development of an investigational new drug for Tourette syndrome. Headache, somnolence, fatigue, insomnia and restlessness were found to be the most common adverse events linked to ecopipam in the trial.

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XTalks

JULY 29, 2024

Orphan drug development poses many challenges that are unique to rare diseases, including recruitment in small patient populations, variable progression with heterogenous clinical manifestations and limited understanding of disease progression and natural history. Read on to learn key lessons in rare disease drug development.

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XTalks

DECEMBER 3, 2024

This technology, already approved by the US Food and Drug Administration (FDA) for glioblastoma and mesothelioma , and most recently for metastatic non-small cell lung cancer (NSCLC), harnesses electric fields to disrupt cancer cell division.

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Pharmaceutical Technology

MAY 16, 2023

Courtney Silverthorn PhD, the associate vice president of translational sciences at the FNIH, said that the BGTC plans to “bring some more standardisation and clarity to the pathway of how you get an AAV gene therapy into a first-in-human clinical trial [for rare diseases].”

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