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Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

In the same space, a different team of Cambridge scientists used whole genome sequencing to map out the largest sample of mutational signatures yet. The team identified 58 entirely new signatures and developed a computer tool that can help oncologists spot these signatures in individual patients.

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As the Smithsonian wraps a landmark genome exhibit, leaders in the field reflect on what’s changed

STAT News

When the Smithsonian National Museum of Natural History opened its genomics exhibit in 2013, the field was just celebrating the 10th anniversary of the completed Human Genome Project. Sequencing that first genome cost over $500 million. The genomes since cost $10,000. Read the rest…

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A new dawn of the genomic age: five areas set to be transformed in 2023

pharmaphorum

In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA. With its already strong genomics foundation, the passing of this bill will cement the UK as a world leader in genomics.

Genomics 129
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Realising the promise of genomic testing across oncology

pharmaphorum

Unlocking the secrets of the human genome has long been an ambitious pursuit for researchers around the world. The post Realising the promise of genomic testing across oncology appeared first on.

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A history of blood cancer treatment

pharmaphorum

Similar to Newbury, McBean – known to be a highly respected tradesman – developed fatigue and severe pain from weak and easily broken bones. During this period, Nobel prize-winning German scientist Paul Ehrlich developed his lock-key hypothesis of molecules that specifically bind to cell receptors.

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The future of genomic medicine: can it fulfil its promises?

pharmaphorum

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. Now, however, the field is changing with respect to genomic medicine. However, there are still hurdles to overcome to understand completely how a patient’s genome impacts their health.

Genomics 119
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CRISPR therapies targeting the next breakthrough in oncology

pharmaphorum

The potential of CRISPR technology has been a hot topic in the industry ever since it was first developed, but as trials progress further into the clinic, what therapeutic areas could be set to benefit? What this means is that it can edit virtually any segment of DNA, whilst being more precise and cheaper than existing editing tools.