Bio Pharma Dive

FEBRUARY 14, 2023

Formed by the Yale scientist and Arvinas founder, Halda Therapeutics is developing a twist on targeted protein degradation, an area of research that’s recently caught drugmakers’ attention.

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XTalks

APRIL 26, 2022

California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. So, how does the company make alt protein out of thin air? After that, in a process like beer fermentation, the protein is turned into a flour-like substance.

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Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Victoza, Copaxone, Lupron, Zoladex, Sandostatin, and Somatuline are some of the popularly marketed peptide API therapeutic drugs while more than 600 peptide-based pharmacological leads are being investigated worldwide, across various phases of development.

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Pharmaceutical Technology

DECEMBER 7, 2022

This collaboration will be validated through the consortium, Biologics Pharma Innovation Programme Singapore (BioPIPS), initiated by A*STAR with the Singapore Economic Development Board’s (EDB) support. The post GSK, Sanofi, Takeda and scientists in Singapore partner for biologics appeared first on Pharmaceutical Technology.

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Scienmag

APRIL 27, 2021

Seeing the unseen: HKU scientists develop a new chemical tool that sheds light on how proteins recognise and interact with each other Credit: The University of Hong Kong A research group led by Professor Xiang David LI from the Research Division for Chemistry and the Department of Chemistry, The University of Hong Kong, has developed […].

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Scienmag

JUNE 16, 2022

Scientists are starting to understand the precise workings of a type of gene that, unlike other genes, does not code for proteins – the building blocks of life.

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Scienmag

JULY 6, 2022

LA JOLLA—(July 6, 2022) Understanding how HIV replicates within cells is key for developing new therapies that could help nearly 40 million people living with HIV globally.

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Medical Xpress

APRIL 19, 2023

In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of premature cells called liver progenitor cells.

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STAT News

OCTOBER 13, 2022

Every two years since 1994, scientists have come together for an experiment — better described as a competition — where teams of computational biologists try to predict what proteins will look like in 3D given their amino acid sequence. In 2020, its successor, AlphaFold2, achieved near-perfect scores.

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Scienmag

JULY 6, 2021

Credit: Lorna Dougan/Phospho Animations Scientists at the University of Leeds have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins. But one […].

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Pharmaceutical Technology

JANUARY 4, 2023

Findings from a study, which was conducted by Transcenta and Shanghai Jiao Tong University scientists on TST003 to treat androgen receptor-negative/low prostate cancer, were published by Nature Cancer in May last year. The Gremlin1 protein was found to promote lineage plasticity while driving castration resistance in prostate cancer.

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Pharmaceutical Technology

AUGUST 17, 2022

VLA15 is the only vaccine for Lyme disease in clinical development, according to GlobalData, the parent company of Pharmaceutical Technology. Sanofi had previously developed its own vaccine ImuLyme , which even completed Phase III evaluation, but it did not enter the market. A one-size-fits-all approach.

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Pharma Mirror

APRIL 21, 2024

With the rapid development of biotechnology and molecular medicine, the introduction of mRNA as a vaccine or therapeutic agent enables the production of almost any desired functional protein/peptide within the human body.

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Pharmaceutical Technology

NOVEMBER 29, 2022

Researchers at City of Hope in the US have developed a new potential therapy to treat glioblastoma multiforme (GBM), a kind of brain cancer. For this approach, the team leveraged an oncolytic herpes simplex virus for releasing chemokines, which are signalling proteins that aid in attracting immune cells to tumours.

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Pharmaceutical Technology

APRIL 20, 2023

Targovax has unveiled plans to rebrand as Circio , reflecting its strategic shift to focus on expediting the development of its innovative circular RNA (circRNA) platform. In addition to new regulatory functionalities, this feature may result in stronger and more durable protein expression.

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Scienmag

AUGUST 31, 2020

A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors. The researchers […].

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Medical Xpress

MARCH 1, 2023

Scientists at VCU Massey Cancer Center have uncovered a previously unrecognized relationship between two sets of proteins that operate in tandem to fend off the growth of pancreatic cancer. The findings could provide pivotal information for the development of novel therapies for what is currently an incurable disease.

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Protein Scientist Development Research 73

XTalks

JANUARY 12, 2022

A team of scientists from Harvard T.H. The innovative food packaging is made from a type of corn protein called zein , starch and other naturally-derived biopolymers, which have been found to be sustainable replacements for PFAS and other plastic-coated paper. So, how does it work? million tons of waste in 2018.

