Remove Development Remove Drug Trials Remove Genetics
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How using AI in clinical trials accelerates drug development

Pharmaceutical Technology

Pharma R&D teams are solving this problem by leveraging the power of artificial intelligence (AI) in clinical trials to save time and money. Drug development is already a difficult endeavor, with the vast majority of R&D efforts failing to produce a market-worthy product.

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Fatty liver disease: With little early detection, more challenging drug development

pharmaphorum

When cirrhosis complications develop, some will be lucky enough to be listed for a transplant. Obesity, diabetes, and genetics are the primary drivers, and COVID is about to make this exponentially worse. Dozens of companies are working at various stages of drug development. Others are not so fortunate. About the Author.

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Diseases Don’t Discriminate, So Why Aren’t Clinical Trials More Diverse?

XTalks

A study published in JAMA Oncology found that in cancer drug trials conducted between 2008 and 2018, nearly two-thirds of participants were non-Hispanic whites. When trial populations don’t match the broader patient base, the treatments they produce aren’t as effective. Nearly all diseases have a genetic component.

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Clinical Trials for Pulmonary Fibrosis: How Can Participation Be Improved?

XTalks

The exact cause of pulmonary fibrosis is often unknown, and in such cases, it is referred to as idiopathic pulmonary fibrosis (IPF); however, certain factors can contribute to the development of pulmonary fibrosis, including environmental and occupational exposures, certain medications, autoimmune diseases and genetic predisposition.

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Building Inclusive Trials: Insights from CTTI’s Diversity Initiatives

XTalks

Historically, racial and ethnically minoritized groups or populations have been excluded from clinical trials, leading to a lack of data on how different demographic subgroups respond to treatments. It also develops trust in clinical trials results and facilitates uptake if a medical product is approved,” Mervin-Blake noted.

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Why Black People Remain Underrepresented in Clinical Trials

XTalks

They are also at a high risk of developing heart disease and stroke. times greater risk of developing kidney disease and are 2.3 times greater risk of developing kidney disease and are 2.3 They are also more likely to develop hypertension earlier in life than white individuals. In addition, Black individuals have a 5.6

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Can your LNP manufacturing platform cope with the pace of the mRNA revolution?

Pharmaceutical Technology

The successful development and deployment of the mRNA-based COVID-19 vaccines has catalysed the biopharma industry and paved the way to expand this drug modality to new therapeutic areas. Excluding vaccines, there are five mRNA therapeutic products in clinical trial development as of November 2022. billion by 2028.