AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 23, 2024

Semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro) are the most well known in the class of drugs that mimic hormones to reduce feelings of hunger. Drugs like Ozempic are very effective at helping most people who take them lose weight. But does weight come back when you stop using […]

Doctors 189

Doctors Doctor Hormones Drugs 189

XTalks

OCTOBER 23, 2024

Unlike drugs that alter metabolism or appetite by interacting with hormones, the pill functions entirely mechanically. Traditional methods like diet and exercise often fail to provide long-term success, and newer pharmacological options like hormone-based GLP-1 agonists, while effective, can be expensive and carry side effects.

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Production Hormones Drugs Trials 104

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 14, 2022

If you’re someone who has to deal with a period regularly, you’re probably all too familiar with just how much your energy levels can change throughout your cycle thanks to hormonal fluctuations.

Hormones 189

Hormones Clinical Trials Clinical Trials Clinical Research 189

Pharmaceutical Technology

JUNE 1, 2023

A prior orchiectomy or receipt of gonadotropin-releasing hormone (GnRH) analogs was also necessary. According to figures from GlobalData’s clinical trials database, research into mCRPC treatments has been on the rise over the past 10 years. Trials peaked at 115 in 2018 before declining to 91 last year.

FDA Approval 244

FDA Approval Hormones Trials Clinical Trials 244

Pharmaceutical Technology

JANUARY 22, 2023

The mutation leads to disordered thyroid hormone transport, which causes patients to experience intellectual and motor disabilities. Egetis is banking on tiratricol, an oral small molecule that restores dysfunctional thyroid hormone signalling, to be the first drug approved for this condition. In clinical trials, the drug showed a 3.8-point

Drugs 317

Drugs Gene Hormones Clinical Trials 317

Medical Xpress

APRIL 28, 2023

The patient-reported outcomes (PROs) of the phase 3 NRG Oncology clinical trial RTOG 0815 comparing dose-escalated radiotherapy (RT) alone to dose-escalated RT combined with short-term (6 months) androgen deprivation therapy (STAD) indicate that the addition of STAD did not significantly impact urinary or bowel quality of life but did significantly (..)

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Clinical Trials Clinical Trials Trials Hormones 74

Medical Xpress

JANUARY 10, 2025

Prostate cancer that has become resistant to hormone therapy could be treated using a new drug that is currently in clinical trials for ovarian and bile duct cancer, according to research published in the journal Clinical Cancer Research.

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Clinical Trials Clinical Trials Trials Hormones 45

XTalks

JANUARY 30, 2025

Novartis has spent three decades advancing breast cancer treatments, focusing on hormone receptor-positive (HR+), HER2-negative breast cancer, the most common subtype. Last year, the FDA approved Kisqali (ribociclib) to reduce the risk of recurrence in HR+/HER2- early breast cancer. Novartis dedicated approximately $0.47

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HR Hormones FDA Approval Clinical Trials 64

Advarra

JUNE 30, 2023

The Centers for Medicare & Medicaid Services (CMS) released a letter outlining routine costs in clinical trials for patients eligible for Medicaid in April 2022. However, a year has passed with no further updates on this letter or Medicaid beneficiaries enrolling in clinical trials.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Hormones 52

XTalks

MARCH 18, 2025

Incytes recent announcement on the topline results from two Phase III clinical trials of povorcitinib in patients with hidradenitis suppurativa has stirred both hope and caution in the market. Janus kinase one (JAK1) plays a central role in the signaling pathways of several inflammatory cytokines.

Trials 59

Trials Clinical Trials Clinical Trials Hormones 59

XTalks

MARCH 19, 2025

Eneboparatide (AZP-3601), an investigational parathyroid hormone 1 receptor (PTH1R) agonist, met its primary endpoint in the CALYPSO Phase III trial, offering new data for adults with chronic hypoparathyroidism. AstraZeneca received eneboparatide during its $1.05

Trials 59

Trials Hormones Engineer Licensing 59

Pharmaceutical Technology

NOVEMBER 30, 2022

However, there has recently been a boom in interest and research in anti-obesity therapeutics. We’re using a combination of gut hormones to mimic the effectiveness of bariatric surgery. Mounjaro is a combination of the two gut hormones GLP-1 and GIP. million in Q3. weight loss in obese or overweight individuals.

