Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

Engineer 52

Engineer Genetics Clinical Research Research 52

XTalks

MARCH 22, 2024

According to the EWG, about 95 percent of nonorganic strawberries, certain leafy greens (including spinach, kale, collard and mustard greens), grapes, peaches and pears contain detectable levels of pesticides. Children and farmworkers are among the most vulnerable, and exposure can lead to genetic damage and impaired neurodevelopment.

Contamination 109

Contamination Regulation Containment Genetics 109

XTalks

JULY 26, 2021

Those who seek shorter ingredient lists and cleaner labels may object to plant-based meat due to the many additives and genetically modified proteins that tend to be crucial components of its formulation. Since most plant-based meats contain concentrated protein isolates, consumers may receive much higher doses of potential allergens.

Protein 98

Protein Contamination Allergies Bacteria 98

Roots Analysis

JANUARY 27, 2025

Cell therapies are based on the premise that the patients own cells (autologous), or those from a healthy donor (allogeneic), can be genetically re-programmed to combat various diseases. Such procedures require sterile and higher-grade clean rooms, along with regular checks on containment levels.

Manufacturing 40

Manufacturing Contamination Production Gene Therapy 40

Roots Analysis

OCTOBER 24, 2023

They consist of two or more amino acids and are synthesized naturally from transcription of a sequence of genetic code. This precaution is taken to prevent any potentially harmful contaminant from escaping the production area. This is in contrast to the containment requirements at manufacturing facilities of traditional APIs.

Manufacturing 40

Manufacturing Hormones Contamination Containment 40

Roots Analysis

SEPTEMBER 18, 2023

Due to the infrastructure available for processing, freezing and storing of these container systems, blood bags are the preferred container for cell therapy biopreservation. The above figure presents a general overview of the cryopreservation process.

Engineer 52

Engineer Containment In-Vivo Production 52

Roots Analysis

APRIL 15, 2024

Over the years, these large molecules have demonstrated promising therapeutic outcomes in the treatment of myriad of chronic and challenging disorders, including autoimmune disorders, infectious diseases, genetic disorders, and oncological disorders.

Manufacturing 40

Manufacturing Production Contract Manufacturing Contamination 40