XTalks

DECEMBER 18, 2024

CAH is a group of rare genetic disorders affecting the adrenal glands, which produce essential hormones like cortisol, aldosterone and androgens. The most common form of CAH, 21-hydroxylase deficiency, disrupts hormone production, leading to cortisol deficiency and an overproduction of androgens.

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Genetics Hormones Trials Drugs 116

Scienmag

FEBRUARY 8, 2022

The human body responds to stress, from the everyday to the extreme, by producing a hormone called cortisol. Credit: Yichao Zhao and Zhaoqing Wang/UCLA The human body responds to stress, from the everyday to the extreme, by producing a hormone called cortisol.

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Hormones Development 80

Bio Pharma Dive

MAY 29, 2024

The Series B funding from Two Sigma Ventures, RA Capital and others will help Gameto develop technology it says could replace hormonal injections and shorten the IVF process.

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Hormones Development 183

Medical Xpress

NOVEMBER 15, 2022

Reproductive health experts consider hormonal contraceptives good choices for adolescents because they're safe and highly effective at preventing pregnancy, but one aspect of their effect on the teenage body remains a mystery—whether and how they modify the developing brain.

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Hormones Development 98

BioSpace

JANUARY 3, 2021

Pfizer and OPKO Health are one step closer to receiving approval for their jointly developed pediatric growth hormone deficiency drug, somatrogon, after the U.S. FDA recently accepted the companies’ regulatory submission for the therapy.

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Hormones Drugs Development 99

Medical Xpress

JANUARY 25, 2023

Prenatal exposure to altered levels of vitamin D and/or thyroid hormones has the potential to impact child development long after birth, according to a new study by researchers at the Marshall University Joan C. Edwards School of Medicine.

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Hormones Development Medicine Research 75

Camargo

NOVEMBER 29, 2021

The development of biological products (or biologics) represents a major advancement in modern medicine, enabling the treatment of patients with many illnesses where no other therapeutics were previously available. Biologics include a wide range of products , including: Vaccines. Blood and blood components. Allergenics. Somatic cells.

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Development Protein Production Hormones 180

STAT News

AUGUST 8, 2022

Aldosterone, a hormone produced by the triangular adrenal glands, might be the key target.    In the observational study, researchers analyzed health data from 3,680 people with chronic kidney disease for nearly 10 years. Read the rest…

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Hormones Research Development Drugs 98

Scienmag

APRIL 26, 2021

Credit: VCU Massey Cancer Center The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy.

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Hormones Drugs Production Development 92

Pharma Times

MAY 26, 2023

Therapy has been developed for use among children and adolescents with growth hormone deficiency

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Hormones Development 142

Scienmag

APRIL 22, 2021

These results can be used in the development of new cancer treatments, especially for hormone-dependent breast cancer. Researchers in Turku, Finland, have now demonstrated that the activities of distinct Notch family members are modified differently by phosphorylation. Breast cancer is […].

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Hormones Regulation Research Protein 75

Medical Xpress

MARCH 1, 2023

Controversies surrounding hormone therapy (HT) and its benefits and risks have dominated the women's health field for more than 2 decades. A large new study demonstrates that, despite some commonly held misperceptions, HT doesn't increase a woman's risk of developing lung cancer, and it could actually help reduce the risk.

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Hormones Development 74

Medical Xpress

APRIL 3, 2023

Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD. A new study, led by Mass General Brigham researchers, sheds light on the relationship between the risk of Alzheimer's disease and age of menopause and use of hormone therapy (HT).

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Hormones Development Research 80

Pharmaceutical Technology

FEBRUARY 24, 2023

(LAI-287 + semaglutide) is under clinical development by Novo Nordisk and currently in Phase III for Type 2 Diabetes. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data.

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Insulin Hormones Drugs Clinical Trials 182

Pharmaceutical Technology

AUGUST 8, 2022

The US Food and Drug Administration (FDA) has granted approval for a supplemental New Drug Application (sNDA) of Orion and its partner Bayer ’s Nubeqa (darolutamide) plus docetaxel to treat metastatic hormone-sensitive prostate cancer (mHSPC) patients.

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Hormones Clinical Trials Clinical Trials Licensing 246

Scienmag

APRIL 13, 2021

Skoltech researchers have developed a prototype of a fluorescence-based sensor for continuous detection of cortisol concentrations in real time, which can help monitor various health conditions. The paper was published in the journal Talanta.

Hormones 59

Hormones Regulation Development Research 59

Scienmag

OCTOBER 21, 2020

Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby’s brain development, a large American study shows. These chemicals, or hormones, are produced in the thyroid gland in the neck and are known to influence fetal growth.

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Hormones Regulation Production Development 66

Pharmaceutical Technology

JUNE 13, 2023

The combination therapy is intended to treat hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer in adult patients, after recurrence or progression on or after an endocrine-based regimen. AstraZeneca stated that its NDA is being reviewed under Project Orbis.

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HR Hormones Trials Protein 245

Medical Xpress

APRIL 26, 2023

A team of researchers at NYU Abu Dhabi (NYUAD), led by Khalil Ramadi, assistant professor of bioengineering at NYU Tandon and the Director of the Laboratory for Advanced Neuroengineering and Translational Medicine at NYU Abu Dhabi, has developed a first-of-its-kind ingestible electroceutical device for the neuromodulation of the gut-brain axis, the (..)

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Hormones Development Research Medicine 75

pharmaphorum

DECEMBER 1, 2021

Current treatments are dominated by generic drugs, and include topical antiseptics, retinoids which work by removing dead skin cells from the surface of the skin but can cause pain and inflammation, and topical antibiotics, as well as hormonal therapies including oral androgen inhibitors like spironolactone or cyproterone.

