BioTech 365

DECEMBER 17, 2021

Endothelial PAS Domain-Containing Protein 1 Inhibitors – 2021 Pipeline Landscape Report with Insights on 7+ Companies and Drugs – ResearchAndMarkets.com Endothelial PAS Domain-Containing Protein 1 Inhibitors – 2021 Pipeline Landscape Report with Insights on 7+ Companies and Drugs – ResearchAndMarkets.com … Continue reading (..)

Containment 40

Containment Protein Drugs 40

Pharmaceutical Technology

JUNE 21, 2023

In the past year, Hemgenix has been granted approval by the US Food and Drug Administration (FDA) and has received conditional marketing authorisation from the European Commission (EC) and the UK’s Medicines and Healthcare products Regulatory Agency (MHRA).

Gene Therapy 246

Gene Therapy Gene Protein Sales 246

XTalks

AUGUST 27, 2021

Renegade Creamery makes plant-based cheese but adds milk proteins produced in strains of yeast and bacteria and uses an “artisan fermentation process.” Like Renegade Creamery, the company also uses transgenic bacteria and yeast to make the protein because they have a history of being a safe and reliable way of producing animal proteins.

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Production Protein Containment Branding 98

Pharmaceutical Technology

MARCH 14, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology in Pharmaceuticals: Purine derivatives-based cancer drug compositions. By means of geographic reach, Primmune Therapeutics Inc holds the top position.

Drugs 130

Drugs Protein Research Containment 130

Pharmaceutical Technology

JANUARY 24, 2023

The US Food and Drug Administration (FDA) has granted clearance for Neurogene’s investigational new drug (IND) application for NGN-401 to treat Rett syndrome. Developed with the University of Edinburgh, the EXACT self-contained technology enables MeCP2 protein therapeutic levels while avoiding overexpression-related toxicities.

Gene Therapy 208

Gene Therapy Gene Gene Expression Regulation 208

Scienmag

NOVEMBER 20, 2020

It contains the information for the production of 27 proteins. This is not much compared to the possible 40,000 kinds of protein that a […].

Genome 70

Genome Genomics RNA Protein 70

Pfizer

JULY 26, 2022

Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design. Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design. deliesschef. Tue, 07/26/2022 - 17:41.

Vaccine 111

Vaccine Vaccination Protein Immune Response 111

XTalks

JULY 28, 2020

Excipients can take many forms, such as bulking agents, binders, coatings and colourants, and they are chosen based on their ability to aid in drug delivery, administration and even in pill identification and prevention of counterfeiting. But just how inert are these excipients?

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Protein Drugs In-Vitro Scientist 103

The Pharma Data

MARCH 23, 2022

Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives. The researchers discovered that Ebola virus polymerase hijacks a cellular protein called GSPT1. Catching polymerase in the act.

Protein 52

Protein Genomics Genome Research 52

FDA Law Blog

JULY 11, 2023

Koblitz — One of the most important questions FDA has to answer is whether a given product is appropriately characterized as a drug, biologic, device, food, cosmetic, or something entirely different. FDA further defined the term “protein” so that it includes any peptide product that has an amino acid sequence greater than 40 amino acids.

Protein 95

Protein Production Regulation Cosmetics 95

Worldwide Clinical Trials

SEPTEMBER 29, 2022

Preclinical assays designed to assess drug toxicity and safety must detect total drug. For studies of humanized therapeutics (monoclonal antibodies [mAb], fusion protein, antibody-drug conjugates [ADC], bispecific antibodies, etc.), To measure free drug only, anti-idiotype (anti-ID) mAb testing may be the best choice.

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Reagent Clinical Trials Clinical Trials Antibody 130

Pharmaceutical Technology

APRIL 16, 2023

Autoinjectors have revolutionised the convenient delivery of low-volume parenteral drugs. But with the advent of injection site absorption enhancers, drug delivery device innovations, as well as the recent primary container options, the practical subcutaneous self-administration of large-volume parenterals is becoming possible.

Protein 130

Protein Containment Drug Delivery Drugs 130

Scienmag

DECEMBER 9, 2021

When the body attempts to fight off an infection, immune cells called neutrophils may shoot out spider web-like networks of toxic proteins to help contain the invaders.

