Rethinking Clinical Trials

DECEMBER 3, 2024

In a new report from the NIH Pragmatic Trials Collaboratory, a team of bioethicists explores the ethical obligation to share aggregate results from pragmatic clinical trials with research participants. The article was published online ahead of print in Clinical Trials.

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Rethinking Clinical Trials

DECEMBER 13, 2023

In this Friday's PCT Grand Rounds, Roxana Mehran of the Icahn School of Medicine at Mount Sinai will present "Diversifying Clinical Trials: A Path Forward." Mehran is a professor of medicine and the director of interventional cardiovascular research and clinical trials at the Zena and Michael A.

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Bio Pharma Dive

MAY 19, 2023

The biotech, best known for its vaccine research, said its clinical trial is the first to report results of a messenger RNA therapeutic designed for intracellular protein replacement.

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Rethinking Clinical Trials

NOVEMBER 13, 2024

Delgado is an associate professor of emergency medicine and epidemiology at the University of Pennsylvania and the director of the Penn Medicine Nudge Unit, which “designs and implements scalable nudges to improve medical decision-making and patient outcomes.” ” Join the online meeting. .”

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Bio Pharma Dive

JUNE 17, 2024

Elevate precision medicine: dose optimization and immune monitoring through advanced liquid biopsies.

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Pharmaceutical Technology

MAY 24, 2023

By Luisa Sterkel & Joana Loureiro , Tenthpin Consultants The promise and potential of cell and gene therapies (CGT) has emerged in the recent past and currently over 1.500 CGT are registered for clinical trials holding great hope for the treatment of challenging and uncurable diseases.

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Bio Pharma Dive

NOVEMBER 29, 2022

At a medical conference, the companies detailed clinical trial results that could help support approval of their drug, lecanemab. However, some doctors aren’t yet convinced the medicine’s risks are worth its potential benefits.

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Rethinking Clinical Trials

OCTOBER 16, 2024

Alexander Fanaroff In this Friday’s PCT Grand Rounds, Alexander Fanaroff of the University of Pennsylvania will present “Rigorous Testing of Behavior Change Interventions: Lessons From the BE ACTIVE Randomized Clinical Trial.” Fanaroff is an assistant professor of medicine at the University of Pennsylvania.

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Bio Pharma Dive

NOVEMBER 14, 2024

The company is paying China-based biotech LaNova Medicines $588 million for the type of dual-pronged antibody drug that recently bested Keytruda in a clinical trial.

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Drug Patent Watch

DECEMBER 9, 2024

This intersection is where pharmacognosy meets drug patents, creating a unique landscape that shapes the future of medicine. Let’s embark on a journey to uncover the secrets of nature’s medicine cabinet and the legal frameworks that protect these discoveries.

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Rethinking Clinical Trials

FEBRUARY 12, 2025

ACP PEACE, an NIH Collaboratory Trial, is evaluating a comprehensive advance care planning program for older patients with advanced cancer that combines clinician communication skills training and patient video decision aids. Join the online meeting.

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AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 30, 2024

Researchers see a greater need for new generation therapeutics to propel precision medicine. The development of innovative therapeutic approaches in healthcare encompass a variety of fields, including gene therapy, personalized medicine, immunotherapy, and advanced biologics.

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AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 15, 2024

Some scientists suspect these neural knots can harm and even kill brain cells, but so far in clinical trials, drugs that have tried to target the tangles have shown limited success. A promising new medicine has now […]

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Rethinking Clinical Trials

JANUARY 29, 2025

Skolasky is a professor of orthopaedic surgery and the director of the Spine Outcomes Research Center, and McLaughlin is an assistant professor of physical medicine and rehabilitationboth at the Johns Hopkins University School of Medicine. Join the online meeting.

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Bio Pharma Dive

JANUARY 23, 2023

A high dose of the company’s experimental medicine appeared potent in patients with idiopathic pulmonary fibrosis, an elusive target for drugmakers. The results are from a small and short clinical trial, however.

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Worldwide Clinical Trials

JANUARY 6, 2025

Technological advancements have fostered novel drugs and improved precision medicine, suggesting an increased trend of R&D in this direction. Biomarkers are indispensable tools in clinical trials, providing critical insights that enhance the efficiency and precision of drug development.

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Worldwide Clinical Trials

JUNE 13, 2024

Pharmacogenomics (PGx), the study of how genes affect a person’s response to drugs, has brought significant changes to the clinical trial industry. This high compliance rate is crucial for the successful implementation of personalized medicine, as it ensures a larger and more diverse patient population can benefit from PGx insights.

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Rethinking Clinical Trials

JANUARY 3, 2024

In this Friday's PCT Grand Rounds, Rui Wang of Harvard Medical School will offer the final session in our special series, Advances in the Design and Analysis of Pragmatic Clinical Trials, with "Methods for Handling Missing Data in Cluster Randomized Trials." The session will be held on Friday, January 5, at 1:00 pm eastern.

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Rethinking Clinical Trials

NOVEMBER 6, 2024

Agarwal is an assistant professor of internal medicine and health management and policy at the University of Michigan. The post November 6, 2024: Effects of Income Support on Health and Healthcare Use, in This Week’s PCT Grand Rounds appeared first on Rethinking Clinical Trials. Join the online meeting.

