Pharmaceutical Technology

JUNE 14, 2023

However, more immeasurable characteristics such as personality, behaviour, and even intelligence are all influenced by genetics to varying degrees. metres of supercoiled DNA contained within its nucleus. Despite its historic nature, the Human Genome Project had many setbacks, the greatest among them being the lack of genetic diversity.

Genome Project 130

Genome Project Medicine Genome Genomics 130

Pharmaceutical Technology

DECEMBER 12, 2022

It leverages the new D-Domain binder of Arcellx and contains autologous T cells genetically modified for targeting multiple myeloma. An investigational late-stage product candidate, CART-ddBCMA is being analysed in the Phase II iMMagine-1 clinical trial at present.

Development 264

Development Gene Therapy Clinical Trials Clinical Trials 264

Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials.

Engineer 52

Engineer Genetics Clinical Research Research 52

Scienmag

NOVEMBER 15, 2021

Cell biologists track this process by observing chromosomes—structures made of DNA that contain the genetic material of an organism. Cell division is an important process that underlies biological growth and repair. However, their analysis is still […].

DNA 83

DNA Containment Genetics Research 83

Pharmaceutical Technology

FEBRUARY 15, 2023

The active component of the Pfizer-BioNTech vaccine tozinameran, contains the genetic code for the coronavirus spike protein, inside a lipid (fat) capsule. The vaccine also contains other inactive ingredients such as cholesterol.

Vaccine 130

Vaccine Vaccination Containment Immune Response 130

Scienmag

OCTOBER 4, 2020

CHICAGO – Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. DNA, which carries genetic information in cells, contain biological instructions. A genetic mutation, which is a permanent […].

Genetics 40

Genetics Research DNA Containment 40

Pharmaceutical Technology

MAY 24, 2023

The ability to modify or introduce genetic material in human cells in such a precise and patient-centered manner clearly constitutes a breakthrough in personalized medicine. CGT drugs fall into two major categories: autologous and allogeneic. This is a primary factor for the staggeringly high unit cost of CGT.

Clinical Trials 246

Clinical Trials Clinical Trials Gene Therapy Clinical Supply Chain 246

The Pharma Data

NOVEMBER 19, 2020

MD, FAAP, Cincinnati Children’s Hospital, who will discuss genetic forms of hearing loss in children. Dr. John Greinwald is a tenured professor of Otolaryngology and Pediatrics with over 20 years of experience with a focus on the genetic causes and treatment of deafness. To register for the call, please click here. Disclaimer.

Genetics 52

Genetics Containment Genetic Disease Gene 52

XTalks

OCTOBER 8, 2024

A gene contains instructions within our DNA. Today, it’s known that the human genome encodes over a thousand microRNAs, which play vital roles in how organisms grow, differentiate and operate, uncovering a new layer of complexity in genetic regulation.

Regulation 52

Regulation Genetics Scientist RNA 52

Scienmag

NOVEMBER 20, 2020

Scientists at Goethe University within the international consortium COVID19-NMR refine previous 2D models The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains the information for the production of 27 proteins.

Genomics 70

Genomics Genome RNA Protein 70

Scienmag

MAY 7, 2021

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling […]. (..)

DNA 62

DNA Regulation Genomics Genome 62

The Pharma Data

JULY 8, 2021

Today, access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. PFIZER DISCLOSURE NOTICE: The information contained in this release is as of July 8, 2021.

Genetics 52

Genetics Biobanking Protein Containment 52

Pharmaceutical Technology

SEPTEMBER 20, 2022

The production of commercial dose non-sterile products such as tablets, capsules, ointments, creams, and powders is rising due to their growing global demand, attributed to increasing demand for anti-ageing products, hereditary factors, genetic mutations, exposure to harmful radiation, and rising geriatric population.

Marketing 100

Marketing Drug Delivery Systems Production Containment 100

Scienmag

APRIL 23, 2021

Our cells, and those of animals, plants and fungi, contain compartments that produce chemical fuel. These compartments contain their own DNA, which stores instructions for important […].

DNA 89

DNA Containment Research Genetics 89

Pharmaceutical Technology

AUGUST 5, 2022

But 10% of the cases are caused by genetic factors, meaning patients inherit the condition through familial links. Since research needs to be done under containment conditions, samples cannot be moved across different facilities, he explains. Adding to this, the infectivity of prion diseases also makes research challenging, says Wille.

Drugs 299

Drugs Protein Vaccine Vaccination 299

STAT News

OCTOBER 12, 2022

From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

DNA 144

DNA Containment Scientist Medicine 144

The Pharma Data

JULY 15, 2021

The access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE). About the UK Biobank.

Biobanking 52

Biobanking Genetics Protein Medicine 52

Scienmag

FEBRUARY 19, 2021

Undergraduate students explore a more efficient way to measure protein-containing vessels released by cells Credit: DGIST Despite our great progress in understanding various cellular mechanisms over the last decades, many of them remain unclear.

RNA 52

RNA Containment Protein Genetics 52

XTalks

DECEMBER 23, 2024

Research shows how mosquito genetics, combined with expanding habitats due to climate change , may accelerate the risk of Zika virus outbreaks, emphasizing the urgency of targeted vector control strategies. The WHO contained a Marburg virus outbreak in Tanzania in early 2024 with nine cases and six deaths.