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Drugs Manufacturing Hormones Clinical Trials 264

Worldwide Clinical Trials

JULY 8, 2024

Hormonal Status : A body’s hormones, such as levels of reproductive hormones and thyroid function, can impact tissue responses to radiation therapy. The FDA ensures that radiopharmaceuticals meet stringent criteria for safety, efficacy, and quality before they can be approved for clinical use.

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Hormones Regulation Clinical Trials Clinical Trials 130

XTalks

NOVEMBER 29, 2023

David Cameron, Chair of the Breast International Group (BIG) , we delve into the landscape of breast cancer research today, clinical trials and the incorporation of the patient voice in breast cancer research. For example, the field of molecular research is buzzing with cutting-edge technologies and their applications.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Research 52

Pharmaceutical Technology

NOVEMBER 30, 2022

However, there has recently been a boom in interest and research in anti-obesity therapeutics. We’re using a combination of gut hormones to mimic the effectiveness of bariatric surgery. Mounjaro is a combination of the two gut hormones GLP-1 and GIP. million in Q3. weight loss in obese or overweight individuals.

Drugs 246

Drugs Manufacturing Hormones Clinical Trials 246

XTalks

DECEMBER 13, 2024

Petrelintide, administered once a week under the skin, targets obesity through its action as an amylin analog, a hormone co-secreted with insulin from the pancreas. By mimicking this hormone, petrelintide may offer an alternative or complement to incretin-based therapies, known for their role in weight management.

Drugs 102

Drugs Hormones Trials Clinical Trials 102

XTalks

MAY 17, 2023

Research has indicated that vasomotor symptoms commonly occur during the late perimenopause and early postmenopausal years. While the exact physiology of vasomotor symptoms is not fully understood, it is believed that the significant fluctuations in reproductive hormones play a role in triggering these symptoms. How Does Veozah Work?

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Hormones FDA Approval Drugs Clinical Trials 95

XTalks

JULY 17, 2024

Sweden-based biotech Camurus shared positive Phase III trial data for CAM2029, one of its lead candidates, in patients with the rare hormonal disorder acromegaly. Due to its ability to mimic somatostatin, octreotide is used to treat various conditions associated with excessive hormone production.

Trials 59

Trials Hormones Clinical Trials Clinical Trials 59

Scienmag

SEPTEMBER 29, 2020

20-year research breakthrough offers new hope for high risk patients with HR+ breast cancer A new treatment for breast cancer patients with hormone receptor (HR+) early stage disease who are at a high risk of recurrence has been shown to reduce the risk by 25%, according to a study led by The Royal Marsden NHS […].

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HR Hormones Research Clinical Trials 61

XTalks

JANUARY 9, 2024

The thyroid plays a critical role in the body by producing hormones that regulate metabolism, heart rate and body temperature among others. Types of Thyroid Conditions There are several different thyroid conditions, with each affecting thyroid hormone production or the gland’s structure, leading to a range of health issues.

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Hormones Antibody Trials Production 105

Pharmaceutical Technology

JUNE 5, 2023

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Rezvilutamide is indicated for the treatment of metastatic hormone sensitive prostate cancer. Rezvilutamide overview Rezvilutamide is an antineoplastic agent.

Medicine 100

Medicine Hormones Production Clinical Trials 100

Pharmaceutical Technology

JUNE 5, 2023

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Rezvilutamide is indicated for the treatment of metastatic hormone sensitive prostate cancer. Rezvilutamide overview Rezvilutamide is an antineoplastic agent.

Medicine 100

Medicine Hormones Production Clinical Trials 100

Pharmaceutical Technology

FEBRUARY 24, 2023

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Douglas collaborates with scientific researchers and external medical experts to advance clinical research. The company also offers contract manufacturing and laboratory services.

Contract Manufacturing 100

Contract Manufacturing Dermatology Hormones Production 100

Pharmaceutical Technology

FEBRUARY 24, 2023

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Douglas collaborates with scientific researchers and external medical experts to advance clinical research. The company also offers contract manufacturing and laboratory services.

Contract Manufacturing 100

Contract Manufacturing Dermatology Hormones Production 100

pharmaphorum

AUGUST 11, 2020

A phase 3 trial is expected to begin in 2021 and the company says that the compound could generate peak sales of more than a billion euros globally. Astellas in August last year announced it is beginning pivotal phase 3 clinical trials for fezolinetant, which could be considered a competitor although it only works against the NK3 receptor.

