Delveinsight

DECEMBER 13, 2020

Due to hepatitis C, most people develop cirrhosis, or scarring of the liver, before liver cancer; about 5–25% of patients with chronic hepatitis C develop cirrhosis over 10–20 years. Research and development in Hepatitis. In contrast, approximately 850,000–2.2 Hurdles in the Hepatitis treatment. Pegylated INF-?2b

Genotype 52

Genotype FDA Approval DNA Drugs 52

Advarra

FEBRUARY 28, 2023

In an effort to accelerate the sharing of biomedical research results, the National Institutes of Health (NIH) issued its finalized Data Management and Sharing (DMS) policy , effective January 25, 2023. The policy statement supported reusing existing scientific data and accessibility of high value datasets for use in future research studies.

Research 52

Research Genome Genomics Genotype 52

Drug Discovery World

NOVEMBER 23, 2023

Artificial Intelligence (AI) has become a popular buzzword in the drug discovery and development lexicon but not all approaches to AI-driven drug discovery produce meaningful insights that translate into real compounds which ultimately demonstrate clinical efficacy in human trials. But the utility of biobanks varies.

Biobanking 59

Biobanking Drugs Medicine Genome 59

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Generation of strong research dataset cohorts must begin with high-quality clinical samples. Partnerships and Establishing Research Cohorts.

Research 98

Research Biobanking Drugs Genome 98

pharmaphorum

NOVEMBER 10, 2021

“Better estimates of the burden of antimicrobial resistance in humans and animals depend on better microbiological data and more clarity on the appropriate design of epidemiological research. This database should support automatic importation from hospitals, laboratories and surveillance networks and link to genotypic data when available.”.

Medicine 94

Medicine Genome Genomics Genotype 94

XTalks

APRIL 29, 2021

While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. Proviral DNA Genotyping.

DNA 98

DNA Drugs RNA Genotype 98

XTalks

APRIL 15, 2021

New advances in heart failure genomics are helping to address this challenge. Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. Watch this on-demand webinar to hear from these experts.

Development 98

Development Drugs Genome Genomics 98

Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

Genome 52

Genome Genomics DNA Containment 52

XTalks

APRIL 24, 2023

“Rare disease clinical trials are complex due to the additional scientific, medical, operational and regulatory requirements of newly emerging advanced therapies, such as gene therapy,” says Dr. Terence Eagleton, MB BS, Senior Medical Director at the global clinical research organization (CRO) Medpace.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

Drug Discovery World

OCTOBER 30, 2023

RA: You’ve recently announced a collaboration with the University of Oxford to access genotype data on women with endometriosis. We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients.

Genome 72

Genome Genomics Genotype Clinical Trials 72

Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Nutrigenomics is the science studying the relationship between human genome, nutrition and health.

Genome 40

Genome Genomics Genetics Gene 40

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What is the difference between a Clinical Laboratory Improvement Amendments (CLIA)-approved laboratory vs a research laboratory?

Clinical Trials 130

Clinical Trials Clinical Trials Genetics Trials 130

Drug Discovery World

MAY 2, 2023

Some of the most important breakthroughs in pharmaceutical research were adapted from naturally occurring phenomena. In an effort to defend themselves against viral infection, bacterial cells capture and copy DNA fragments of bacteriophages into their genome. The gRNA is accompanied by the Cas9 enzyme responsible for cutting DNA.

Genome 52

Genome Genomics Gene DNA 52

Drug Discovery World

MAY 29, 2024

SpyBiotech and the University of Oxford Biotechnology company SpyBiotech and University of Oxford have entered a research agreement for the development of a vaccine against Epstein-Barr virus (EBV). ERS Genomics and IRBM ERS Genomics and IRBM have signed an agreement granting IRBM access to ERS’ CRISPR/Cas9 patent portfolio.

Drugs 52

Drugs Gene Editing Life Science Genome 52

Drug Discovery World

MARCH 1, 2023

Avtar Singh is a Senior Scientist in the Cell and Tissue Genomics Department at Genentech, where he develops new approaches for image-based screening and high-throughput biological discovery. SLAS2020 showed me how technology development fits into the landscape of drug discovery and stimulated me to further explore those possibilities.

Genetics 52

Genetics Genome Genomics Genotype 52

The Pharma Data

SEPTEMBER 2, 2021

in the US and Canada) to develop and commercialise Lynparza; with Daiichi Sankyo Company, Limited (Daiichi Sankyo) to develop and commercialise Enhertu and Dato-DXd, and with HUTCHMED to develop and commercialise savolitinib. AstraZeneca is collaborating with MSD (Merck & Co., Lead author. Abstract title. Garassino, MC.

Trials 52

Trials Medicine Antibody Clinical Trials 52

pharmaphorum

FEBRUARY 17, 2022

Researchers discovered a highly virulent variant of HIV in the Netherlands that genetic sequence analysis suggests has been circulating since the 1990s. . Identified as the “VB variant,” the virus has proved to be highly virulent and to speed up the progression of a patient developing AIDS faster. The VB variant.

Genome 89

Genome Genomics Genetics Genotype 89