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Scienmag

JANUARY 11, 2022

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Scientists at St. Jude Children’s Research Hospital studied the Vsx2 super-enhancer and its role in the development of the retina. Their assessment showed the super-enhancer has four […].

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Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

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Pharmaceutical Technology

DECEMBER 5, 2022

The hub will connect Queensland scientists with the teams at Sanofi’s mRNA Centre of Excellence in the US and France, putting them at the front of international vaccine development and biomedical research. In October, Sanofi and BioMed X signed a research partnership to utilise artificial intelligence (AI) for developing drugs.

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Scienmag

MAY 17, 2022

These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in the production of therapeutic proteins like insulin, plasmids are broadly used in the large-scale production of many bioproducts. Plasmids have extensive use in basic and applied biology.

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Medical Xpress

FEBRUARY 16, 2023

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers. In mice with colon cancer, the drug prevented or dramatically slowed formation of tumors.

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BioPharma Reporter

MAY 3, 2023

Protein drugs are notoriously difficult to deliver orally â but scientists have developed a new type of oral capsule that could deliver insulin and other similar drugs.

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Scienmag

MAY 4, 2022

Scientists at Emory have revealed widespread distortions of a cell’s protein interaction machinery resulting from cancer-causing mutations. They developed a process resembling ground-penetrating radar, for its ability to map the hidden landscape of anticancer drug opportunities. The results are published in Cell.

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Scienmag

DECEMBER 24, 2020

Credit: Tohoku University Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. The findings were detailed […].

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Scienmag

NOVEMBER 17, 2020

Scientists have established a new method to image proteins that could lead to new discoveries in disease through biological tissue and cell analysis and the development of new biomaterials that can be used for the next generation of drug delivery systems and medical devices.

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pharmaphorum

NOVEMBER 12, 2021

Researchers in the US have developed an artificial intelligence-based tool that is able to predict COVID-19 symptoms and suggest which FDA-approved drugs might be used to treat patients. The tool meanwhile could also be applied to new outbreaks of other novel viral infections as they emerge, according to the scientists.

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Medical Xpress

MAY 4, 2023

Scientists from Singapore have demonstrated the critical role played by a special transporter protein in regulating the brain cells that ensure nerves are protected by coverings called myelin sheaths.

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BioPharma Reporter

OCTOBER 22, 2020

Scientists have used gene therapy and a newly developed light-sensing protein to restore sight in mice: with the technology to start clinical trials in the US later this year.

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Scienmag

FEBRUARY 9, 2022

Some of our basic understanding about learning and memory comes from the study of conditions in which cognitive development is disrupted. For example, FMRP, a protein whose loss causes fragile X syndrome, intellectual disability, and some forms of autism has been shown […].

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pharmaphorum

DECEMBER 24, 2020

A serotonin sensor designed using Artificial Intelligence (AI) could help scientists study sleep and mental health and potentially find new neurology drugs. The US National Institutes of Health said that the research it had co-funded used AI to transform a bacterial protein into a new research tool.

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Pharmaceutical Technology

JANUARY 25, 2023

Development of PROTACs (PROteolysis TArgeting Chimeras) has advanced fairly rapidly as excitement grows over their potential to selectively degrade proteins that are involved in various diseases, including cancer. PROTACs are a type of heterobifunctional degrader that offers multiple advantages over traditional small molecules.

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BioPharma Reporter

SEPTEMBER 28, 2023

Scientists from the Universities of Bath and Bristol have identified a molecule that can prevent tangling of a brain protein that is linked to diseases such as Parkinsonâs.

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Protein Scientist Development 111

World of DTC Marketing

APRIL 11, 2021

QUICK THOUGHT: People believe the COVID-19 vaccine was developed in less than a year but that’s not true. Based on the virus a number of vaccines targeting the spike protein were designed, tested in animal models and found to be quite promising against SARS and other coronavirus illnesses like Middle East respiratory syndrome.

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Scienmag

JUNE 25, 2021

research published in Neuron shows how the loss of the protein hepaCAM drives brain development dysfunction and plays an important role in neurological disorders Credit: Baldwin Lab, UNC School of Medicine CHAPEL HILL, NC – When we think of the brain, we think of neurons. Led by Katie Baldwin, Ph.D.,

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Scienmag

JULY 19, 2021

Scientists collaborate to model the complex protein responsible for SARS-CoV-2 replication, revealing its potential weak spots for drug development Credit: Greg Hura/Berkeley Lab In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C.,

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