Scienmag

APRIL 23, 2021

Credit: Gemma Lofthouse An international team of researchers led by the University of Bergen has uncovered how organisms from crops to corals may avoid deadly DNA damage during evolution. Our cells, and those of animals, plants and fungi, contain compartments that produce chemical fuel.

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DNA Containment Research Genetics 89

Scienmag

OCTOBER 13, 2020

Researchers find that simple DNA-peptide interactions create a surprising diversity of compartmentalised higher-ordered phase behaviours, suggesting that these polymers’ primordial interactions helped create modern complex biological structures. For example, each human cell contains about 2 meters worth of DNA, but this is […].

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STAT News

OCTOBER 12, 2022

From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

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DNA Containment Scientist Medicine 144

Scienmag

SEPTEMBER 17, 2020

They have to precisely divide to form new specialized cells, which are destined to different fates even though they contain identical DNA. Credit: Andrew Muroyama The stem cells tasked with creating and maintaining biological tissues have a difficult job.

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Pharmaceutical Technology

JUNE 14, 2023

Basic human traits such as eye and hair colour are determined by our DNA. metres of supercoiled DNA contained within its nucleus. If you were to uncoil all the DNA in your body into a single continuous strand it would be 54 trillion metres in length, enough to stretch from the Earth to the Sun and back 180 times.

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Genome Project Medicine Genomics Genome 130

Scienmag

OCTOBER 22, 2020

When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Poop contains very precise information about the prey […]. For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species.

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Scienmag

JULY 14, 2021

Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles Credit: Mindy Takamiya/Kyoto University iCeMS Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The findings, by scientists at Kyoto […].

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Pharmaceutical Technology

MARCH 28, 2023

In 2021, the FDA gave Jemperli an accelerated approval for the treatment of adult patients with mismatch repair deficient (dMMR) recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing regimen. These cells are prone to DNA mutations that can often lead to cancer.

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Medical Xpress

FEBRUARY 28, 2025

The human genome contains viral DNA that was integrated into the genomic code long ago. A subset of these viral genes can still be reactivated under certain circumstances to produce viral proteins.

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Scienmag

APRIL 8, 2021

This full assembly may contain clues to ape and human divergence; certain immune, brain and heart disorders; and other biomedical questions Credit: Kendra Hoekzema The full assembly of human chromosome 8 is reported this week in Nature.

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pharmaphorum

SEPTEMBER 14, 2021

Startup Rome Therapeutics has raised $77 million in second-round financing to help mine sequences of DNA – which were dismissed for years as ‘junk’ – for hidden treasure. Much of this repeatome is thought to derive from viruses that embedded in our DNA millions of years ago.

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Medical Xpress

FEBRUARY 13, 2023

The gut microbiota contains trillions of bacteria that can promote health or cause disease under different conditions. The collective DNA sequences that make up the bacteria flora, is called the microbiome.

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Bacteria DNA Containment Research 75

Scienmag

NOVEMBER 15, 2021

Cell biologists track this process by observing chromosomes—structures made of DNA that contain the genetic material of an organism. Cell division is an important process that underlies biological growth and repair. However, their analysis is still […].

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DNA Containment Genetics Research 83

Scienmag

JUNE 29, 2022

The sub-basement Collections Resource Center houses millions of biological specimens for scientists around the world to use in their research, including countless bottles and jars containing pickled fish, lizards, and snakes, arranged like a library. Many of these specimens are decades or even centuries old, […].

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Scienmag

OCTOBER 27, 2021

Carbon is the cornerstone of most biologically produced organic compounds such as proteins, carbohydrates, fats and DNA. All of these compounds contain, in addition to carbon, many other […]. Through the course of evolution, living organisms have learned to form and process large numbers of different carbon compounds.

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Scienmag

JUNE 13, 2022

The legible sections contained the code for making cell proteins; the other regions, representing about 90% of the entire genome, were dismissed as “junk DNA,” […].

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Scienmag

MAY 11, 2022

NEW YORK CITY, May 11, 2022 – Credit: Memorial Sloan Kettering Cancer Center NEW YORK CITY, May 11, 2022 – Many cancers contain similar genetic “hotspots” — areas of DNA that are likely to be mutated. For example, more than 50% of cancers contain a mutation in a gene called TP53, often within a narrow DNA […].