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Drugs Hormones Marketing Trials 98

XTalks

MARCH 7, 2024

Other issues include medical systems that can often be dismissive of women’s health concerns or experiences, and historically less research on women’s health, which together, can lead to late diagnoses or misdiagnoses. Experts discuss the therapeutic landscape, treatment gaps, regulatory considerations and clinical trial strategies.

Genetics 115

Genetics Hormones Genome Genomics 115

XTalks

JANUARY 23, 2024

Rare diseases, often overlooked in the broader medical research field, affect a small percentage of the population yet carry a significant burden for those diagnosed and their families. Pediatric growth hormone deficiency (PGHD) is one such condition, affecting a child’s growth and development.

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Development Hormones Drugs Trials 72

Pharmaceutical Technology

FEBRUARY 23, 2023

Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. The company operates research and development, clinical operation centers in China, and the US. Adlai Nortye is headquartered in Hangzhou, Zhejiang, China.

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Hormones Development Drugs Clinical Trials 130

XTalks

DECEMBER 5, 2024

Amgen announced positive results from a Phase II clinical trial evaluating its investigational obesity drug MariTide (maridebart cafraglutide, formerly AMG 133) for the treatment of obesity and overweight in both diabetic and non-diabetic patients. percent in the 68-week STEP-1 clinical trial.

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Trials Drugs Clinical Trials Clinical Trials 104

Find Me Cure

NOVEMBER 7, 2019

From the way they metabolize drugs to diseases and conditions that mostly affect women (like migraines) and so remain under-researched, there is a medical bias that unfairly affects half the population. However, more in-depth research is needed to understand the link between IBD and menstrual irregularities. .

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Research Hormones Doctor Doctors 52

DM Clinical Research

APRIL 15, 2021

Participating in a clinical trial might be a great option for you. During a clinical trial, you will receive expert medical care free of charge, including doctor’s visits, medications, and follow-up appointments. STI Clinical Trials. Migraine Research. Not sure if our trials are right for you?

Clinical Research 40

Clinical Research Research Clinical Trials Clinical Trials 40

pharmaphorum

DECEMBER 8, 2020

Amanda Barrell speaks to Alfred Samuels on his experience of prostate cancer and diversifying clinical trials to include the Black, Asian and minority ethnic (BAME) community. Alfred is an ambassador for Cancer Research UK, which funded the STAMPEDE trial, and works with groups including The Urology Foundation and Orchid.

Clinical Trials 98

Clinical Trials Clinical Trials Trials Hormones 98

pharmaphorum

MAY 16, 2022

GLP-1 and GIP are hormones involved in blood sugar control and Mounjaro, a first-in-class medicine that activates both GLP-1 and GIP receptors, demonstrated improved blood sugar control. The findings were made via Lilly’s SURPASS phase 3 global clinical development programme, which comprised studies ranging from 40 to 52 weeks.

FDA Approval 115

FDA Approval Insulin Drugs Hormones 115

Scienmag

MAY 21, 2021

HIV prevention services will be combined with access to gender-affirming hormonal therapy and peer health navigation to try to reduce the disproportionate percentage of transgender women who are HIV positive in an innovative study led by researchers at The University of Texas Health Science Center at Houston (UTHeath).

Hormones 49

Hormones Research Clinical Trials Clinical Trials 49

XTalks

DECEMBER 5, 2024

Amgen announced positive results from a Phase II clinical trial evaluating its investigational obesity drug MariTide (maridebart cafraglutide, formerly AMG 133) for the treatment of obesity and overweight in both diabetic and non-diabetic patients. percent in the 68-week STEP-1 clinical trial.

Trials 96

Trials Drugs Clinical Trials Clinical Trials 96

XTalks

MAY 23, 2024

For example, pediatric growth hormone deficiency (PGHD) affects approximately one in 3,500 to one in 10,000 children. Existing therapeutic options for PGHD consist of injectable formulations of recombinant human growth hormone (rhGH), administered subcutaneously either on a daily or weekly basis.

Clinical Trials 52

Clinical Trials Clinical Trials Hormones Trials 52

Trialfacts

MARCH 1, 2023

Researchers and Actinogen Medical are currently exploring a new potential treatment, Xanamem®, for those with depressive symptoms who are also experiencing cognitive symptoms. If you have been diagnosed with depression and would like to contribute to the development of a potential new treatment, then consider joining this research study!

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Research Clinical Trials Clinical Trials Containment 52