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According to GlobalData analysis, specialist small molecule API capabilities such as containment or controlled substances are driving large contract manufacturing organisations (CMOs) to acquire facilities. Flexible containment solutions for potent APIs. Partnering with containment experts.
Fuller, Sayo Studio The interiors of nonflowering trees such as pine and ginkgo contain sapwood lined with straw-like conduits known as xylem, which draw water up through a tree’s trunk and branches. Prototypes tested in India show promise as a low-cost, natural filtration option Credit: Courtesy: N.R.
According to Adam Bradbury, GlobalData PharmSource analyst “[…] evidence indicates that containment facilities are in high demand and will be increasingly so in future as the oncology pipeline and the use of cytotoxic drugs continues to grow.” These turnkey solutions cover every process through the drug manufacturing life cycle.
In a first, the digital fiber contains memory, temperature sensors, and a trained neural network program for inferring physical activity Credit: Image: Anna Gittelson. Photo by Roni Cnaani. MIT researchers have created the first fiber with digital capabilities, able to sense, store, analyze, and infer activity after being sewn into a shirt.
Research by GlobalData (Contract Small Molecule API Manufacturing Industry by the Numbers – 2021 Edition) shows that containment facilities are in high demand as the use of cytotoxic drugs continues to grow. Adding to these factors is that oncology accounts for the majority of marketed, contained drugs. Containment challenges.
What if you could tell if your surroundings contained COVID-19 particles or droplets the moment they or you entered the vicinity? A research group has engineered a batteryless, self-powering device that can wirelessly transmit the detection of coronavirus in the air. This is now closer to reality.
The download contains detailed information on the providers and their services and solutions, alongside contact details to aid your purchasing or hiring decision. Rise of pharma cold chain logistics companies. The post Leading pharmaceutical logistics and pharma supply chain companies appeared first on Pharmaceutical Technology.
Photo by Raysonho @ Open Grid Scheduler / Grid Engine. Some supplements billed as ‘smart drugs’ may contain unapproved drugs in potentially dangerous combinations and doses, according to a new study. The FDA may take action against a supplement maker after a product is on the market if it is mislabelled or contains unapproved drugs.
NEWS RELEASE Credit: Alvarez Research Lab/Rice University NEWS RELEASE Jeff Falk 713-348-6775 jfalk@rice.edu Mike Williams 713-348-6728 mikewilliams@rice.edu Microplastic pollution aids antibiotic resistance Engineers at Rice lead study of how polystyrene contributes to crisis HOUSTON – (Dec.
Successful TIL therapy depends on the infusion product containing tumour-reactive T cells that, on infusion, generate an anti-tumour immune response that causes disease regression. The use of engineered immune cytokines that selectively induce the expansion of TILs is being investigated as an alternative to IL-2 stimulation.
The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials. Why Does the IBC Need to do a Risk Assessment?
Hemgenix works by dosing a patient with an engineered adeno-associated virus (AAV), containing the gene responsible for producing a protein called factor IX. This protein helps to form blood clots and stop bleeding, with haemophilia B arising when the body is partially or completely unable to produce it.
The download contains detailed information on the providers and their services and solutions, alongside contact details to aid your purchasing decision. The AI engine predicts and identifies patients who are at risk and optimises interventions for them by channel, messages and timing. Patient adherence.
Study explores flushing power to test risk of COVID-19 transmission Credit: Florida Atlantic University, College of Engineering and Computer Science Flushing a toilet can generate large quantities of microbe-containing aerosols depending on the design, water pressure or flushing power of the toilet.
The information contained within the download document is designed for pharmaceutical executives, marketing managers, product managers, sales and marketing executives, medical representatives, software engineers, developers, business development executives and any other individual involved in the direct-to-consumer pharmaceutical marketing industry.
The document contains detailed information on the suppliers and their product offerings, alongside contact details to aid your purchasing decision. Role of freeze-drying systems in the pharmaceutical industry The pharmaceutical freeze-drying market is highly governed by stringent standards and laws.
Genetics toolkit targets less researched Culex mosquitoes, which transmit West Nile virus and avian malaria Credit: Gantz Lab, UC San Diego Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and (..)
“Adalvo brings to the table its regulatory expertise and then will put its extensive commercial engine to work with a view of laying out a globalisation roadmap for Mellozzan. Mellozzan contains the sleep hormone melatonin and is indicated for use in children with attention deficit hyperactivity disorder (ADHD) and sleep difficulties.
Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Sheng Professor of Biomedical Engineering. ” An Effective On/Off Switch.
Resembling silica gel packets found in certain food and commercial products, SAVRPak’s frozen peel-and-stick patches can be placed inside most delivery containers — including clamshell containers, pizza boxes and paper bags — to remove moisture and reduce humidity.