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Vaccine Vaccination Development Hormones 105

Pharmaceutical Technology

AUGUST 8, 2022

According to the trial data, Enhertu lowered disease progression or mortality risk by 50% compared with chemotherapy according to the physician’s choice in HER2-low metastatic breast cancer patients with hormone receptor (HR)-positive disease or HR-negative disease. months compared with 5.1 months for the chemotherapy arm.

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FDA Approval HR Clinical Trials Clinical Trials 264

XTalks

MARCH 19, 2025

Eneboparatide (AZP-3601), an investigational parathyroid hormone 1 receptor (PTH1R) agonist, met its primary endpoint in the CALYPSO Phase III trial, offering new data for adults with chronic hypoparathyroidism. AstraZeneca received eneboparatide during its $1.05 Without proper PTH function, patients may face kidney and bone complications.

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Trials Hormones Engineer Licensing 59

Scienmag

DECEMBER 15, 2021

Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world’s largest database of twins.

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Hormones Genetics Development Research 55

XTalks

MARCH 17, 2025

Roche, a global leader in biotechnology and diagnostics, has entered into an exclusive collaboration and licensing agreement with Zealand Pharma, a specialist in innovative therapeutics, to co-develop and co-commercialize petrelintide as a potential foundational therapy for people with overweight and obesity. billion $1.4

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Hormones Drugs Sales Insulin 59

Pharmaceutical Technology

FEBRUARY 9, 2023

Ibutamoren mesylate is under clinical development by Lumos Pharma and currently in Phase I for Turner Syndrome. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. It is administered orally.

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Hormones Clinical Trials Clinical Trials Drugs 100

XTalks

FEBRUARY 5, 2025

a clinical-stage biotech company focused on developing next-gen injectable and oral nutrient-stimulated hormone (NuSH) analog peptides for the treatment of obesity, overweight and related conditions, has priced its initial public offering (IPO) at $18.00 Despite this, the drug remains under watch for further development.

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Hormones Bioavailability Clinical Trials Clinical Trials 59

XTalks

SEPTEMBER 6, 2024

Novartis said the new facilities represent the company’s continued investment in developing a robust infrastructure to support the expanding use of radioligand therapies to treat cancer.

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Development Manufacturing Marketing Hormones 105

XTalks

JANUARY 23, 2024

Among these, rare pediatric diseases present unique challenges and opportunities for rare disease drug development. Pediatric growth hormone deficiency (PGHD) is one such condition, affecting a child’s growth and development.

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Development Hormones Drugs Trials 72

Scienmag

APRIL 6, 2021

Research provides insight into mechanistic factors that alter hepatic drug disposition during pregnancy Credit: BioIVT BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced that it will be hosting a webinar on April 8 at 11 a.m.

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Hormones Research Drugs Development 53

STAT News

FEBRUARY 8, 2023

Anderson will take over April 1, becoming the first American to run the 160-year-old conglomerate, which invented aspirin and later played a major role in the development of hormonal contraceptives, hemophilia clotting factors, and the blood thinner Xarelto. He will become chairman on June 1.

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Hormones Development 122

Medical Xpress

MAY 15, 2023

Women who experience more severe hot flashes after menopause are more likely to develop metabolic syndrome and high blood pressure, according to research presented at the 25th European Congress of Endocrinology in Istanbul.

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Hormones Development Research Gerontology 104

XTalks

AUGUST 30, 2024

Aphaia Pharma is developing innovative, non-hormonal treatments for metabolic conditions like diabetes and obesity. Bolz holds a full professorship at the University of Toronto, is a Principal Investigator at the Ted Rogers Centre for Heart Research and Director of the Toronto Centre for Microvascular Medicine.

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Hormones Life Science Scientist Medicine 52

pharmaphorum

MAY 20, 2021

NICE has rejected Johnson & Johnson’s oral prostate cancer drug Erleada (apalutamide) in patients with hormone-relapsed or hormone sensitive disease in first draft guidance. Hormone relapsed disease has stopped responding to hormone therapy and is usually treated with ADT alone or with Bayer’s Nubeqa (darolutamide) and ADT.

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Hormones Drugs Trials Manufacturing 98

Medical Xpress

APRIL 27, 2023

Neuroendocrine neoplasms (NENs) are rare cancers that develop from specialized secretory cells of the neuroendocrine system. These cells are found throughout the body and exhibit features of the nervous and endocrine/hormonal systems.

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Hormones Development 98

XTalks

FEBRUARY 21, 2025

Related: Obesity-Focused Metsera Launches IPO Amid Much Anticipation Aardvarks approach centers on developing novel, small-molecule drugs that harness the bodys natural hunger-regulating mechanisms. In the gut, these receptors prompt the release of hormones such as cholecystokinin and GLP-1, which together signal satiety.

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Genetics Hormones Gene Expression Gene 59

XTalks

NOVEMBER 6, 2024

Companies like Mallinckrodt, with its SelfJect injector for chronic and autoimmune conditions, and Evofem Biosciences, with its hormone-free Phexxi contraceptive gel , are developing solutions that simplify and improve medication use for patients with specific needs.

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Drug Delivery Drugs Bioequivalency Bioavailability 104

Outsourcing Pharma

MAY 17, 2024

Bayer announced today (May 17) that it will showcase its results of two phase 3 studies that could combat hot flushes for menopausal women.

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Hormones Clinical Development Development 76