Remove Development Remove Genome Project Remove Protein Remove RNA
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Junk DNA: How the dark genome is changing RNA therapies

Drug Discovery World

Samir Ounzain , PhD, CEO & Co-Founder of HAYA Therapeutics, looks at how a better understanding of our DNA can lead to increased activity for RNA therapeutics. The whole world realised the power of RNA when the Covid-19 pandemic brought us the first mRNA-based vaccines.

RNA 52
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A new dawn of the genomic age: five areas set to be transformed in 2023

pharmaphorum

The combination of advanced long- and short-read genomic sequencing technologies holds great promise for precision oncology, and in the development of mRNA vaccines for certain cancers. Just one mutation can lead to a complete change in protein formation. Just one mutation can lead to a complete change in protein formation.

Genome 125
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Researchers discover genetic cause of neurodevelopment disorders

Drug Discovery World

The findings, published in Nature , offer the first step in longed-for hope for the development of a treatment in the future. While nearly all genes known to be involved in NDD are responsible for making proteins, RNU4-2 is not; instead, it makes an RNA molecule that plays an important role in how other genes are processed in cells.

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Where is the drug discovery expertise happening in the UK?

Drug Discovery World

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases. billion in funding.

Drugs 75
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Spatial Genomics, Transcriptomics and Proteomics Solutions – An Amelioration of Tissue Analytics

Roots Analysis

Furthermore, several live cell imaging and non-destructive fluorescence histological methods measure limited number of biomarkers at a time and the tags introduced may interfere with the natural function of genes and proteins. 70+ spatial Genomics solutions are developed by industry and non-industry players. Concluding Remarks.

Genome 52
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Predictive diagnostics: closing the precision medicine gap

Drug Discovery World

In pursuit of this, the number of new therapeutics in development has boomed. New classes of therapies have added to this growth, including immune checkpoint inhibitors and genome targeted therapies. Both the binary and quantitative have relied on measurement of protein, DNA, and more recently, RNA.