Researchers at Massachusetts Institute of Technology (MIT) have designed the world’s first digital fabric fiber that contains digital devices which can sense, analyze and store health data, and use it to infer a person’s activity and state of health. The digital fibers can be sewn into clothing to help monitor bodily functions.
ILC Dover is a leader in the innovative design and production of containment solutions for biopharmaceutical and pharmaceutical markets, including its single-use liquid bags. One element of streamlining manufacturing methods includes finding the best equipment to optimise processes, which is driving the development of various innovations.
ILC Dover, specialists in the innovative design of biopharmaceutical manufacturing solutions, continuously monitors the market in order to provide in-demand equipment such as flexible containment solutions that reduce bottlenecks by providing closed, Grade-A, aseptic environments for fill and finish activities.
The test was developed by researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University, the Massachusetts Institute of Technology (MIT) and several Boston area hospitals. However, unprocessed saliva contains enzymes that degrade various molecules, which can lead to a high rate of false positives.
Ltd (“ CIMC Sanctum “) recently started R&D of liquid nitrogen biological containers for long-term cryogenic storage of vaccines, stem cells, plasma, semen, embryos and various tissues and organs for the needs of the biomedical industry. SHENZHEN, China , Jan. ” About CIMC Enric Holdings Limited.
Credit: Edel Pérez-López First described in the 13th century in Russia, clubroot has been affecting worldwide brassica production, including canola, broccoli, and black mustard, since.
Best practices include the use of containedengineering solutions to safeguard drug product integrity and protect operators. Another critical challenge lies in selecting appropriate container closure systems for liquid formulations. These systems must prevent breakage and avoid interactions with the formulation.
Credit: Osaka University Researchers at Chinese Academy of Science and Osaka University show that, unlike the crystalline close packing of spheres, random close packing or jamming of spheres in a container can take place in a broad range of densities and anisotropies.
Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles Credit: Mindy Takamiya/Kyoto University iCeMS Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The findings, by scientists at Kyoto […].
Credit: LI Sushuang Nanofiltration (NF) is an advanced technology for treating wastewater containing organic micropollutants (OMPs). WAN Yinhua from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences developed a stable graphene oxide nanofiltration membrane with uniform pore size to remove OMPs.
Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers.
Xencor overview Xencor is a clinical stage biopharmaceutical company that focused on discovering and developing engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The drug candidate is being developed based on XmAb technology.
Xencor overview Xencor is a clinical stage biopharmaceutical company that focused on discovering and developing engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The drug candidate is being developed based on XmAb technology.
Xencor overview Xencor is a clinical stage biopharmaceutical company that focused on discovering and developing engineered monoclonal antibody and cytokine therapeutics to treat patients with cancer and autoimmune diseases. The drug candidate is being developed based on XmAb technology.
Breakthroughs in therapies containing monoclonal antibodies (mAbs) are showing ever-greater potential in treating a range of diseases, alongside biopharma manufacturers facing the challenge of keeping up with demand for production while controlling costs. Increasing product yield is the most fundamental way to achieve this.
labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., Other technical labeling matters.
The human health is suffering from effluent containing heavy metal ions (such as Cr(VI)) and organic dyes (such as rhodamine B). Among numerous strategies to remove pollutants from water, photocatalysis has attracted extensive attention due to its low energy consumption, simple operation and environmental friendliness.
A loaded syringe can be safely capped using either: A safety engineered syringe. Tools or special sharp containers to remove the needle and replace with a fresh and already capped needle. All potentially infectious sharps must be disposed of in a biohazard sharps container immediately after use without recapping.
West Virginia University is launching a toxicology training program that offers students something no other academic program does: experience collecting air samples, identifying the toxicants they contain and determining how those toxicants might harm a community’s health.
The products contain ingredients like bamboo fiber, pea protein and mushrooms. The study also highlights how genetically engineered microorganisms can inhibit the growth of foodborne pathogens. Additionally, the offerings have the distinctive “snap” of the outer casing and the savory smokiness of Oscar Mayer products.
Voyage Foods, a California-based startup that has reverse-engineered chocolate, peanut butter and coffee, recently closed a $36 million Series A investment round, bringing the company’s total funding to $41.8 Its peanut-free peanut butter contains sunflower seeds, chickpeas, grapeseed, buckwheat and wild rice.
The expanding production of high potency APIs, along with the increase in associated toxicities, are driving requirements for more effective containment solutions and much-needed guidelines to ensure worker safety. Assess engineeringcontainment controls, from isolators and barriers to fully automated lines.
The test involves the use of testing strips that contain a glucose biosensor with electronic elements in the test’s transistor, like inks, that allow for mass printing of the test strips at low cost. The saliva test contains a glucose biosensor coated with the enzyme glucose oxidase and an electronic transistor. Biosensor Technology.
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