pharmaphorum

JANUARY 18, 2023

Pharmaceutical companies and biotechs are also adapting their approaches, launching patient finding and engagement programmes that can start years before clinical trials begin and allow them to run ‘recontact by genotype’ studies that the Resilience Project would have liked to do. Giving participants something in return.

Genetic Disease 97

Genetic Disease Genetics Research Genome 97

The Pharma Data

SEPTEMBER 2, 2020

The decision allows use of the therapy in the EU in children as young as six years of age and weighing at least 17kg, regardless of HCV genotype or liver disease severity. Source link.

Genotype 52

Genotype Clinical Trials Clinical Trials Trials 52

XTalks

DECEMBER 12, 2023

The world of neuroscience trials is rapidly evolving, presenting new challenges and opportunities for researchers and clinicians. The worldwide market for neurology clinical trials stood at a valuation of $5.24 There is currently a heightened emphasis on imaging and liquid biomarkers in neuroscience clinical trials.

Trials 111

Trials Clinical Trials Clinical Trials Genetics 111

pharmaphorum

JANUARY 29, 2019

What are the implications from these changes for clinical trials? How the shift towards cancer as a phenotype/genotype is being applied in clinical trials and how they are run •What are co-clinical trials and why could they hold the key to answering unmet need in cancer treatment and beyond into broader drug development?

Genomics 52

Genomics Genome Medicine Clinical Trials 52

pharmaphorum

JANUARY 21, 2022

The findings have been submitted to the Genotype-to-Phenotype National Virology Consortium (G2P-UK), the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) and the Joint Committee on Vaccination and Immunisation (JCVI). Overall, antibody levels were nearly 2.5

Antibody 115

Antibody Vaccine Vaccination Genotype 115

Pharmaceutical Technology

DECEMBER 15, 2022

Since the drug treated CFD population is very small, drug developers are not heavily invested in the space and clinical trials frequently struggle with recruitment, especially in areas with low diagnosed prevalence. CFD is an extremely rare disease in which many patients are often asymptomatic and do not require treatment.

Marketing 130

Marketing Production Genotype Development 130

Pharmaceutical Technology

JUNE 6, 2023

According to Globaldata, it is involved in 5 clinical trials, which are ongoing. Pharma Mar offers in vitro diagnostic products used for detection of virus and bacteria in respiratory infections and human papilloma virus genotypes, among others. Buy the model here.

Hormones 100

Hormones In-Vitro Genotype Bacteria 100

XTalks

APRIL 24, 2023

Melanie Blank, clinical team leader for General Medicine Branch 1 at the US Food and Drug Administration’s (FDA) Division of Clinical Evaluation and Pharmacology/Toxicology (DCEPT), the agency is seeing one or two new applications coming in every week for new gene therapies for different diseases. Reference: Chung DC, et al.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

Scienmag

MAY 16, 2021

The fully human monoclonal antibody produced sustained reductions in triglyceride levels of up to 82 percent, depending on the patient’s genotype, while also lowering the […].

Antibody 45

Antibody Genotype Drugs Clinical Trials 45

Delveinsight

DECEMBER 13, 2020

Even though clinical trial results were promising, adverse events and serious complications were observed. Hepatitis C treatment options, without a doubt, have improved significantly, including pan-genotypic medications that are used to treat all genotypes and subtypes. and GT2 and GT3 with ribavirin. in January 2019.

Genotype 52

Genotype FDA Approval DNA Drugs 52

Bioengineer

JANUARY 16, 2024

Importantly, a triple mutant scenario with EGFR L858R/T790M/C797S or EGFRexon19del/T790M/C797S genotype may occur in patients with T790-positive NSCLC receiving osimertinib in second or later lines. Real-world cohorts report a prevalence of C797 mutations between 11% and 29%.

Genome 119

Genome Genomics Protein In-Vitro 119

XTalks

APRIL 15, 2021

Late-stage clinical trial failures are largely to blame for the lack of effective treatment options for patients with HFpEF, and poor five-year survival rates make this an area of great unmet need. A lack of efficacy is the greatest reason for clinical trial failures, especially in Phase II and Phase III,” says Dr. Tyl.

Development 98

Development Drugs Genome Genomics 98

XTalks

SEPTEMBER 15, 2020

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. So, this really validates what we already knew and now we have prospective results supporting that [from this trial].”.

