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Cardiac Biomarkers in Cardiovascular Clinical Trials: Caveats and Considerations

XTalks

Cardiac biomarkers can not only serve important roles in the diagnosis, management and prognosis of cardiac diseases, but they can also be significant tools in evaluating treatments in cardiovascular (CV) clinical trials. In CV clinical trials, cardiac biomarkers are most commonly included in efficacy and safety endpoints.

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Thyroid Awareness Month 2024: Increasing Awareness and Exploring New Treatments for Thyroid Diseases

XTalks

The thyroid plays a critical role in the body by producing hormones that regulate metabolism, heart rate and body temperature among others. Types of Thyroid Conditions There are several different thyroid conditions, with each affecting thyroid hormone production or the gland’s structure, leading to a range of health issues.

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Efruxifermin Combined with GLP-1RA Shows Clinical Efficacy in MASH, Study Reveals

XTalks

Efruxifermin is a novel Fc-FGF21 fusion protein designed to emulate the activity of native FGF21, an endogenous hormone that regulates metabolism and alleviates cellular stress. Numerous compounds are currently under clinical investigation for MASH.

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GLP-1 Agonists for Diabetes: Mounjaro Versus Ozempic

XTalks

GLP-1 receptor agonists, or incretin (metabolic hormones) mimetics, are analogs of the GLP-1 peptide hormone that binds to the GLP-1 receptor to regulate blood sugar levels by boosting insulin secretion. Accordingly, the diabetes drug market is expected to balloon from $29.81 billion in 2021 to $61.6 billion by 2030.

Insulin 98
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World Glaucoma Week 2024: New Advances in Glaucoma Care

XTalks

Related: Transforming Eye Care: Innovating New Glaucoma and Dry Eye Disease Treatments — Featuring Pierre Simon, VP Marketing, Sight Sciences – Xtalks Life Science Podcast Ep. Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects.

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COVID-19 and Melatonin: Researchers Use AI To Study New Treatment Option

XTalks

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. Melatonin, which regulates the body’s circadian rhythm and sleep-wake cycle, is also available in pill form for use as a sleep aid.

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Tafinlar and Mekinist Combination Approved by FDA for Solid Tumors with BRAF V600E Mutation

XTalks

The BRAF gene regulates cell growth, proliferation and apoptosis. Both Tafinlar and Mekinist target the RAS/RAF/MEK/ERK pathway , which regulates cell growth and survival; however, each affects different kinases. Tafinlar and Mekinist Combination Clinical Trial Results.