BioTech 365

FEBRUARY 5, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: SSRgenotyper: A new tool to digitally genotype simple sequence repeats.SSRgenotyper is a newly developed, free bioinformatic tool that allows researchers to digitally genotype sequenced populations using simple … Continue (..)

Genotype 40

Genotype Bioinformatics Research Development 40

XTalks

APRIL 15, 2021

Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. The reverse could also be true whereby the development of coronary artery disease may impact heart rate. HFrEF vs. HFpEF.

Development 98

Development Drugs Genomics Genome 98

Worldwide Clinical Trials

AUGUST 14, 2024

Hematological cancer cells can also develop resistance to therapies over time, reducing treatment effectiveness. These developments, combined with targeted therapies, have dramatically improved survival status and quality of life for those diagnosed with hematological cancers.

Genetics 195

Genetics Protein Gene Genotype 195

Worldwide Clinical Trials

FEBRUARY 6, 2023

The best course of action will depend on many variables, such as the disease or population being studied and the genotype/phenotype relationship, risk, and impact on care. Obtaining appropriate assistance to facilitate planning up front for the complexities involved will save sponsors time and effort in the long run.

Genetics 130

Genetics Clinical Trials Clinical Trials Genotype 130

Scienmag

AUGUST 25, 2020

Credit: Iliana Baums, Penn State Coral conservation efforts could get a boost from a newly developed genotyping “chip”–the first of its kind for corals.

Genotype 66

Genotype Genetics Development Research 66

XTalks

JANUARY 21, 2025

TriClip G4 System Manufacturer/developer : Abbott Medical Date of FDA approval : April 1, 2024 Approved for : Tricuspid regurgitation (TR). Abbott Spinal Cord Stimulation (SCS) Systems Manufacturer/developer : Abbott Medical Date of FDA approval : May 30, 2024 Approved for : Chronic, hard-to-manage pain in the torso, arms and legs.

FDA Approval 105

FDA Approval Manufacturing Development RNA 105

Scienmag

JUNE 23, 2022

Orofacial clefts (OFCs) are congenital birth defects where the independently derived facial primordia that form the orofacial complex fail to fuse properly during embryonic development. 170 GWAS derived SNPs were genotyped on 3000 replication samples from participants in Ethiopia, Ghana, and […].

Genotype 58

Genotype Genomics Genome Development 58

pharmaphorum

JANUARY 18, 2023

Pharmaceutical companies and biotechs are also adapting their approaches, launching patient finding and engagement programmes that can start years before clinical trials begin and allow them to run ‘recontact by genotype’ studies that the Resilience Project would have liked to do. Giving participants something in return. About the author.

Genetic Disease 97

Genetic Disease Genetics Research Genomics 97

Scienmag

JANUARY 13, 2021

To discover these associations, researchers need to compare the genomes of many individuals at millions of genetic locations or markers, and therefore require cost-effective genotyping technologies. A new statistical method, developed […].

Genome 57

Genome Genomics Genotype Genetics 57

Pharmaceutical Technology

DECEMBER 15, 2022

Since HFC replacement therapy is the mainstay of treatment for CFD, increased development of more innovative fibrinogen-based therapies will benefit both the CFD population and patients experiencing AFD. CFD is an extremely rare disease in which many patients are often asymptomatic and do not require treatment.

Marketing 130

Marketing Production Genotype Development 130

pharmaphorum

JANUARY 21, 2022

The findings have been submitted to the Genotype-to-Phenotype National Virology Consortium (G2P-UK), the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) and the Joint Committee on Vaccination and Immunisation (JCVI).

Antibody 115

Antibody Vaccination Vaccine Genotype 115

Pharmaceutical Technology

JUNE 6, 2023

The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. Pharma Mar Overview Pharma Mar discovers, develops and markets marine-derived drugs to treat cancer. Its development pipeline includes PM14 for solid tumors, among others.

Hormones 100

Hormones In-Vitro Genotype Bacteria 100

BioTech 365

AUGUST 17, 2020

ETD002 is a novel TMEM16A chloride channel potentiator Therapy applicable to all cystic fibrosis patients, independent of genotype BRIGHTON, England–(BUSINESS WIRE)–Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives … Continue reading (..)

