Scienmag

NOVEMBER 15, 2021

Cell biologists track this process by observing chromosomes—structures made of DNA that contain the genetic material of an organism. Cell division is an important process that underlies biological growth and repair. However, their analysis is still […].

DNA 83

DNA Containment Genetics Research 83

Pharmaceutical Technology

FEBRUARY 15, 2023

The active component of the Pfizer-BioNTech vaccine tozinameran, contains the genetic code for the coronavirus spike protein, inside a lipid (fat) capsule. The vaccine also contains other inactive ingredients such as cholesterol.

Vaccine 130

Vaccine Vaccination Containment Immune Response 130

Pharmaceutical Technology

MAY 24, 2023

The ability to modify or introduce genetic material in human cells in such a precise and patient-centered manner clearly constitutes a breakthrough in personalized medicine. CGT drugs fall into two major categories: autologous and allogeneic. This is a primary factor for the staggeringly high unit cost of CGT.

Clinical Trials 246

Clinical Trials Clinical Trials Gene Therapy Clinical Supply Chain 246

The Pharma Data

NOVEMBER 19, 2020

MD, FAAP, Cincinnati Children’s Hospital, who will discuss genetic forms of hearing loss in children. Dr. John Greinwald is a tenured professor of Otolaryngology and Pediatrics with over 20 years of experience with a focus on the genetic causes and treatment of deafness. To register for the call, please click here. Disclaimer.

Genetics 52

Genetics Containment Genetic Disease Gene 52

Scienmag

NOVEMBER 20, 2020

Scientists at Goethe University within the international consortium COVID19-NMR refine previous 2D models The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains the information for the production of 27 proteins.

Genome 70

Genome Genomics RNA Protein 70

Scienmag

MAY 7, 2021

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling […]. (..)

DNA 62

DNA Regulation Genome Genomics 62

Pharmaceutical Technology

SEPTEMBER 20, 2022

The production of commercial dose non-sterile products such as tablets, capsules, ointments, creams, and powders is rising due to their growing global demand, attributed to increasing demand for anti-ageing products, hereditary factors, genetic mutations, exposure to harmful radiation, and rising geriatric population.

Marketing 100

Marketing Drug Delivery Systems Production Containment 100

STAT News

OCTOBER 12, 2022

From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

DNA 144

DNA Containment Scientist Medicine 144

Scienmag

FEBRUARY 19, 2021

Undergraduate students explore a more efficient way to measure protein-containing vessels released by cells Credit: DGIST Despite our great progress in understanding various cellular mechanisms over the last decades, many of them remain unclear.

Containment 52

Containment RNA Protein Genetics 52

The Pharma Data

DECEMBER 28, 2020

About Fulgent Genetics. Fulgent Genetics’ proprietary technology platform has created a broad, flexible test menu and the ability to continually expand and improve its proprietary genetic reference library while maintaining accessible pricing, high accuracy and competitive turnaround times. TEMPLE CITY, Calif.,

Genetics 52

Genetics Sales Gene Sequencing Marketing 52

Scienmag

JANUARY 18, 2022

The authors found that, whilst a low proportion of breastmilk contained COVID-19 genetic material, this did not translate into the presence of infectious replicating viral particles or lead to evidence of […].

Containment 58

Containment Genetics Research 58

XTalks

NOVEMBER 10, 2020

Expeditious and accurate diagnoses are necessary for patients to access healthcare services and treatment options for rare genetic diseases. Increasing the efficiency of case analysis and interpretation is essential to providing timely care for patients with genetic diseases.

Genomics 98

Genomics Genome Medicine Genetic Disease 98

Camargo

DECEMBER 10, 2021

In October 2017, the European Commission (EC) and the European Medicines Agency (EMA) collaborated with the Member States’ authorities to launch a plan to reduce discrepancies across the EU in applying certain legislation to advanced therapy medicinal products (ATMPs) containing or consisting of genetically modified organisms (GMOs).

