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Chemical synthesis: containment challenges for HPAPI handling

Pharmaceutical Technology

These facilities are often multi-use CMO facilities, which combined with the use of HPAPIs, require stringent containment solutions to prevent cross-contamination. Single-use products significantly reduce the time needed for cleaning processes, without the risk of cross-contamination. Chemical synthesis solutions. Free Webinar.

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UK MHRA recalls batches of eye gels due to microbial contamination

Pharmaceutical Technology

The UK MHRA has issued a recall of batches of carbomer-containing lubricating eye gels due to potential microbial contamination.

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'Contaminated' spinach causes hallucinations in Australia

Medical Xpress

Health authorities in Australia have said nine people in Sydney suffered "toxic reactions"—including hallucinations—from a batch of spinach thought to contain an "accidental contaminant".

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How API CMOs can improve containment capabilities without facility acquisition

Pharmaceutical Technology

According to GlobalData analysis, specialist small molecule API capabilities such as containment or controlled substances are driving large contract manufacturing organisations (CMOs) to acquire facilities. Flexible containment solutions for potent APIs. Partnering with containment experts.

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Mitigating the risks of cross-contamination during Oral Solid Dose (OSD) manufacturing

Pharmaceutical Technology

This heightens the risk of cross contamination, requiring effective containment solutions, especially when handling highly potent powders. These include extraction support systems, single-use liquid bags, ArmorFlex Films, continuous liners, contained powder transfer systems, bag in/bag out systems, and drum liners.

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Johnson & Johnson Pulls Neutrogena and Aveeno Spray Sunscreens Over Benzene Contamination

XTalks

Johnson & Johnson is recalling sunscreens from two of its popular brands over concerns of carcinogenic benzene contamination. Therefore, levels should be monitored at different stages of production to avoid harmful benzene contamination. Growing Contamination Issues. Despite this, contamination issues still persist.

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The rising importance of containment in small molecule drug development

Pharmaceutical Technology

Cross-contamination of standard products with highly potent ones is another key concern. On the other hand, the current trend is for fully closed systems that use negative pressure to keep particles contained inside isolators. Many companies are now prioritising investments in containment systems, GlobalData research shows.