Genotype 40

Genotype Trials Development 40

Delveinsight

DECEMBER 13, 2020

Due to hepatitis C, most people develop cirrhosis, or scarring of the liver, before liver cancer; about 5–25% of patients with chronic hepatitis C develop cirrhosis over 10–20 years. Research and development in Hepatitis. 2b) was developed to maintain a steady level of an active drug and reduce the frequency of administration.

Genotype 52

Genotype FDA Approval DNA Drugs 52

XTalks

MARCH 29, 2021

Grantz, of the Division of Intramural Population Health Research at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development. The results did not differ based on fast or slow caffeine metabolism genotype. Related: Maternal Antibodies: How Allergies Can be Passed from Mothers to Children.

Genotype 98

Genotype Allergies Hormones Research 98

pharmaphorum

JANUARY 24, 2023

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

Genetics 98

Genetics Drugs Genome Project Biobanking 98

Bioengineer

JANUARY 16, 2024

Often, the loss of T790M is associated with the development of alternative competitive resistance mechanisms. Importantly, a triple mutant scenario with EGFR L858R/T790M/C797S or EGFRexon19del/T790M/C797S genotype may occur in patients with T790-positive NSCLC receiving osimertinib in second or later lines.

Genome 119

Genome Genomics Protein In-Vitro 119

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. It is important to consider the type of testing performed (e.g., single gene testing vs comprehensive panel), the reportable range (e.g.,

Clinical Trials 130

Clinical Trials Clinical Trials Genetics Trials 130

XTalks

APRIL 29, 2021

While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. Proviral DNA Genotyping.

DNA 98

DNA Drugs RNA Genotype 98

XTalks

JULY 10, 2024

” The Xpert HCV test’s development was validated through the Independent Test Assessment Program (ITAP), part of the National Institutes of Health’s (NIH) Rapid Acceleration of Diagnostics (RADx) Tech program. Without treatment, over half become chronically infected, with 10 to 20 percent developing cirrhosis over 20 to 30 years.

RNA 97

RNA In-Vitro Genotype Marketing 97

pharmaphorum

JANUARY 29, 2019

How the shift towards cancer as a phenotype/genotype is being applied in clinical trials and how they are run •What are co-clinical trials and why could they hold the key to answering unmet need in cancer treatment and beyond into broader drug development? What are the implications from these changes for clinical trials?

Genomics 52

Genomics Genome Medicine Clinical Trials 52

XTalks

SEPTEMBER 28, 2020

The test was developed by Resolution Bioscience and the company will run test analyses in its labs. The Resolution ctDx Lung assay was developed to offer patients and clinicians with pertinent information that can inform treatment decisions. Related: Liquid Biopsies Help Match Cancer Patients to Phase I Trials.

Gene 105

Gene DNA Life Science Genotype 105

pharmaphorum

NOVEMBER 10, 2021

This database should support automatic importation from hospitals, laboratories and surveillance networks and link to genotypic data when available.”. New agents: Development and accessibility. This information would support the design and implementation of stewardship programmes.”.

Medicine 105

Medicine Genome Genomics Genotype 105

The Pharma Data

NOVEMBER 18, 2020

18, 2020 — Genetic variants in some patients with inflammatory bowel disease (IBD) are associated with a significantly increased risk for developing thromboembolic disease (TED), according to a study published online Oct. WEDNESDAY, Nov. 21 in Gastroenterology. Takeo Naito, Ph.D.,

Genetics 52

Genetics Genotype Genome Genomics 52

pharmaphorum

AUGUST 11, 2022

First, members who opt-in to the program receive a saliva collection kit, which is analysed using newly developed pharmacogenomics technologies. With this promise beginning to be realised, it’s on drug makers to use genomic testing to steer their development process.

Genome 98

Genome Genomics Drugs Genetics 98

XTalks

SEPTEMBER 15, 2020

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. Diamyd Medical is a clinical-stage biopharmaceutical company that develops therapies for type 1 diabetes.