Development 176

Development Genetics Production Clinical Trials 176

Scienmag

JANUARY 8, 2021

Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers.

DNA 95

DNA Drug Delivery Containment Research 95

Pharmaceutical Technology

MAY 24, 2023

It can correct several disease elements associated with PKD, a rare, monogenic red blood cell disorder caused by a mutation in the PKLR gene.

Gene Therapy 130

Gene Therapy Gene Licensing Licensing 130

XTalks

JANUARY 21, 2025

The liquid portion of the blood (serum or plasma) containing antibodies is separated and tested using the Liason Biotrin parvovirus B19 IgG plus test on a Liason XL analyzer. There, plasma is separated, and tumor DNA is identified by detecting genetic mutations, methylation patterns and fragmentation signals.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

Scienmag

JUNE 9, 2021

Credit: Kazan Federal University Homocysteine (HCY) is a sulfur-containing aminoacid, which attract more and more attention as the increase of homocysteine level associates with a number of pathological conditions. Hyperhomocysteinemia (hHCY) is an elevation of HCY level in plasma and develops due to genetic mutations of enzymes […].

Containment 52

Containment Genetics Development Research 52

pharmaphorum

OCTOBER 2, 2020

It uses a replication-deficient chimpanzee viral vector based on a weakened version of an adenovirus that that causes common cold infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. AZD1222 was co-invented by the University of Oxford and its spin-out company, Vaccitech.

Regulation 105

Regulation Vaccine Vaccination Protein 105

Scienmag

APRIL 8, 2021

This full assembly may contain clues to ape and human divergence; certain immune, brain and heart disorders; and other biomedical questions Credit: Kendra Hoekzema The full assembly of human chromosome 8 is reported this week in Nature.

Gene 90

Gene DNA Containment Genetics 90

FDA Law Blog

DECEMBER 8, 2022

labeling of major food allergens in bulk foods, dietary supplements, protein-free ingredients, and foods produced through genetic engineering); and. Most notably, the draft guidance clarifies that the following food products are subject to the allergen labeling requirements: Bulk containers (e.g., Other technical labeling matters.

Genetic Engineering 59

Genetic Engineering Containment Cosmetics Protein 59

XTalks

MARCH 21, 2024

The products contain ingredients like bamboo fiber, pea protein and mushrooms. The study also highlights how genetically engineered microorganisms can inhibit the growth of foodborne pathogens. Additionally, the offerings have the distinctive “snap” of the outer casing and the savory smokiness of Oscar Mayer products.

Genetic Engineering 98

Genetic Engineering Production Engineer Containment 98

Pharma Tutor

MAY 4, 2020

In January 2020, a previously unknown new virus was identified subsequently named the 2019 novel corona virus, and samples obtained from cases and analysis of the virus’ genetics indicated that this was the cause of the outbreak. Isolation remains the most effective measure for containment of COVID-19.

Containment 64

Containment Genetics 64

Medical Xpress

MAY 9, 2023

Leucine-rich repeats containing 4 (LRRC4)—a gene abundantly found in the brain and located on human chromosome 7q31–32—plays a pivotal role in memory formation, autism, spinal cord injury, as well as in determining the malignant potential, development, and progression of glioblastoma (GB), an aggressive cancer involving the brain and/or spinal cord. (..)

Gene 77

Gene Containment Development Genetics 77

XTalks

AUGUST 10, 2021

Moreover, studies show that saliva samples can contain a marginally higher SARS-CoV-2 viral load compared with nasopharyngeal samples (shown in a study involving hospitalized patients), and that the virus can be detected in saliva for a greater number of days post-infection. A porous membrane was engineered to capture RNA on its surface.

RNA 105

RNA Containment DNA Engineer 105

pharmaphorum

SEPTEMBER 14, 2020

It uses a weakened, non-replicating, version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 coronavirus spike protein. AZD1222 was co-invented by the University of Oxford and its spin-out company, Vaccitech.

