Remove Development Remove DNA Remove Genotype
article thumbnail

Why Proviral DNA Drug Resistance Testing is Useful in Guiding Treatment Decisions for HIV-1 Patients

XTalks

While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. HIV Drug Resistance Testing.

DNA 98
article thumbnail

Top 30 New Medical Devices of 2024

XTalks

TriClip G4 System Manufacturer/developer : Abbott Medical Date of FDA approval : April 1, 2024 Approved for : Tricuspid regurgitation (TR). Abbott Spinal Cord Stimulation (SCS) Systems Manufacturer/developer : Abbott Medical Date of FDA approval : May 30, 2024 Approved for : Chronic, hard-to-manage pain in the torso, arms and legs.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

The Role of Oncology Biomarkers in Personalizing Hematology Treatment Plans

Worldwide Clinical Trials

Hematological cancer cells can also develop resistance to therapies over time, reducing treatment effectiveness. These developments, combined with targeted therapies, have dramatically improved survival status and quality of life for those diagnosed with hematological cancers.

Genetics 195
article thumbnail

LabCorp Backs Resolution Bioscience’s Liquid Biopsy Test for NSCLC

XTalks

The test was developed by Resolution Bioscience and the company will run test analyses in its labs. The Resolution ctDx Lung assay was developed to offer patients and clinicians with pertinent information that can inform treatment decisions. Related: Liquid Biopsies Help Match Cancer Patients to Phase I Trials.

Gene 105
article thumbnail

Biorepositories as a Guiding Resource for Research & Drug Discovery

XTalks

Data generated through high-throughput omics approaches paired with clinical patient records can give rise to remarkably robust datasets to inform and guide disease insights and development of targeted therapeutics. Genomic biomarker discovery helps drive the development of innovative new personalized therapies. Biobanking Models.

article thumbnail

Osimertinib Resistance and EGFR Mutations in NSCLC Treatment

Bioengineer

Analysis of circulating tumor (ct) DNA at the time of treatment discontinuation or progression showed that 49% of patients in the AURA3 trial lacked the T790M mutation. Often, the loss of T790M is associated with the development of alternative competitive resistance mechanisms.

Genome 119
article thumbnail

8 Frequently Asked Questions About Genetic Testing in Clinical Trials

Worldwide Clinical Trials

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. Once a sample is received at Invitae, DNA is extracted and the requisitioned test is performed via next generation sequencing.