Vaccination 103

Vaccination Vaccine Insulin Trials 103

The Pharma Data

NOVEMBER 2, 2020

(NASDAQ:ADIL; ADILW) , a clinical-stage biopharmaceutical company focused on the development of treatments for addictions, today provided an update on its landmark ONWARD Phase 3 pivotal trial. Adial Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the development of treatments for addictions.

Trials 52

Trials Genotype Marketing Production 52

pharmaphorum

OCTOBER 9, 2020

Most experience some form of cognitive difficulty, and some develop psychosocial problems related to short stature and feelings of social isolation. The team hopes that this study’s scope will also shed light on the gene’s impact on the women who carry it in addition to an elaborative genotype-phenotype correlation.

Research 111

Research Genetics Genotype Nurses 111

XTalks

MARCH 3, 2021

BridgeBio is dedicated to developing therapies for genetic diseases with unmet needs. BridgeBio said in an announcement that the novel therapy was developed based on “BridgeBio’s commitment to developing a treatment for MoCD Type A in collaboration with the experts and families in the MoCD Type A community.”

FDA Approval 64

FDA Approval Genotype Clinical Trials Clinical Trials 64

The Pharma Data

SEPTEMBER 8, 2021

TIB Molbiol excels in ultra-rapid assay development for emerging infectious disease, strongly demonstrated during the COVID-19 pandemic. For example, in 2001 with anthrax and 2003 with SARS-CoV1, TIB Molbiol demonstrated their ability to develop PCR assays for the detection of new pathogens within days.

Genotype 52

Genotype Reagent Genetics Research 52

The Pharma Data

OCTOBER 9, 2021

Food and Drug Administration (FDA) Antimicrobial Drugs Advisory Committee (AMDAC) voted unanimously to recommend use of maribavir (TAK-620) for the treatment of refractory cytomegalovirus (CMV) infection and disease with genotypic resistance to ganciclovir, valganciclovir, foscarnet or cidofovir in transplant recipients. About maribavir.

Drugs 52

Drugs Genotype Bioavailability Medicine 52

The Pharma Data

MARCH 7, 2022

The IGA results in the equivalent genotype (genetic make-up) and short-hair coat trait seen in some conventionally bred cattle, known as a “slick” coat. This is the FDA’s first low-risk determination for enforcement discretion for an IGA in an animal for food use. “It The low-risk determination was provided to Acceligen.

Genome 52

Genome Genomics Production Marketing 52

XTalks

JANUARY 22, 2021

Taiwan-based health and biotech company MedFluid has developed a rapid automated bacterial identification screening tool that can also tailor antibiotic treatments to an infection. It identifies bacteria using both genotypic and phenotypic assessments within 1.5

Bacteria 52

Bacteria In-Vitro Genotype Marketing 52

XTalks

APRIL 3, 2024

This development, announced earlier this week, introduces a significant twist in the ongoing saga of the H5N1 virus , which has been affecting birds globally and in the US since early 2022. genotype in wild birds from November 2023. The detection of HPAI in dairy cows marks a concerning development for the US dairy industry.

Genotype 45

Genotype Contamination Bacteria Development 45

The Pharma Data

JANUARY 26, 2021

Eli Lilly’s bamlanivimab, a neutralizing antibody initially developed by AbCellera, was approved for emergency use authorization in November by the U.S. Vir and GSK were already partnered on the development of VIR-7831, a dual-action monoclonal antibody that is currently being assessed in multiple Phase III studies.

Antibody 52

Antibody Genotype Trials Nurses 52

The Pharma Data

DECEMBER 9, 2020

Liebisch , Vigil Neuroscience is developing a pipeline of precision-based therapies to combat both rare and common neurodegenerative diseases by restoring the vigilance of microglia. It will if the following five companies, which all launched this year with Series A financing, have anything to say about it. . Vigil Neuroscience.

Marketing 52

Marketing In-Vivo Protein In-Vitro 52

The Pharma Data

NOVEMBER 18, 2020

To coordinate the global effort to protect the long-term efficacy of HIV medicines, WHO, in collaboration with HIVResNet, a global HIV resistance network, developed an HIV drug resistance prevention and assessment strategy. WHO has developed survey methods to monitor pretreatment HIV drug resistance. governance and enabling mechanisms.

Drugs 52

Drugs Genotype Medicine Development 52