Vaccine 104

Vaccine Vaccination Trials Protein 104

Advarra

AUGUST 31, 2022

Tools or special sharp containers to remove the needle and replace with a fresh and already capped needle. All potentially infectious sharps must be disposed of in a biohazard sharps container immediately after use without recapping. The container can be a rigid plastic container (e.g., The one-handed scoop technique.

Production 52

Production Biohazard Biohazard Containment 52

pharmaphorum

MAY 4, 2022

There are existing alternatives, with one being human cell culture systems, which provide an environment that is closer to that which will eventually receive treatment but do not contain the complexity of a complete organism. Organ-on-a-chip.

Drugs 143

Drugs Licensing Licensing Pharma Companies 143

Scienmag

AUGUST 13, 2020

Researchers from the Garvan Institute of Medical Research have uncovered four new subtypes of cells within triple negative breast cancer, which contain promising new therapeutic targets for the aggressive disease.

Genome 74

Genome Genomics Containment Research 74

pharmaphorum

AUGUST 16, 2020

It is based on an adenoviral vector formed on a weakened version of the adenovirus that causes a common cold-line illness in chimpanzees, containing the genetic material of SARS-CoV-2 spike protein.

Vaccine 111

Vaccine Vaccination Immune Response Trials 111

Scienmag

JULY 13, 2021

Credit: OIST For the first time, scientists have seen stony coral cells engulf dinoflagellates – single-celled, photosynthetic algae that are crucial for keeping coral alive The researchers used a cell line called IVB5, which contains endoderm-like cells cultured […].

Containment 71

Containment Scientist Research Genetics 71

Scienmag

MAY 18, 2021

(Boston)–Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

Immune Response 41

Immune Response Reagent Research Protein 41

FDA Law Blog

SEPTEMBER 29, 2022

Plaintiffs challenged the use of the term bioengineered (rather than GMO or genetically engineered), the limitation of the mandatory disclosure being required only if the food contains detectable modified genetic material and the options of using a QR code disclosure or a text message for the disclosure statement.

Genetic Engineering 59

Genetic Engineering Containment Genetics Regulation 59

Advarra

OCTOBER 26, 2023

Controlled Environment and IP Containment The potential for a release, and the risk associated with a genetically engineered IP, are part of the IBC’s assessment purview under National Institutes of Health (NIH) Guidelines. The containment must then prevent spills or leaks if the IP is dropped. Size matters.

Production 52

Production Containment Biohazard Biohazard 52

Scienmag

SEPTEMBER 14, 2021

The term ‘DNA’ immediately calls to mind the double-stranded helix that contains all our genetic information. But the individual units of its two strands are pairs of molecules bonded with each other in a selective, complementary fashion.

DNA 40

DNA Gene Containment Genetics 40

XTalks

SEPTEMBER 15, 2020

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. Specifically, the vaccine contains human recombinant glutamate decarboxylase 65 (GAD65) protein conjugated to aluminum hydroxide (GAD-alum).

Vaccine 103

Vaccine Vaccination Insulin Trials 103

XTalks

MAY 15, 2023

Fabry disease, also known as Anderson-Fabry disease, is a rare genetic disorder that falls under the category of lysosomal storage diseases. Genetic confirmatory testing is then conducted to identify the specific mutations in the GLA gene. The administration of Elfabrio is performed by a healthcare professional.

FDA Approval 98

FDA Approval Gene Genetics Clinical Trials 98

XTalks

MARCH 22, 2024

According to the EWG, about 95 percent of nonorganic strawberries, certain leafy greens (including spinach, kale, collard and mustard greens), grapes, peaches and pears contain detectable levels of pesticides. Children and farmworkers are among the most vulnerable, and exposure can lead to genetic damage and impaired neurodevelopment.

Contamination 109

Contamination Regulation Containment Genetics 109