pharmaphorum

MARCH 23, 2022

With initiatives like The 100,000 Genome Project, the UK has led the world on genomic research. Representatives from industry associations and the governments and NHS in all four UK nations will meet to discuss the future of the country’s genomics sector. Plans for a joint workshop.

Genome 72

Genome Genomics Genome Project Life Science 72

Drug Discovery World

NOVEMBER 7, 2022

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . Consequently, the UK has established itself at the forefront of diagnostic whole genome sequencing.

Genome 52

Genome Genomics Genetics Genetic Disease 52

Drug Discovery World

AUGUST 16, 2023

Therefore, it is now more critical than ever to advance the science to develop the next generation of RNA therapies, leveraging this molecule as a therapeutic modality with transformational potential. In actuality, the protein-coding portion of our genome is comparable in identity and number with the humble fruit fly or worm.

RNA 52

RNA Genome Genomics DNA 52

Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers. Genomic research have greatly expanded our understanding of disease pathophysiology over the years.

Genome Project 130

Genome Project Genome Genomics DNA 130

pharmaphorum

JANUARY 24, 2023

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

Genetics 82

Genetics Drugs Genome Project Biobanking 82

Drug Discovery World

SEPTEMBER 20, 2022

To develop safe and effective gene therapies, researchers need confidence that genomic data is both complete and accurate. This considerable magnitude of difference in read length affords researchers a more complete and accurate view of genomic variation.

Gene Therapy 52

Gene Therapy Gene Genome Genomics 52

Drug Discovery World

MARCH 13, 2024

Thanks to significant investment by the government into research and development, Singapore has become a leading centre for biomedical sciences in Asia. Following this, a medical innovation and development centre, Biopolis Hub, was opened in 2005. UK-based molecular diagnostics group Yourgene operates in Singapore.

Life Science 69

Life Science Genome Genomics Research 69

pharmaphorum

MARCH 25, 2021

The COSMIC (Catalogue of Somatic Mutations in Cancer) database, operated by the Wellcome Sanger Institute, grew out of the work of the Cancer Genome Project and has been gathering data on mutations associated with specific cancers for almost 17 years. The post COSMIC database matches drugs to cancer mutations appeared first on.

Drugs 59

Drugs Genome Project Genome Genomics 59

The Pharma Data

MARCH 1, 2022

The leading research-driven biopharmaceutical company Boehringer Ingelheim and precision medicine software company Lifebit Biotech, Ltd. This promises to unlock the transformational value of biomedical data by enabling seamless integration with world-leading population genomics and disease-focused cohorts.

Biobanking 52

Biobanking Genome Genomics Genome Project 52

Drug Discovery World

OCTOBER 16, 2023

Here, DDW’s Megan Thomas highlights the research taking place and where this is happening. This environment of research excellence, in turn, fosters R&D, innovation, spin-offs, start-ups, networking, collaboration and entrepreneurship, which sets a sturdy foundation that attracts funding, and creates an appealing work culture.

Drugs 75

Drugs Life Science Gene Therapy Genome 75

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 84

Genome Genomics Genetics Genome Project 84

pharmaphorum

FEBRUARY 25, 2021

The detail remains to be written,” he said, explaining that all four nations would now develop their own action plans for the implementation of the framework. “We In the future, Gourgeon went on, the data will help NHS Scotland to understand the impact of antenatal screening and to better support research.

Genome 85

Genome Genomics Genetics Medicine 85

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 65

Genome Genomics Genetics Genome Project 65

XTalks

APRIL 5, 2021

Bioinformaticians use a combination of mathematics, computer science and biology to help scientists make sense of the data gathered from research projects. The Human Genome Project could not have succeeded without the use of bioinformatics. This job furthers the field of biomedical research and supports drug development.

Bioinformatics 59

Bioinformatics Engineer Scientist Genome 59

Drug Discovery World

JULY 17, 2024

The findings, published in Nature , offer the first step in longed-for hope for the development of a treatment in the future. This discovery was initially made using data from the 100,000 Genomes Project, a study led by Genomics England and NHS England. The specific gene is called RNU4-2.

Genetics 52

Genetics Genome Project Genome Genomics 52

pharmaphorum

FEBRUARY 26, 2021

With only <10% of the affected people having treatment for their rare condition, the question remains – what impedes the process of developing a treatment for such diseases? The domain is marred with poorly-developed study endpoints and insufficient patient data. The brighter side – innovations in rare disease .

Drugs 55

Drugs Genome Project Genome Genomics 55

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. I saw this, in particular, with the finishing of the human genome,” says Charlie. “At In reality, finishing the human genome was the first step of what is a long journey.”.

Genome 107

Genome Genomics Medicine Gene 107

pharmaphorum

DECEMBER 6, 2022

Ben Hargreaves examines why a research project in the UK could provide key insights to develop treatments against many of the most prominent diseases impacting society. There are also hopes that clues could be found as to what risk factors are involved in the development of the most difficult to understand diseases.

Genome Project 87

Genome Project Research Genome Genomics 87

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. The tide has been turning in the worlds of diagnostics and drug development. A recent flurry of announcements indicates increasing interest and trust from major public health organisations in the power of genomics.

Genome 52

Genome Genomics Bioinformatics Genetics 52

Roots Analysis

AUGUST 28, 2022

The up-and-coming field of spatial genomics in biology promises to bridge the gap between high plex, high throughput, and high resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

Genome 52

Genome Genomics DNA Containment 52

pharmaphorum

SEPTEMBER 13, 2022

In fact, according to Blood Cancer UK research, more than half of UK adults cannot name a single symptom of blood cancer. . Over the past two centuries, researchers have identified more than 100 different types of blood cancer, while most patients may be familiar with the big three (leukaemia, lymphoma, and melanoma).

Genome Project 85

Genome Project Genome Genomics DNA 85

Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Nutrigenomics is the science studying the relationship between human genome, nutrition and health.

Genome 40

Genome Genomics Genetics Gene 40

Pharmaceutical Technology

SEPTEMBER 15, 2022

From the Human Genome Project to contemporary drug development, collaboration is critical to the life sciences. Take Charleston, South Carolina, for example, where a growing number of medical device and pharmaceutical manufacturers, research laboratories and service companies have sprung up or settled in recent years.

Life Science 130

Life Science Drug Delivery Genome Project Development 130

Drug Discovery World

MARCH 6, 2024

The development of effective new disease-modifying treatments in neurodegenerative and neuropsychiatric disorders has been hindered by their inherent genetic complexity, environmental influences, and clinical variability.

Genome 64

Genome Genomics Clinical Trials Clinical Trials 64

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

Genetics 119

Genetics DNA Genome Genomics 119

pharmaphorum

APRIL 20, 2022

The potential of CRISPR technology has been a hot topic in the industry ever since it was first developed, but as trials progress further into the clinic, what therapeutic areas could be set to benefit? As is typical, the research built on work going back years prior, specifically to 1987 when the first CRISPR mechanism was identified in E.

Gene Editing 52

Gene Editing DNA Gene Genetics 52

The Pharma Data

APRIL 6, 2021

Bayer will present new research across its oncology portfolio at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021 , taking place over two weeks on April 10-15 and May 17-21, 2021. The product is developed jointly by Bayer and Orion Corporation, a globally operating Finnish pharmaceutical company.

Research 52

Research Genome Project Gene Genome 52