SSRgenotyper: A new tool to digitally genotype simple sequence repeats
Scienmag
FEBRUARY 4, 2021
SSRgenotyper: A simple sequence repeat genotyping application for whole-genome resequencing and reduced representational sequencing projects.
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Scienmag
FEBRUARY 4, 2021
SSRgenotyper: A simple sequence repeat genotyping application for whole-genome resequencing and reduced representational sequencing projects.
Medical Xpress
APRIL 3, 2023
Work by an international research team led by Yu Xu and Michael Inouye at the Department of Public Health and Primary Care, University of Cambridge, has resulted in a unique resource for predicting multi-omics data directly from genotypes. A Research Briefing on the study is published in the same journal issue.
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Pharmaceutical Technology
AUGUST 18, 2022
0 genotypes. After more than a decade of research and clinical development, and through the perseverance of clinicians, patients and their families, the approval of Zynteglo marks a watershed moment for the field of gene therapy.”. Findings showed that 89% of evaluable subjects attained transfusion independence (TI).
Medical Xpress
FEBRUARY 28, 2023
Using artificial intelligence (AI) methods, researchers led by Professor Dr. Alexander Schönhuth from Bielefeld University's Faculty of Technology have succeeded in recording and deciphering the genotype profiles of 3,000 ALS patients and thus learning more about the development of the disease.
pharmaphorum
JANUARY 18, 2023
Pharmaceutical companies and biotechs are also adapting their approaches, launching patient finding and engagement programmes that can start years before clinical trials begin and allow them to run ‘recontact by genotype’ studies that the Resilience Project would have liked to do. Why should research be any different?
BioTech 365
FEBRUARY 5, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: SSRgenotyper: A new tool to digitally genotype simple sequence repeats.SSRgenotyper is a newly developed, free bioinformatic tool that allows researchers to digitally genotype sequenced populations using simple … Continue (..)
Worldwide Clinical Trials
AUGUST 14, 2024
Hematological cancer cells can also develop resistance to therapies over time, reducing treatment effectiveness. Recent Advancements in Biomarker Research The latest advancements in biomarker research have further elevated the biomarker’s role in disease diagnosis, treatment, and monitoring.
XTalks
FEBRUARY 4, 2021
Data generated through high-throughput omics approaches paired with clinical patient records can give rise to remarkably robust datasets to inform and guide disease insights and development of targeted therapeutics. Generation of strong research dataset cohorts must begin with high-quality clinical samples.
Scienmag
JANUARY 13, 2021
To discover these associations, researchers need to compare the genomes of many individuals at millions of genetic locations or markers, and therefore require cost-effective genotyping technologies. A new statistical method, developed […].
pharmaphorum
OCTOBER 9, 2020
Most experience some form of cognitive difficulty, and some develop psychosocial problems related to short stature and feelings of social isolation. We are not aware of so many aspects of this disease because they have not been researched adequately,” she says. The physical impact of Aarskog is extremely wide ranging.
Worldwide Clinical Trials
FEBRUARY 6, 2023
The best course of action will depend on many variables, such as the disease or population being studied and the genotype/phenotype relationship, risk, and impact on care. Obtaining appropriate assistance to facilitate planning up front for the complexities involved will save sponsors time and effort in the long run. Read the full article!
XTalks
APRIL 15, 2021
Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. The reverse could also be true whereby the development of coronary artery disease may impact heart rate. HFrEF vs. HFpEF.
Scienmag
AUGUST 25, 2020
Credit: Iliana Baums, Penn State Coral conservation efforts could get a boost from a newly developed genotyping “chip”–the first of its kind for corals.
pharmaphorum
JANUARY 21, 2022
A third dose of vaccine has been shown to effectively neutralise the Omicron variant of covid-19, according to researchers. Research led by UCLH, UCL and the Francis Crick Institute found that the booster dose successfully stimulates antibody levels that neutralise Omicron. Details of the study were published in The Lancet this week.
XTalks
JANUARY 21, 2025
TriClip G4 System Manufacturer/developer : Abbott Medical Date of FDA approval : April 1, 2024 Approved for : Tricuspid regurgitation (TR). Abbott Spinal Cord Stimulation (SCS) Systems Manufacturer/developer : Abbott Medical Date of FDA approval : May 30, 2024 Approved for : Chronic, hard-to-manage pain in the torso, arms and legs.
