Remove Development Remove Immune Response Remove In-Vivo Remove Vaccination
article thumbnail

LNP formulations produce strong immune responses, data shows 

Drug Discovery World

The strengths of etherna’s lipid based nanoparticle (LNP) platform have been showcased in a peer-reviewed paper in Advanced Functional Materials. etherna’s Vice President, Technology & Innovation, Stefaan De Koker described the paper as a “landmark” for the company and its technology.

article thumbnail

CohBar and Morphogenesis in merger for immuno-oncology therapies

Pharmaceutical Technology

Our board and management team believe that the combined company will be well-positioned to develop powerful new therapies with the potential to overcome resistance to current immunotherapies, an area of significant unmet need.” IFx has been designed to activate an innate immune response against tumour antigens that are patient-specific.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

T-cell vaccine for COVID-19 may last longer than current vaccines

The Pharma Data

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time. of the mice that were vaccinated with the T-cell-based vaccine survived, while only one of the control-group mice survived.

article thumbnail

New antiviral offers potential solution to resistant Covid-19 variants

Drug Discovery World

Infex Therapeutics has selected the clinical candidate for its in-house COV-X programme based on this in vivo efficacy data in a murine SARS-CoV-2 model. COV-X targets the key coronavirus PLpro enzyme, which is essential for viral replication and evasion of host immune response.

In-Vivo 52
article thumbnail

ImmunityBio’s hAd5 T-Cell COVID-19 Vaccine Candidate Shows Complete Protection of Airways in Non-Human Primates

The Pharma Data

.–( BUSINESS WIRE )– ImmunityBio , a privately-held immunotherapy company, today announced its COVID-19 vaccine candidate protected nasal and lung airways of non-human primates against coronavirus (SARS-CoV-2) in a challenge study. Graphic: Business Wire).

article thumbnail

Spotlighting Lupus Awareness Month: CAR-T Technology Creates New Avenues for Treatment of a Devastating Disease

WCG Clinical

Today there are six CAR-T products with FDA approval for the treatment of multiple myeloma and B cell malignancies, with many related and next-generation products under development. Lymphocytes have an extraordinary capacity to proliferate in response to immune stimulation.

In-Vivo 52
article thumbnail

Taking an ‘upside-down’ approach to mRNA delivery

pharmaphorum

Research into mRNA dates back to the 1970s, but with the approval of both Moderna and BioNTech/Pfizer’s vaccines, this approach has finally been validated. Once its potential as a means of stimulating an immune response had been established, attention quickly turned to where else the technology could provide a therapeutic solution.