Immune Response 60

Immune Response Containment Protein Regulation 60

XTalks

MAY 13, 2022

A container closure system consists of all the packaging components that contain and protect a pharmaceutical product. Container Closure Systems. A container closure system protects the product from environmental conditions, safeguarding a product’s purity, strength, safety and efficacy.

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Packaging Packaging Containment Production 98

The Pharma Data

MARCH 30, 2021

Basel, March 30, 2021 — Novartis has obtained exclusive worldwide rights to develop and commercialize therapeutic applications for a library of Fibroblast Activation Protein (FAP) targeting agents including FAPI-46 and FAPI-74, through an assignment agreement with iTheranostics, Inc., an affiliate of SOFIE Biosciences, Inc. Disclaimer.

Protein 52

Protein Licensing Licensing Containment 52

The Pharma Data

AUGUST 15, 2021

Food and Drug Administration were based on mRNA, more conventional protein-based vaccines have also shown promise in clinical trials. Most train the immune system to recognize the RBD, a peptide that is the portion of the SARS-CoV-2 spike protein that binds to the ACE-2 receptor on host cell surfaces. bioRxiv [Preprint].

Protein 52

Protein Vaccine Vaccination Antibody 52

Scienmag

JUNE 3, 2022

Researchers at Baylor College of Medicine and Texas Children’s Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The team reports in the Proceedings of the […].

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Containment Protein Medicine Development 64

pharmaphorum

OCTOBER 2, 2020

The rolling review, which is designed to speed up the assessment of a promising vaccine or drug by the EMA’s CHMP scientific committee, will continue until there is enough evidence available to support a marketing authorisation. But this does not mean that the CHMP is ready to make a conclusion on the safety and efficacy of the vaccine.

Regulation 105

Regulation Vaccine Vaccination Protein 105

XTalks

APRIL 22, 2021

While Clara Foods, a leader in animal-free proteins, worked for years to replicate the taste, function and proteins of eggs without the chickens, scaling the product has been difficult — until now. Making Animal-Free Eggs. The same can be said for lab-grown meat. The same can be said for lab-grown meat.

Protein 98

Protein Production Manufacturing Regulation 98

pharmaphorum

SEPTEMBER 28, 2020

VWD affects up to 1% of the global population, and is caused by deficiency or dysfunction in the protein known as von Willebrand factor (VWF). Also, unlike many pdVWF products, Veyvondi does not contain any clotting Factor VIII, so that co-dosing does not need to be accounted for and the risk of excess factor building up is reduced.

Drugs 69

Drugs Containment Production Protein 69

FDA Law Blog

DECEMBER 8, 2022

Food and Drug Administration (FDA) issued two guidance documents, one draft and one final, on food allergen labeling requirements. labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. By Sophia R. Gaulkin — Last week, the U.S.

Genetic Engineering 59

Genetic Engineering Containment Cosmetics Protein 59

XTalks

JULY 8, 2021

Along with a team of scientists, Kozubel fermented the microbe into a protein-rich substance and dubbed it “Fy.” While many faux meats tend to use soy, pea and other plant-based proteins, Fy is the foundation of Nature’s Fynd products. Fy also contains 50 percent more protein than tofu and has a fraction of the fat of ground beef.

Protein 98

Protein Production Branding Marketing 98

Camargo

APRIL 28, 2021

A good, informative model explores the influence of different covariates such as body weight and age to explain the variability in drug response and uses these covariates to translate PK information to children. If the model does not contain covariates relevant for young patients, they are added to the model based on the known information.

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Clinical Trials Clinical Trials In-Vivo Drugs 130

XTalks

JANUARY 3, 2024

Wainua is the only FDA-approved drug for the treatment of ATTRv-PN that can be self-administered via an auto-injector. In individuals affected by ATTR, which includes both hereditary and wild-type (non-hereditary) variants, the TTR protein forms fibrils that accumulate in various tissues.

FDA Approval 105

FDA Approval Protein RNA Clinical Trials 105

XTalks

DECEMBER 5, 2023

The US Food and Drug Administration (FDA) has granted approval for Bristol Myers Squibb’s (BMS) Augtyro (repotrectinib), marking a significant milestone for the treatment of adult patients with locally advanced or metastatic ROS1 -positive non-small cell lung cancer (NSCLC).