Pharmaceutical Technology
DECEMBER 15, 2022
Since HFC replacement therapy is the mainstay of treatment for CFD, increased development of more innovative fibrinogen-based therapies will benefit both the CFD population and patients experiencing AFD. CFD is an extremely rare disease in which many patients are often asymptomatic and do not require treatment.
Worldwide Clinical Trials
DECEMBER 12, 2022
Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What is the difference between a Clinical Laboratory Improvement Amendments (CLIA)-approved laboratory vs a research laboratory?
XTalks
MARCH 29, 2021
According to a study by researchers at the National Institutes of Health (NIH), moderate caffeine intake could lead to small babies. The research found that even consumption of less than the recommended moderate amount of 200 mg of caffeine per day for adults, which is about two cups of coffee, posed an increased risk to the fetus.
pharmaphorum
JANUARY 24, 2023
Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.
Delveinsight
DECEMBER 13, 2020
Due to hepatitis C, most people develop cirrhosis, or scarring of the liver, before liver cancer; about 5–25% of patients with chronic hepatitis C develop cirrhosis over 10–20 years. Research and development in Hepatitis. In contrast, approximately 850,000–2.2 Hurdles in the Hepatitis treatment. Pegylated INF-?2b
pharmaphorum
NOVEMBER 10, 2021
“Better estimates of the burden of antimicrobial resistance in humans and animals depend on better microbiological data and more clarity on the appropriate design of epidemiological research. This database should support automatic importation from hospitals, laboratories and surveillance networks and link to genotypic data when available.”.
XTalks
SEPTEMBER 28, 2020
The test was developed by Resolution Bioscience and the company will run test analyses in its labs. The Resolution ctDx Lung assay was developed to offer patients and clinicians with pertinent information that can inform treatment decisions. Related: Liquid Biopsies Help Match Cancer Patients to Phase I Trials.
XTalks
APRIL 29, 2021
While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. Proviral DNA Genotyping.
The Pharma Data
NOVEMBER 18, 2020
18, 2020 — Genetic variants in some patients with inflammatory bowel disease (IBD) are associated with a significantly increased risk for developing thromboembolic disease (TED), according to a study published online Oct. The researchers found that 122 of 792 IBD patients (15.4 WEDNESDAY, Nov. 21 in Gastroenterology.
The Pharma Data
SEPTEMBER 8, 2021
TIB Molbiol excels in ultra-rapid assay development for emerging infectious disease, strongly demonstrated during the COVID-19 pandemic. The acquisition enables Roche to further expand the portfolio of currently over 45 CE-IVD assays and more than 100 research use assays on Roche`s LightCycler PCR instruments. About TIB Molbiol.
The Pharma Data
NOVEMBER 2, 2020
(NASDAQ:ADIL; ADILW) , a clinical-stage biopharmaceutical company focused on the development of treatments for addictions, today provided an update on its landmark ONWARD Phase 3 pivotal trial. Adial Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the development of treatments for addictions.
XTalks
MARCH 3, 2021
BridgeBio is dedicated to developing therapies for genetic diseases with unmet needs. BridgeBio said in an announcement that the novel therapy was developed based on “BridgeBio’s commitment to developing a treatment for MoCD Type A in collaboration with the experts and families in the MoCD Type A community.”
Advarra
FEBRUARY 28, 2023
In an effort to accelerate the sharing of biomedical research results, the National Institutes of Health (NIH) issued its finalized Data Management and Sharing (DMS) policy , effective January 25, 2023. The policy statement supported reusing existing scientific data and accessibility of high value datasets for use in future research studies.
The Pharma Data
MARCH 16, 2022
Roche and its subsidiary, Tib Molbiol, confirm that it has tests for research use that identify the SARS-CoV-2 subvariants of concern, Omicron: BA.1, It’s critical to quickly and accurately identify variants to inform ongoing research – including the ongoing development of therapeutics and vaccines.
The Pharma Data
NOVEMBER 10, 2020
Biomarkers will be critical to developing precision medicine for Alzheimer’s disease. Although a few are out there, phosphorylated tau (P-tau) may enable even earlier and more accurate detection, according to Eli Lilly-associated researchers speaking at the Clinical Trials on Alzheimer’s Disease (CTAD) virtual conference in early November.