Vaccine 52

Vaccine Vaccination Containment Bacteria 52

The Pharma Data

DECEMBER 28, 2020

About Fulgent Genetics. Fulgent Genetics’ proprietary technology platform has created a broad, flexible test menu and the ability to continually expand and improve its proprietary genetic reference library while maintaining accessible pricing, high accuracy and competitive turnaround times. TEMPLE CITY, Calif.,

Genetics 52

Genetics Sales Gene Sequencing Marketing 52

Medical Xpress

MAY 9, 2023

Leucine-rich repeats containing 4 (LRRC4)—a gene abundantly found in the brain and located on human chromosome 7q31–32—plays a pivotal role in memory formation, autism, spinal cord injury, as well as in determining the malignant potential, development, and progression of glioblastoma (GB), an aggressive cancer involving the brain and/or spinal cord. (..)

Gene 100

Gene Containment Development Genetics 100

Scienmag

JANUARY 18, 2022

The authors found that, whilst a low proportion of breastmilk contained COVID-19 genetic material, this did not translate into the presence of infectious replicating viral particles or lead to evidence of […].

Containment 58

Containment Genetics Research 58

XTalks

NOVEMBER 10, 2020

Expeditious and accurate diagnoses are necessary for patients to access healthcare services and treatment options for rare genetic diseases. Increasing the efficiency of case analysis and interpretation is essential to providing timely care for patients with genetic diseases.

Genome 98

Genome Genomics Medicine Genetic Disease 98

Camargo

DECEMBER 10, 2021

In October 2017, the European Commission (EC) and the European Medicines Agency (EMA) collaborated with the Member States’ authorities to launch a plan to reduce discrepancies across the EU in applying certain legislation to advanced therapy medicinal products (ATMPs) containing or consisting of genetically modified organisms (GMOs).

Development 176

Development Genetics Production Clinical Trials 176

Scienmag

JULY 14, 2021

Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles Credit: Mindy Takamiya/Kyoto University iCeMS Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The findings, by scientists at Kyoto […].

DNA 97

DNA Containment Scientist Research 97

Scienmag

JANUARY 8, 2021

Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers.

DNA 95

DNA Drug Delivery Containment Research 95

Pharmaceutical Technology

MAY 24, 2023

It can correct several disease elements associated with PKD, a rare, monogenic red blood cell disorder caused by a mutation in the PKLR gene.

Gene Therapy 130

Gene Therapy Gene Licensing Licensing 130

XTalks

JANUARY 21, 2025

The liquid portion of the blood (serum or plasma) containing antibodies is separated and tested using the Liason Biotrin parvovirus B19 IgG plus test on a Liason XL analyzer. There, plasma is separated, and tumor DNA is identified by detecting genetic mutations, methylation patterns and fragmentation signals.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

XTalks

JANUARY 14, 2021

Hahn, MD said, “The FDA will continue to monitor SARS-CoV-2 genetic viral variants to ensure authorized tests continue to provide accurate results for patients.”. The FDA says that while they may be impacted by new genetic variants of SARS-CoV-2, “the impact does not appear to be significant.”. In addition to B.1.1.7, 1.135 or 501.V2

Genetics 98

Genetics Genome Genomics Protein 98

Scienmag

JUNE 9, 2021

Credit: Kazan Federal University Homocysteine (HCY) is a sulfur-containing aminoacid, which attract more and more attention as the increase of homocysteine level associates with a number of pathological conditions. Hyperhomocysteinemia (hHCY) is an elevation of HCY level in plasma and develops due to genetic mutations of enzymes […].

Containment 52

Containment Genetics Development Research 52

pharmaphorum

OCTOBER 2, 2020

It uses a replication-deficient chimpanzee viral vector based on a weakened version of an adenovirus that that causes common cold infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. AZD1222 was co-invented by the University of Oxford and its spin-out company, Vaccitech.

Regulation 105

Regulation Vaccine Vaccination Protein 105

Scienmag

APRIL 8, 2021

This full assembly may contain clues to ape and human divergence; certain immune, brain and heart disorders; and other biomedical questions Credit: Kendra Hoekzema The full assembly of human chromosome 8 is reported this week in Nature.

Gene 90

Gene DNA Containment Genetics 90

FDA Law Blog

DECEMBER 8, 2022

labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., Other technical labeling matters.

Genetic Engineering 59

Genetic Engineering Containment Cosmetics Protein 59

XTalks

OCTOBER 21, 2020

The answer may lie in the genetic code of the virus, which scientists at Duke University have found contains several silent mutations that affect protein folding. So studying the genetics of the current coronavirus strain remains important. We’ll need to be able to recognize it and make efforts to contain it early.”.

RNA 98

RNA Protein Genome Genomics 98

XTalks

MARCH 21, 2024

The products contain ingredients like bamboo fiber, pea protein and mushrooms. The study also highlights how genetically engineered microorganisms can inhibit the growth of foodborne pathogens. Additionally, the offerings have the distinctive “snap” of the outer casing and the savory smokiness of Oscar Mayer products.

Genetic Engineering 98

Genetic Engineering Production Engineer Containment 98

The Pharma Data

OCTOBER 20, 2020

$1 million in research funding to support PD GENEration, a first-of-its-kind national study offering free genetic testing and counseling for people with Parkinson’s disease (PD). 10-15% of people with Parkinson’s disease have a genetic form of the disease. CAMBRIDGE, Mass.

Genetics 40

Genetics Clinical Trials Clinical Trials Gene 40

pharmaphorum

SEPTEMBER 9, 2020

Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate. He is currently the patient advocacy and engagement lead at Congenica, a digital health company that is investigating the genetic basis of rare diseases. For some people, a job is more than just a job.

Genome 103

Genome Genomics Genetics Genome Project 103