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Recurrent brain trauma may increase Alzheimer's risk

Medical Xpress

New research finds that the brains of otherwise healthy military personnel who are exposed to explosions show an abnormal brain accumulation of amyloid-beta protein—a protein that plays a role in the development of Alzheimer's disease. The results of the study were published today in Radiology.

Radiology 106
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Symbiotica and Quidel Score FDA Authorizations for COVID-19 Tests

XTalks

COVID-19 antibody tests can help identify people who may have had prior COVID-19 infection, and importantly, asymptomatic individuals with a developing or current infection. The tests do not detect the SARS-CoV-2 virus itself, and hence should not be used for diagnostic purposes.

Antibody 102
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3 Newest COVID-19 Tests Authorized by the FDA

XTalks

Along with COVID-19 vaccine authorizations, the US Food and Drug Administration (FDA) remains committed to increasing access to COVID-19 tests and supporting their development, having authorized three new tests recently for emergency use. The products encompass molecular, antigen and T cell-based testing approaches.

Protein 98
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Novartis builds radio-oncology pipeline with iTheranostics deal

pharmaphorum

The diagnostic imaging agents all target fibroblast activation protein (FAP), a molecule that is only expressed at low levels on healthy cells but is found much more abundantly in solid tumours. Novartis licenses the drug from Genmab and reformulated into its Sensoready autoinjector pen.

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AZD1222 US Phase III primary analysis confirms safety and efficacy

The Pharma Data

It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The Phase III D8110C00001 trial is part of this funding agreement. Source link:[link].

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AstraZeneca’s COVID-19 vaccine; Type 1 diabetes research updates; FDA nod to Zebra’s X-ray modelling AI; UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3

Delveinsight

Warding off Type 1 diabetes by aiming a T-cell protein. Scientists at the University of Utah School of Medicine have found a way to control that autoimmune response by aiming a protein that is vital for T-cell activation. The protein is known as OCA-B. Zebra Medical Vision’s X-ray modelling AI gets the FDA clearance.

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AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis

The Pharma Data

It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The Phase III D8110C00001 trial is part of this funding agreement. Source link:[link].

Trials 52