XTalks
JANUARY 22, 2021
Taiwan-based health and biotech company MedFluid has developed a rapid automated bacterial identification screening tool that can also tailor antibiotic treatments to an infection. It identifies bacteria using both genotypic and phenotypic assessments within 1.5
The Pharma Data
DECEMBER 9, 2020
Uniquely positioned in the rapidly evolving local biotech ecosystem in China in addition to an expansive global presence, Overland will strategically partner to jointly develop innovative, novel therapeutics. We look forward to developing and advancing our differentiated pipeline of novel therapeutics in carefully selected disease areas.”.
Roots Analysis
APRIL 28, 2024
However, the rising incidence and prevalence of rare kidney disease, with poor outcomes and high cost has led to an increased research activity in this domain. Such obstacles lead to the limited use of such mouse models for development of rare kidney disease drug.
Delveinsight
AUGUST 25, 2021
The pharmaceutical industry finds, develops, manufactures, and promotes medicines or pharmaceutical drugs for usage as medications that are administered (or self-administered) to patients in order to cure, vaccinate, or relieve symptoms. billion in research and development. The global healthcare spending in 2020 was USD 8.3
The Pharma Data
JANUARY 26, 2021
Eli Lilly’s bamlanivimab, a neutralizing antibody initially developed by AbCellera, was approved for emergency use authorization in November by the U.S. Vir and GSK were already partnered on the development of VIR-7831, a dual-action monoclonal antibody that is currently being assessed in multiple Phase III studies.
The Pharma Data
DECEMBER 9, 2020
Liebisch , Vigil Neuroscience is developing a pipeline of precision-based therapies to combat both rare and common neurodegenerative diseases by restoring the vigilance of microglia. It will if the following five companies, which all launched this year with Series A financing, have anything to say about it. . Vigil Neuroscience.
The Pharma Data
NOVEMBER 18, 2020
To coordinate the global effort to protect the long-term efficacy of HIV medicines, WHO, in collaboration with HIVResNet, a global HIV resistance network, developed an HIV drug resistance prevention and assessment strategy. WHO has developed survey methods to monitor pretreatment HIV drug resistance. governance and enabling mechanisms.
XTalks
APRIL 24, 2023
“Rare disease clinical trials are complex due to the additional scientific, medical, operational and regulatory requirements of newly emerging advanced therapies, such as gene therapy,” says Dr. Terence Eagleton, MB BS, Senior Medical Director at the global clinical research organization (CRO) Medpace.
Roots Analysis
AUGUST 12, 2024
Such test can be used for gene expression profiling, genotyping and detecting chromosomal abnormalities. These tests can identify biomarkers, genetic markers, and other molecular indicators that are associated with the development and progression of neurological diseases.
XTalks
DECEMBER 12, 2023
The world of neuroscience trials is rapidly evolving, presenting new challenges and opportunities for researchers and clinicians. This growth is primarily being driven by a rise in neurological diseases like stroke, dementia and peripheral neuropathy, coupled with increased R&D funding for neurological research. billion in 2022.
XTalks
MARCH 1, 2024
The Role of International HPV Awareness Day 2024 International HPV Awareness Day is important for industry professionals and the public to engage in open discussions, share the latest research and developments and commit to actionable steps towards preventing HPV-related diseases.
The Pharma Data
APRIL 7, 2021
“Women with triple-negative breast cancer have historically had very few effective treatment options and faced a poor prognosis,” said Aditya Bardia, MD, MPH, Director of Breast Cancer Research Program, Mass General Cancer Center and Assistant Professor of Medicine at Harvard Medical School, and global principal investigator of the ASCENT study.
Roots Analysis
SEPTEMBER 20, 2023
These compounds show an anti-plasmodial activity which is amongst the prime focus areas for researchers. Cannabis testing is also done to identify the plant genotype used to develop the product, providing transparency to the consumers.
Roots Analysis
AUGUST 31, 2023
Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. In addition, there is extensive research activity in the field of nutrigenomics, as researchers and industry players aim to enhance their existing offerings.
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