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The Technical University of Denmark (DTU) has announced that an international scientific team has developed a CRISPR-based drug candidate that targets E coli directly and leaves the microbiome intact. The research team has designed four bacterial viruses which use CRISPR technology to kill the unwanted bacteria precisely.
ElevateBio has entered a partnership with Affini-T Therapeutics to progress the latter’s engineered TCR-T therapies focused on Kirsten rat sarcoma viral oncogene homolog (KRAS), a dominant oncogenic driver mutation in solid tumours. Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva.
Astellas Pharma and Sutro Biopharma have entered a global, strategic partnership and licencing agreement to discover and develop new immunostimulatory antibody-drug conjugates (iADCs). Astellas and Sutro will expedite the development of iADCs for three different biological targets. It can potentially enhance the anti-cancer effect.
Umoja Biopharma has signed a research agreement with IASO Biotherapeutics (IASO Bio) to develop off-the-shelf therapies for haematological malignancies. The post Umoja and IASO partner to develop therapies for haematological malignancies appeared first on Pharmaceutical Technology.
Capsida Biotherapeutics and Eli Lilly and Company ’s wholly owned subsidiary Prevail Therapeutics have announced a partnership for the development of non-invasive gene therapies for central nervous system (CNS) diseases.
BioMed X has entered a research partnership with Sanofi to leverage artificial intelligence (AI) for drug development. Under the joint research project, a new research team will be set up at the BioMed X Institute in Heidelberg, Germany. The companies will select a varied group of skilled researchers for the project.
Regeneron Pharmaceuticals has collaborated with Sonoma Biotherapeutics to discover, develop and commercialise new regulatory T cell (Treg) therapies for autoimmune diseases. The two companies will together research and develop T cell therapies for Crohn’s disease and ulcerative colitis, as well as two other undisclosed indications.
Researchers from Carnegie Mellon University and Allegheny Health Network have developed a new method for deep brain stimulation. The findings are published in the Journal of Neural Engineering. The findings are published in the Journal of Neural Engineering.
Studies reveal that people with Down syndrome (DS) have over a 90% lifetime risk of developing dementia caused by Alzheimer's disease (AD) as they age.
While several therapeutics are available for treating symptoms associated with epilepsy, researchers and patients have strongly called out the need for more holistic treatments that would address the condition as a whole. Meanwhile, others are researching the link between gene variation and different responses to treatments.
A civil engineeringresearcher at The University of Texas at Arlington will utilize a $122,000 grant to develop an automatic crack evaluation (ACE) system that could save time and money and prioritize maintenance for roads, bridges and runways.
Researchers at City of Hope in the US have developed a new potential therapy to treat glioblastoma multiforme (GBM), a kind of brain cancer. These viruses are engineered genetically for killing cancer. The post City of Hope researchersdevelop new brain cancer therapy appeared first on Pharmaceutical Technology.
University of Houston researchers have received $4.4 Department of Energy’s Advanced Research Projects Agency-Energy (ARPA-E) for two projects developed in the Cullen College of Engineering and Texas Center for Superconductivity at the University of Houston (TcSUH). million from the U.S.
In biopharma research and development, laboratory data now exist in petabytes. Now common on biotech job boards are positions like cloud engineer, data scientist, automation engineer, software engineer, machine learning engineer, and computational biologist. Continue to STAT+ to read the full story…
With the latest development, Sanofi will licence a NK cell engager programme that acts on B7H3 from the antibody-based NK cell engager therapeutics (ANKET) platform of Innate. On choosing the candidate, the company will oversee the complete development, production and marketing.
TFF Pharmaceuticals and the National Institute of Environmental Health Sciences (NIEHS) have signed an agreement for the development of dry powder formulations of high molecular weight hyaluronan (HMW-HA) for respiratory diseases.
Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.
A KAIST research team led by Ph.D. candidate Jae Hee Lee and Professor Keon Jae Lee from the Department of Materials Science and Engineering has developed a surface-lighting microLED patch for UV-induced melanogenesis inhibition. The team's research was published in Advanced Healthcare Materials.
Ginkgo Bioworks (Ginkgo) and the Wisconsin Alumni Research Foundation (WARF) have collaborated to discover next-generation GD2 CAR T-cell therapies to treat solid tumours. Ginkgo will partner with researchers from Wisconsin-Madison to discover new and improved GD2 CAR designs with improved persistence, fitness and proliferation.
Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Verily’s Immune Profiler platform is “a discovery engine consisting of proprietary immune profiling lab workflow, growing multi-omic database, and advanced analytical tools”.
The Indian Institute of Science (IISc) researchers from the Centre for Nano Science and Engineering (CeNSE) have developed fabricated pressure sensors that use paper as the medium which find applications in healthcare. This is because medical treatments depend considerably on accurate and precise measurement of pressure.