Protein 115

Protein FDA Approval Medicine Trials 115

The Pharma Data

DECEMBER 16, 2020

Currently in Phase 3 clinical testing in the United Kingdom for the prevention of COVID-19, NVX-CoV2373 is a recombinant protein vaccine adjuvanted with Novavax’ proprietary Matrix-M to enhance the immune response. NVX-CoV2373 contains purified protein antigen and can neither replicate, nor can it cause COVID-19.

Protein 52

Protein Vaccine Vaccination Immune Response 52

The Pharma Data

DECEMBER 16, 2020

TWO NOVEL SOLID TUMOUR TARGETS FROM THE PARTNERSHIP TRANSITION INTO DRUG DISCOVERY. This has enabled the generation of a pipeline of novel first-in-class targeted protein degradation projects. Evotec will be responsible for progressing the drug discovery programmes to IND filing.

Protein 40

Protein Bioinformatics Containment Drugs 40

Pharmaceutical Technology

AUGUST 22, 2022

Softgel capsules, containing a liquid, paste or emulsion active ingredient, are trusted and favoured by many patients. Fixed-dose combination (FDC) systems aim to increase patient compliance in therapies involving two or more active drugs. The best formulation for the job.

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Compliance Bioavailability Containment Branding 130

The Pharma Data

JANUARY 13, 2021

Food and Drug Administration (FDA) has granted Orphan Drug Designation for HPN217 for the treatment of multiple myeloma. HPN217, a tri-specific T cell activating recombinant protein construct (TriTAC®) targets B-cell maturation antigen (BCMA), a well-validated antigen expressed on malignant multiple myeloma cells.

Drugs 52

Drugs Clinical Trials Clinical Trials Containment 52

pharmaphorum

AUGUST 16, 2020

The advance order will be financed using the EU’s Emergency Support Instrument, a €2 billion fund set aside to cover purchases of vaccines, drugs and other goods needed to fight the coronavirus epidemic.

Vaccine 111

Vaccine Vaccination Immune Response Trials 111

XTalks

FEBRUARY 20, 2024

The vaccines received approvals from the US Food and Drug Administration (FDA) in May 2023 for the prevention of RSV infection. Type of Vaccine Arexvy and Abrysvo are both recombinant protein subunit vaccines. Another difference is that Arexvy contains an adjuvant while Abrysvo does not.

Vaccine 105

Vaccine Vaccination Containment Marketing 105

pharmaphorum

AUGUST 6, 2020

The FDA has approved GlaxoSmithKline’s multiple myeloma drug Blenrep, a first-in-class potential blockbuster that will be used in advanced disease. This is an accelerated approval based on response data and GSK may need survival data from a larger trial to keep the drug on the market in the longer term.

FDA Approval 87

FDA Approval Antibody Drugs Packaging 87

XTalks

AUGUST 6, 2020

The US Food and Drug Administration (FDA) has approved the use of an oral cannabidiol (CBD) solution called Epidiolex for the treatment of seizures associated with tuberous sclerosis complex (TSC) in patients aged one year and older. Epidiolex is the only FDA-approved formulation that contains CBD derived from the cannabis plant.

FDA Approval 64

FDA Approval Protein Containment Genetic Disease 64

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. On one hand, unfortunately this means that many drugs are doomed to failure. Now, however, the field is changing with respect to genomic medicine.

Genomics 119

Genomics Genome Medicine Gene 119

The Pharma Data

JANUARY 31, 2021

Ion channels represent a large but under-exploited class of drug targets beyond G protein-coupled proteins (GPCRs). Collaboration combines Sosei Heptares’ leading structure-based drug design platform with Metrion Biosciences’ ion channel expertise.

Drugs 52

Drugs Protein In-Vitro Development 52

Delveinsight

OCTOBER 1, 2021

This disease is associated with antibodies directed against the acetylcholine receptor, muscle-specific kinase (MUSK), lipoprotein-related protein 4 (LRP4), or agrin in the postsynaptic membrane at the neuromuscular junction. The current Myasthenia Gravis therapeutics market has many FDA-approved drugs for the treatment of Myasthenia Gravis.

Marketing 85

Marketing Antibody Drugs Sales 85

XTalks

JULY 1, 2021

Now the vaccine maker is awaiting the same approval from the US Food and Drug Administration (FDA). It partnered on over 75 percent of approved drug names in 2020. The name contains two syllables, the first referencing the spike protein of SARS-CoV-2, and the second a short-form of the word “vaccine.”. “At

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Branding Vaccine Vaccination Clinical Trials 98