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AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 23, 2024

The medicine behind Ozempic and Wegovy, called semaglutide, could have significant benefits for heart health, reducing the risk of stroke or cardiac arrest even in those who don’t lose weight.

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Bio Pharma Dive

JANUARY 24, 2023

The agency plans to convene a panel of experts on March 22 to discuss the approval application for tofersen, a closely watched medicine Biogen submitted to the FDA despite its failure in a key clinical trial.

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Rethinking Clinical Trials

JANUARY 6, 2025

Fritz is the principal investigator of BeatPain Utah , an NIH Collaboratory Trial, and is a distinguished professor of physical therapy and athletic training and the associate dean for research in the University of Utah’s College of Health. Registration is required for participation this live web conference, but there is no cost.

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Pharmaceutical Technology

JULY 7, 2022

But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine. It is certainly a pivotal moment for the cell and gene industry, with the next decade of R&D and clinical trials expected to transform the future of medicine.

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Worldwide Clinical Trials

MARCH 20, 2024

In the increasingly advancing world of medicine, personalized care is a key factor that can progress your drug development efforts. One way to ensure customized disease management is to utilize pharmacogenomics (PGx) in your clinical trial. Reduces Trial Failures Oftentimes, clinical trials may fail due to a lack of efficacy.

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Camargo

NOVEMBER 22, 2021

In this Q&A, Andrea discusses their experience, especially as it relates to the two clinical trials Tom participated in. We were getting tools to help manage our lives and medicines to manage Tom’s symptoms. We wanted to participate in a clinical trial. How was your husband diagnosed with ALS?

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Velocity Clinical Research

MARCH 23, 2025

Clinical trials have been steadily leaving the UK for years. of patients recruited to global trials were from the UK. Thats not to say we dont still have some clout (the UK ranks fourth globally for Phase II trials ), but the trending outflow needs to be addressed. In 2021, just 2.2%

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Bio Pharma Dive

APRIL 18, 2022

Early analysis of a key clinical trial showed a potentially increased risk of death in cancer patients who received a combination treatment that included TG Therapeutics' approved medicine, Ukoniq.

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AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 17, 2024

Biology is opening up new frontiers in medicine. We are witnessing a revolution in healthcare, driven by advances in genetics, Omics, RNA and CRISPR gene-editing technology, to deliver precision and personalised medicine, said Kiran Mazumdar-Shaw, executive chairperson, Biocon and Biocon Biologics.

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Rethinking Clinical Trials

JANUARY 21, 2025

“Despite this, the development, implementation, and testing of primary palliative care interventions remains a priority, given the workforce shortages in hospice and palliative medicine,” Grudzen said. . Learn more about PRIM-ER.

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Bio Pharma Dive

JULY 9, 2021

Zynteglo sales have been on hold since February, when a patient in a clinical trial of another, related Bluebird medicine developed leukemia.

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Velocity Clinical Research

NOVEMBER 12, 2024

Over the past decade, Germany’s share of global clinical trial activities has dropped year on year. of trials in 2021 , down from 7.2% Aiming to revitalize the country’s pharmaceutical industry, it signaled a shift from policymakers on clinical research and drug development issues. The country accounted for just 3.9%

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pharmaphorum

MAY 24, 2024

Exciting advancements in the world of clinical trials - Arecor Therapeutics, Faron, AstraZeneca, Volta Medical, J&J, Pneumagen, and Nimbus Therapeutics make headlines. Dive into this week's top stories impacting the future of medicine.

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Rethinking Clinical Trials

MARCH 4, 2025

The article was published online in Statistics in Medicine. In stepped-wedge trials, the clusters are randomized into several groups, and all groups start the trial in the control condition. The study was supported by the National Institute on Aging. Learn more about PRIM-ER.

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Worldwide Clinical Trials

OCTOBER 14, 2024

Fortunately, advances in clinical research are providing hope for better treatments and outcomes. With the support of global networks like ours at Worldwide Clinical Trials (Worldwide), autoimmune and bone health research is accelerating, providing new solutions to patients around the world.

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Rethinking Clinical Trials

FEBRUARY 21, 2024

In this Friday’s PCT Grand Rounds, Adrian Hernandez and Christopher Lindsell of Duke University will present “Virtual Vigilance: Monitoring of Decentralized Clinical Trials.” He also serves as co-principal investigator of the NIH Pragmatic Trials Collaboratory Coordinating Center. Join the online meeting.

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Rethinking Clinical Trials

NOVEMBER 16, 2022

Associate Director, Center for Bioethics & Social Sciences in Medicine. Ethics, Data Sharing, Pragmatic Clinical Trials. Kayte Spector-Bagdady, JD, MBioethics. Assistant Professor of Obstetrics & Gynecology. University of Michigan Medical School. Key Points.

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Pharmaceutical Technology

OCTOBER 3, 2024

Eli Lilly has announced a $4.5bn investment to establish the Lilly Medicine Foundry for drug production and manufacturing medicines for clinical trials.

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