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Pharmaceutical Technology

OCTOBER 26, 2022

Gene therapy uses DNA to manipulate cells and correct defective genes, whereas cell therapy is the infusion or transplantation of cells into a patient. New doors were opened in the 2000s with the development of genome editing, such as CRISPR-Cas9, which introduces molecular tools to change existing DNA.

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XTalks

MAY 4, 2021

The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without changing the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.

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Scienmag

MAY 2, 2022

Every plant, animal or other nucleus-containing cell also harbors an array of miniature “organs” that perform essential functions for the cell. Because some organelles contain their own DNA and resemble single-celled organisms, scientists have long theorized that the […]. CHAMPAIGN, Ill.

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Roots Analysis

OCTOBER 16, 2023

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence.

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Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

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Scienmag

SEPTEMBER 22, 2021

A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important distinction for containing viral spread. CHAMPAIGN, Ill. — Credit: Image courtesy of Ana Peinetti CHAMPAIGN, Ill. — A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important […].

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Scienmag

OCTOBER 7, 2020

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications DNA and RNA have been compared to “instruction manuals” containing the information needed for living “machines” to operate.

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Scienmag

JULY 3, 2022

Researchers who treated a group of post-surgery bladder cancer patients with the immunotherapy drug atezolizumab have found that patients whose blood contained circulating tumour DNA (ctDNA), responded very well to the treatment. The study is presented today at the European Association of Urology annual congress (EAU22), in Amsterdam.

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DNA Containment Research Drugs 67

Scienmag

SEPTEMBER 14, 2021

The term ‘DNA’ immediately calls to mind the double-stranded helix that contains all our genetic information. But the individual units of its two strands are pairs of molecules bonded with each other in a selective, complementary fashion.

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DNA Gene Containment Genetics 40

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. The vaccine also contains other inactive ingredients such as cholesterol.

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XTalks

JANUARY 21, 2025

The liquid portion of the blood (serum or plasma) containing antibodies is separated and tested using the Liason Biotrin parvovirus B19 IgG plus test on a Liason XL analyzer. The Shield test provides a non-invasive approach to colorectal cancer screening by analyzing blood for key DNA changes linked to cancer. Photo courtesy of BD.

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XTalks

AUGUST 10, 2021

Moreover, studies show that saliva samples can contain a marginally higher SARS-CoV-2 viral load compared with nasopharyngeal samples (shown in a study involving hospitalized patients), and that the virus can be detected in saliva for a greater number of days post-infection. A porous membrane was engineered to capture RNA on its surface.

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Scienmag

OCTOBER 6, 2021

In the cell’s power plants, known as mitochondria, the energy contained in our food is converted into the molecule ATP. It serves as a kind of fuel that drives most cellular processes – from muscle contraction to the assembly of our DNA. In order to fulfill their many tasks, cells need energy.

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pharmaphorum

AUGUST 5, 2021

Critical cellular processes including DNA replication and translation cannot occur without functional-specific proteins. Whereas targets like receptors contain an obvious ligand-binding site for drug molecules to interact with, PPIs comprise a more complex structure. Current challenges and conventional approaches in targeting PPIs.

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XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We

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The Pharma Data

DECEMBER 23, 2020

” Dr. Stanley Plotkin , Professor Emeritus at The Wistar Institute, said, “INOVIO’s DNA vaccine appeared to be quite safe with few significant reactions but yet induced both antibody and T cell responses to SARS-CoV-2.” About INOVIO’s DNA Medicines Platform. mg and 2.0

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FDA Law Blog

DECEMBER 8, 2022

Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., airlines).

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BioTech 365

JULY 15, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers use laser ‘tweezers’ to study structure and dynamics of chromatin.Each one of the cells in our body contains DNA, which provides the instructions required for our … Continue reading →

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Roots Analysis

MARCH 1, 2023

Disruption of the integrity and function of DNA at the gene or chromosomal level can lead to heritable mutations, resulting in genetic disorders, birth abnormalities, or cancer. Mechanism of Genotoxicity / Mutagenicity The interaction of genotoxins / mutagens with the structure of DNA causes damage to the genetic material.

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Genotoxicity DNA Genetics Bacteria 52

pharmaphorum

MAY 11, 2021

Laronde thinks that its new class of RNA – a transcript of DNA that can be read by the body and turned into proteins – will cut the number of injections required as the body will actively make the disease-fighting protein instead of passively requiring top-ups.

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