Vaccine 103

Vaccine Vaccination Insulin Trials 103

XTalks

SEPTEMBER 28, 2020

The test is based on the detection of actionable genes – genes with known driver mutations that can be targeted by an approved therapy (or investigational therapies in clinical trials). The panel of genes in the test only include known NSCLC-associated genes, making the test specific to the disease.

Gene 105

Gene DNA Life Science Genotype 105

The Pharma Data

NOVEMBER 2, 2020

(NASDAQ:ADIL; ADILW) , a clinical-stage biopharmaceutical company focused on the development of treatments for addictions, today provided an update on its landmark ONWARD Phase 3 pivotal trial. 40% of expected Trial patient screenings have been completed and the Trial is more than 25% enrolled relative to planned enrollment.

Trials 52

Trials Genotype Marketing Production 52

XTalks

JANUARY 21, 2025

In a clinical trial, participants demonstrated a 98% success rate after six months post implantation, with arteries widened successfully and no stent fractures observed. Delivered through a minimally invasive catheter system, the stent is positioned using X-ray imaging, then expanded via an inflatable balloon.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

XTalks

FEBRUARY 4, 2021

Through these collaborations, cohort research dataset sharing programs allow for whole-genome sequence and genotype data to be made available for independent research. Now, if all you’ve already got is a bioresource of 20,000 people that have already been genotyped, you can choose those from that sample and focus your effort.”.

Research 98

Research Biobanking Drugs Genomics 98

XTalks

MARCH 3, 2021

The efficacy of Nulibry in the treatment of MoCD Type A was demonstrated in data from three different clinical trials that was compared to data from a natural history study. In the analysis involving 31 patients, 13 were treated with Nulibry and compared to 18 genotype-matched untreated patients from the history control group.

FDA Approval 64

FDA Approval Genotype Clinical Trials Clinical Trials 64

The Pharma Data

NOVEMBER 10, 2020

Although a few are out there, phosphorylated tau (P-tau) may enable even earlier and more accurate detection, according to Eli Lilly-associated researchers speaking at the Clinical Trials on Alzheimer’s Disease (CTAD) virtual conference in early November. ADNI trial. The protocol was identical to the U.S.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Antibody 52

The Pharma Data

SEPTEMBER 2, 2021

Durvalumab ± Tremelimumab + Platinum-Etoposide in 1L ES-SCLC: Exploratory Analysis of HLA Genotype and Survival in CASPIAN. Posters: P47 – Novel Therapeutics and Targeted Therapies – Clinical Trial in Progress. Posters: P47 – Novel Therapeutics and Targeted Therapies – Clinical Trial in Progress. Lead author.

Trials 52

Trials Medicine Antibody Clinical Trials 52

Delveinsight

AUGUST 25, 2021

Apart from these, Xarelto (for PAD) and Darzalex (for Amyloidosis and Refractory Multiple Myeloma) are in Phase III of clinical trials, while Tremfya (for Crohn’s Disease), Seltorexant (for insomnia), and Ciltacabtagene Autoleucei (BCMA CAR-T) (for multiple myeloma) are in Phase II of development. Imbruvica contributed USD 5.3

Vaccination 98

Vaccination Vaccine Drugs Sales 98

The Pharma Data

APRIL 14, 2021

A global, randomized Phase 3 confirmatory clinical trial TROPiCS-04 (NCT04527991) is underway and is also intended to support global registrations. More information on TROPiCS-04 is available at [link]. About Trodelvy.

Genotype 52

Genotype Containment FDA Approval Genotoxicity 52

XTalks

MARCH 1, 2024

Related: Abbott’s HPV Test Gets FDA Approval for High-Risk HPV Detection and Cervical Cancer Screening Next-Generation Sequencing Next-generation sequencing (NGS) technologies are being considered for HPV detection and genotyping.

Vaccine 52

Vaccine Vaccination Life Science FDA Approval 52

The Pharma Data

NOVEMBER 24, 2020

The safety and efficacy of Oxlumo are also being evaluated in the ongoing ILLUMINATE-C Phase 3 clinical trial in patients of all ages with advanced PH1, including patients on dialysis.

FDA Approval 52

FDA Approval Production RNA Medicine 52

XTalks

MARCH 26, 2025

Attendees will learn how clinical trial assays and genotyping kits can enhance research and clinical insight. Kezar noted the decrease was partially offset by the increased clinical trial costs of PALIZADE and PORTOLA. Zetomipzomib is a first-in-class selective immunoproteasome inhibitor. million and $94.2

Trials 66

Trials Life Science Clinical Trials Clinical Trials 66