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Informatics helps virtual biotech bring compound to clinical trial

Drug Discovery World

With no in-house laboratory space, the company works closely with multiple international contract research organisations (CROs), including Axxam, which carry out all of the Libra R&D, from compound screening assays, to in vivo pharmacokinetic/pharmacodynamic and ADME work, as well as in vitro and in vivo pre-clinical safety assessments.

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AI use in repurposing drugs for Covid-19

Drug Discovery World

But along with this massive disruption came an opportunity: to apply our platform to researching the SARS-CoV-2 virus. This is exactly the type of problem that an AI-powered drug discovery engine is designed to address. In an emerging public health crisis, time is of the essence. That’s where AI and ML come in.

Drugs 59
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

We suggest a new generation of screening assays, that better recapitulate the electrophysiology of the whole human heart, may allow better decisions across research and development. The models chosen can be surprisingly ‘under-evaluated’ given their powerful effect on the quality of research and development decisions.

Drugs 52