GentiBio and Bristol Myers Squibb (BMS) have signed a multi-year partnership agreement for developing new engineered Treg therapies for inflammatory bowel disease (IBD) patients. These therapies will be developed for re-instating immune tolerance and repairing tissue in IBD.
Scribe Therapeutics and Sanofi have signed a strategic partnership to expedite the development of breakthrough clustered regularly interspaced short palindromic repeats (CRISPR)-based cell therapies for cancer. Scribe is also entitled to receive potential payments worth over $1bn on meeting development and commercial milestones.
The Indian Institute of Science (IISc), Centre for BioSystems Science and Engineering, has designed a new method to deliver a vaccine candidate for tuberculosis (TB). The research involves using spherical vesicles secreted by bacteria coated on gold nanoparticles which can then be delivered to the immune cells.
Generate Biomedicines has signed a co-development and commercialisation agreement with the University of Texas MD Anderson Cancer Center to expedite the development of new protein therapeutics for oncology using generative AI. It enables innovative and collaborative research to rapidly bring new treatment options to patients.
Avista Therapeutics, a University of Pittsburgh Medical Center (UPMC) spinout, has entered a collaboration with Roche for developing new AAV gene therapy vectors for eyes. Roche will also make further payments to Avista during the collaboration’s research phase and clinical, sales-based milestone and royalty payments for resulting products.
Nimbus Therapeutics and Eli Lilly and Company (Lilly) have signed a research partnership and licence agreement to develop and market new therapies that activate a specific AMPK isoform to treat metabolic diseases. The company will lead the research activities, while Lilly will undertake the global development and marketing activities.
Atomwise and Sanofi have entered a strategic and exclusive research partnership to use the former’s artificial intelligence (AI)-driven AtomNet platform to discover and research up to five drug targets computationally. Furthermore, Sanofi will make tiered royalty payments on products that are developed under this partnership.
Just as a chef relies on quality ingredients for the perfect dish, marketers depend on cutting-edge research to craft campaigns that resonate with their audience. The Connection Between Pharma Research and Marketing Effective marketing starts with understanding your audience.
Researchers in the Oregon State University College of Engineering have harnessed the power of artificial intelligence to help protect bees from pesticides. Researchers in the Oregon State University College of Engineering have harnessed the power of artificial intelligence to help protect […]. CORVALLIS, Ore.
Innate Pharma has signed an exclusive licence agreement with Takeda to enable research and development of antibody drug conjugates (ADCs) against an undisclosed target, primarily focusing on coeliac disease. In addition, Innate will receive royalties on possible net sales of any commercial product to be developed under the licence.
The funds will support Maxion’s KnotBody platform to develop antibodies to treat autoimmune diseases. As per the company, this allows for a longer half-life in the body and gives the ability for further biomolecular engineering. As per Maxion, there are more than 80 types of autoimmune conditions.
Mekonos, a biotech platform developing cell therapies, has announced a new research collaboration with bit.bio, a synthetic biology company providing human cells for research, drug discovery and cell therapy.
Researchers at Massachusetts Institute of Technology (MIT) have designed the world’s first digital fabric fiber that contains digital devices which can sense, analyze and store health data, and use it to infer a person’s activity and state of health. This would generate exciting new possibilities for digital health applications.
A University of Minnesota Twin Cities research team has developed a new microfluidic chip for diagnosing diseases that uses a minimal number of components and can be powered wirelessly by a smartphone. The innovation opens the door for faster and more affordable at-home medical testing.
Merck and Synplogen have signed a non-binding Memorandum of Understanding (MoU) to expedite the development and manufacturing of viral vector-based gene therapy applications. The firms intend to merge their expertise to provide simplified viral vector gene therapy development, production and testing in Japan.
The Air Force Research Laboratory’s Minority Leaders Research Collaborative Program (ML-RCP) has awarded a two-year, $150,000 award to Ethan Ahn, an assistant professor of the UTSA Electrical and Computer Engineering Department.
An international team of scientists featuring Florida State University researchers has developed a model that predicts the spread of vortices in so-called superfluids, work that provides new insight into the physics that govern turbulence in quantum fluid systems such as superfluid neutron stars.
ElevateBio has raised $401m in a Series D financing round for advancing its technology platforms to expedite the design, production and development of cell and gene therapies. The technology platforms include the Life Edit gene editing platform, an RNA, cell, protein, vector engineering and induced pluripotent stem cells (iPSCs) platform.
The Icahn School of Medicine at Mount Sinai has launched a new research center devoted to understanding how epigenomics influences the nervous system under both healthy and disease conditions.
These stem cells are engineered to develop into dopamine-producing neurons, which are progressively lost in Parkinsons disease. This year has started strong for Parkinsons disease research with progress in several clinical trials and medical devices. As of 2023, there were approximately 2.7
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